| dbo:abstract |
The laboratory mouse has been instrumental in investigating the genetics of human disease, including cancer, for over 110 years. The laboratory mouse has physiology and genetic characteristics very similar to humans providing powerful models for investigation of the genetic characteristics of disease. The Mouse Models of Human Cancer database (MMHCdb) is a unique, comprehensive online knowledgebase of mouse models of human cancer hosted by The Jackson Laboratory with funding from the National Cancer Institute (NCI). MMHCdb is part of the Mouse Genome Informatics consortium (MGI) and was first released in 1998 as the Mouse Tumor Biology (MTB) database. MMHCdb contains genetic and genomic information about inbred mouse strains, genetically engineered mouse models (GEMMs) and Patient Derived Xenograft (PDX) models of human cancer. Data in MMHCdb is expertly curated from peer-reviewed scientific publications or obtained as direct data submissions from individual investigators and large-scale research initiatives. MMHCdb, in collaboration with EMBL-EBI, co-developed the PDX Finder resource which serves as a global catalog of PDX models. (en) |
| dbo:thumbnail |
wiki-commons:Special:FilePath/MMHCdb_Logo.jpg?width=300 |
| dbo:title |
Mouse Models of Human Cancer database (en) |
| dbo:wikiPageExternalLink |
http://www.informatics.jax.org/ http://tumor.informatics.jax.org/mtbwi/index.do https://www.jax.org/ http://bhmtbdb01.jax.org/mtbwi/pdxLikeMe.do http://www.pdxfinder.org/ http://www.tumor.informatics.jax.org/ https://www.youtube.com/watch%3Fv=yxkaabIH7Ns https://www.jax.org/jax-mice-and-services/customer-support/technical-support/genetics-and-nomenclature http://tumor.informatics.jax.org/mtbwi/dynamicGrid.do http://tumor.informatics.jax.org/mtbwi/facetedSearch.do%3Fstart=0&fq=organParent%3ALung&fq=tcParent%3Aadenocarcinoma&fq=pathologyImages:%5b*%20TO%20*%5d |
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dbr:Cancer dbr:NSG_mouse dbr:Patient_derived_xenograft dbr:Animal_models dbr:C57BL/6J dbr:Mouse_model dbc:Cancer_research dbr:Inbred_strain dbr:Genome_editing dbr:Mutations dbr:HRAS dbr:American_Association_for_Cancer_Research dbc:Genetics_databases dbr:Carcinoma dbr:Genetically_engineered_mouse_model dbr:Jackson_Laboratory dbr:Laboratory_mouse dbc:Laboratory_mice dbr:Immunodeficient dbr:Phenotypes dbr:National_Cancer_Institute dbr:Genomic dbr:Mouse_Genome_Informatics dbr:Molecular_biology dbr:Transgene dbr:Transgenics dbr:EMBL-EBI dbr:Humanized dbr:Inbred_strains dbr:The_Jackson_Laboratory dbr:File:Faceted_Search_example.jpg dbr:File:PDX_Like_Me.jpg dbr:File:TumorGridWiki.jpg dbr:Mus_musculus,_Homo_sapiens |
| dbp:center |
dbr:The_Jackson_Laboratory |
| dbp:citation |
Krupke et al. PMID: 29092943 (en) |
| dbp:description |
Resource for information on mouse models of human cancer. (en) |
| dbp:logo |
MMHCdb Logo.jpg (en) |
| dbp:organism |
Mus musculus, Homo sapiens (en) |
| dbp:scope |
Mouse models, genetics, genomics, tumor pathology images. (en) |
| dbp:title |
Mouse Models of Human Cancer database (en) |
| dbp:url |
http://www.tumor.informatics.jax.org/ |
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dbt:Infobox_biodatabase dbt:Reflist |
| dc:description |
Resource for information on mouse models of human cancer. |
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dbc:Cancer_research dbc:Genetics_databases dbc:Laboratory_mice |
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owl:Thing schema:CreativeWork dbo:Work wikidata:Q386724 dbo:Database dul:InformationObject dbo:BiologicalDatabase |
| rdfs:comment |
The laboratory mouse has been instrumental in investigating the genetics of human disease, including cancer, for over 110 years. The laboratory mouse has physiology and genetic characteristics very similar to humans providing powerful models for investigation of the genetic characteristics of disease. (en) |
| rdfs:label |
Mouse Models of Human Cancer database (en) |
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wikidata:Mouse Models of Human Cancer database https://global.dbpedia.org/id/C8J7Y |
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wikipedia-en:Mouse_Models_of_Human_Cancer_database?oldid=1122535371&ns=0 |
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wiki-commons:Special:FilePath/Faceted_Search_example.jpg wiki-commons:Special:FilePath/MMHCdb_Logo.jpg wiki-commons:Special:FilePath/PDX_Like_Me.jpg wiki-commons:Special:FilePath/TumorGridWiki.jpg |
| foaf:homepage |
http://www.tumor.informatics.jax.org/ |
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wikipedia-en:Mouse_Models_of_Human_Cancer_database |
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wikipedia-en:Mouse_Models_of_Human_Cancer_database |
