Methylarsonate reductase (original) (raw)
In enzymology, a methylarsonate reductase (EC 1.20.4.2) is an enzyme that catalyzes the chemical reaction methylarsonate + 2 glutathione methylarsonite + glutathione disulfide + H2O Thus, the two substrates of this enzyme are and glutathione, whereas its 3 products are , glutathione disulfide, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with disulfide as acceptor. The systematic name of this enzyme class is gluthathione:methylarsonate oxidoreductase. This enzyme is also called MMA(V) reductase.
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| dbo:abstract | In enzymology, a methylarsonate reductase (EC 1.20.4.2) is an enzyme that catalyzes the chemical reaction methylarsonate + 2 glutathione methylarsonite + glutathione disulfide + H2O Thus, the two substrates of this enzyme are and glutathione, whereas its 3 products are , glutathione disulfide, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with disulfide as acceptor. The systematic name of this enzyme class is gluthathione:methylarsonate oxidoreductase. This enzyme is also called MMA(V) reductase. (en) La méthylarsonate réductase est une oxydoréductase qui catalyse la réaction : + 2 glutathion réduit + disulfure de glutathion + H2O. Cette enzyme intervient dans la détoxication de l'arséniate AsO43– en acide cacodylique (CH3)2AsO2H. (fr) メチルアルソン酸レダクターゼ（methylarsonate reductase）は、次の化学反応を触媒する酸化還元酵素である。 メチルアルソン酸 + 2 グルタチオン メチル亜アルソン酸 + グルタチオンジスルフィド + H2O この酵素の基質はメチルアルソン酸とグルタチオンで、生成物は、グルタチオンジスルフィドとH2Oである。 この酵素は酸化還元酵素に属し、ジスルフィドを受容体としてリンまたはヒ素に特異的に作用する。組織名はgluthathione:methylarsonate oxidoreductaseで、別名にMMA(V) reductaseがある。 (ja) La metilarsonato reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: metil + 2 glutatione ⇄ metil + glutatione disolfuro + H2O Il prodotto, Me-As(OH)2 (acido metilarsonoso), è metilato biologicamente dalla arsenito metiltransferasi (numero EC 2.1.1.137), per formare acido cacodilico (acido dimetilarsinico). (it) |
| dbo:ecNumber | 1.20.4.2 |
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| dbo:wikiPageLength | 1543 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 917519239 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:List_of_enzymes dbr:Enzymology dbc:Enzymes_of_unknown_structure dbr:Chemical_reaction dbr:Enzyme dbr:Glutathione dbr:Glutathione_disulfide dbr:Substrate_(biochemistry) dbr:Product_(chemistry) dbc:EC_1.20.4 dbr:Catalysis dbr:Water dbr:Oxidoreductase dbr:Methylarsonate dbr:Methylarsonite |
| dbp:ecNumber | 1.200000 (xsd:double) |
| dbp:goCode | 50610 (xsd:integer) |
| dbp:iubmbEcNumber | 1 (xsd:integer) |
| dbp:name | methylarsonate reductase (en) |
| dbp:wikiPageUsesTemplate | dbt:Cite_journal dbt:EC_number dbt:Enzyme dbt:Enzymes dbt:Other_oxidoreductases dbt:Portal_bar dbt:Reflist dbt:1.20-enzyme-stub |
| dct:subject | dbc:Enzymes_of_unknown_structure dbc:EC_1.20.4 |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymesOfUnknownStructure |
| rdfs:comment | In enzymology, a methylarsonate reductase (EC 1.20.4.2) is an enzyme that catalyzes the chemical reaction methylarsonate + 2 glutathione methylarsonite + glutathione disulfide + H2O Thus, the two substrates of this enzyme are and glutathione, whereas its 3 products are , glutathione disulfide, and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with disulfide as acceptor. The systematic name of this enzyme class is gluthathione:methylarsonate oxidoreductase. This enzyme is also called MMA(V) reductase. (en) La méthylarsonate réductase est une oxydoréductase qui catalyse la réaction : + 2 glutathion réduit + disulfure de glutathion + H2O. Cette enzyme intervient dans la détoxication de l'arséniate AsO43– en acide cacodylique (CH3)2AsO2H. (fr) メチルアルソン酸レダクターゼ（methylarsonate reductase）は、次の化学反応を触媒する酸化還元酵素である。 メチルアルソン酸 + 2 グルタチオン メチル亜アルソン酸 + グルタチオンジスルフィド + H2O この酵素の基質はメチルアルソン酸とグルタチオンで、生成物は、グルタチオンジスルフィドとH2Oである。 この酵素は酸化還元酵素に属し、ジスルフィドを受容体としてリンまたはヒ素に特異的に作用する。組織名はgluthathione:methylarsonate oxidoreductaseで、別名にMMA(V) reductaseがある。 (ja) La metilarsonato reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: metil + 2 glutatione ⇄ metil + glutatione disolfuro + H2O Il prodotto, Me-As(OH)2 (acido metilarsonoso), è metilato biologicamente dalla arsenito metiltransferasi (numero EC 2.1.1.137), per formare acido cacodilico (acido dimetilarsinico). (it) |
| rdfs:label | Méthylarsonate réductase (fr) Metilarsonato reduttasi (it) メチルアルソン酸レダクターゼ (ja) Methylarsonate reductase (en) |
| owl:sameAs | freebase:Methylarsonate reductase yago-res:Methylarsonate reductase wikidata:Methylarsonate reductase dbpedia-fr:Methylarsonate reductase dbpedia-it:Methylarsonate reductase dbpedia-ja:Methylarsonate reductase dbpedia-sh:Methylarsonate reductase dbpedia-sr:Methylarsonate reductase https://global.dbpedia.org/id/3ZbXo |
| prov:wasDerivedFrom | wikipedia-en:Methylarsonate_reductase?oldid=917519239&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Methylarsonate_reductase |
| foaf:name | methylarsonate reductase (en) |
| is dbo:wikiPageRedirects of | dbr:Gluthathione:methylarsonate_oxidoreductase dbr:EC_1.20.4.2 |
| is dbo:wikiPageWikiLink of | dbr:List_of_EC_numbers_(EC_1) dbr:Gluthathione:methylarsonate_oxidoreductase dbr:EC_1.20.4.2 |
| is foaf:primaryTopic of | wikipedia-en:Methylarsonate_reductase |