| dbo:abstract |
le MEF2 (pour « myocyte enhancer factor-2 ») est une protéine jouant un rôle de facteur de transcription. (fr) In the field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are important regulators of cellular differentiation and consequently play a critical role in embryonic development. In adult organisms, Mef2 proteins mediate the stress response in some tissues. Mef2 proteins contain both MADS-box and Mef2 DNA-binding domains. (en) Mef2（myocyte enhancer factor 2）は、遺伝子発現の制御を通じて細胞分化の調節因子として機能し、胚発生に重要な役割を果たす転写因子ファミリーである。成体では、Mef2タンパク質は一部の組織でストレス応答を媒介する。Mef2タンパク質には、MADSボックスとMef2 DNA結合ドメインが存在する。 (ja) |
| dbo:thumbnail |
wiki-commons:Special:FilePath/1N6J.png?width=300 |
| dbo:wikiPageExternalLink |
https://www.orthodb.org/%3Flevel=&species=&query=729387at2759 |
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| dbo:wikiPageWikiLink |
dbr:Enhancer_(genetics) dbr:Neural_crest dbr:MEF2B dbr:MEF2C dbr:MEF2D dbr:C-terminal dbr:Basic_helix-loop-helix dbr:DLX5 dbr:DNA-binding_domain dbr:Vertebrate dbr:Developmental_biology dbr:Creatine_kinase dbr:Gene_expression dbr:Gene dbr:Stress_(biological) dbr:DLX6 dbr:Eukaryote dbr:Cellular_differentiation dbr:Transcription_factor dbr:Protein dbr:Craniofacial dbc:Transcription_factors dbc:Drosophila_melanogaster_genes dbr:Yeast dbr:MADS-box dbr:Serum_response_factor dbr:Nuclear_localization_signal dbr:Myocyte-specific_enhancer_factor_2A dbr:Molecular_biology dbr:Ventricular_hypertrophy dbr:Promoter_(biology) dbr:N-terminal dbr:Homeodomain dbr:File:1N6J.png dbr:File:MEF2_schematic.png |
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dbt:Clear dbt:MeshName dbt:Reflist dbt:Short_description dbt:PDB dbt:Transcription_factors |
| dcterms:subject |
dbc:Transcription_factors dbc:Drosophila_melanogaster_genes |
| gold:hypernym |
dbr:Family |
| rdf:type |
yago:WikicatTranscriptionFactors yago:Abstraction100002137 yago:Arrangement107938773 yago:Beginning107290905 yago:Cause107326557 yago:Event100029378 yago:Factor107327805 yago:Gene105436752 yago:Group100031264 yago:Happening107283608 yago:Ordering108456993 yago:Origin107323922 yago:PsychologicalFeature100023100 yago:YagoPermanentlyLocatedEntity yago:Sequence108459252 yago:Series108457976 yago:WikicatEukaryoteGenes |
| rdfs:comment |
le MEF2 (pour « myocyte enhancer factor-2 ») est une protéine jouant un rôle de facteur de transcription. (fr) In the field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are important regulators of cellular differentiation and consequently play a critical role in embryonic development. In adult organisms, Mef2 proteins mediate the stress response in some tissues. Mef2 proteins contain both MADS-box and Mef2 DNA-binding domains. (en) Mef2（myocyte enhancer factor 2）は、遺伝子発現の制御を通じて細胞分化の調節因子として機能し、胚発生に重要な役割を果たす転写因子ファミリーである。成体では、Mef2タンパク質は一部の組織でストレス応答を媒介する。Mef2タンパク質には、MADSボックスとMef2 DNA結合ドメインが存在する。 (ja) |
| rdfs:label |
MEF2 (fr) Mef2 (en) Mef2 (ja) |
| owl:sameAs |
freebase:Mef2 yago-res:Mef2 wikidata:Mef2 dbpedia-fr:Mef2 dbpedia-ja:Mef2 https://global.dbpedia.org/id/6XrP4 |
| prov:wasDerivedFrom |
wikipedia-en:Mef2?oldid=1099505802&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/1N6J.png wiki-commons:Special:FilePath/MEF2_schematic.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Mef2 |
| is dbo:wikiPageRedirects of |
dbr:Myocyte_Enhancer_Factor dbr:MEF2 dbr:Mef2_transcription_factor |
| is dbo:wikiPageWikiLink of |
dbr:MEF2B dbr:MEF2C dbr:MEF2D dbr:C3orf58 dbr:Histone_acetylation_and_deacetylation dbr:Transcription_factor dbr:AMP-activated_protein_kinase dbr:Michael_E._Greenberg dbr:MADS-box dbr:Myocyte_Enhancer_Factor dbr:MyoD dbr:Myocyte-specific_enhancer_factor_2A dbr:Myogenesis dbr:Myostatin dbr:MEF2 dbr:Mef2_transcription_factor |
| is foaf:primaryTopic of |
wikipedia-en:Mef2 |
