| dbo:abstract |
Mucoadhesion describes the attractive forces between a biological material and mucus or mucous membrane. Mucous membranes adhere to epithelial surfaces such as the gastrointestinal tract (GI-tract), the vagina, the lung, the eye, etc. They are generally hydrophilic as they contain many hydrogen macromolecules due to the large amount of water (approximately 95%) within its composition. However, mucin also contains glycoproteins that enable the formation of a gel-like substance. Understanding the hydrophilic bonding and adhesion mechanisms of mucus to biological material is of utmost importance in order to produce the most efficient applications. For example, in drug delivery systems, the mucus layer must be penetrated in order to effectively transport micro- or nanosized drug particles into the body. Bioadhesion is the mechanism by which two biological materials are held together by interfacial forces. (en) Мукоадгезия — это способность некоторых материалов к прилипанию (адгезии) к поверхности слизистых тканей в теле человека или животных. Мукоадгезия является частным случаем биоадгезии, которая рассматривает прилипание материалов к любым биологическим поверхностям. (ru) |
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| dbo:wikiPageWikiLink |
dbc:Body_fluids dbr:Electrical_mobility dbr:Mucous_membrane dbr:Mucus dbr:Blood-brain_barrier dbr:Hydrogen_bond dbr:Hydrophilic dbr:DLVO_theory dbr:Van_der_Waals_force dbr:Electrostatic dbr:Route_of_administration dbc:Adhesives dbc:Biomolecules dbr:Corneal_epithelium dbr:Chemical_bond dbr:Nasal_cavity dbr:Electrical_double_layer dbr:Entropy dbr:Gel dbr:Glycoproteins dbr:Blink dbr:Andreas_Bernkop-Schnürch dbr:Wilhelmy_plate dbr:Drug_delivery dbr:Du_Noüy_ring_method dbr:Steric_effects dbr:Cilium dbr:Bioadhesion dbr:Bioadhesives dbr:Diffusion dbr:Fracture dbr:Diffusion_coefficient dbr:Mass_diffusivity dbr:Molecular_diffusion dbr:Tears dbr:Hydrophobe dbr:Adsorption dbr:Bioavailability dbr:Tablet_(pharmacy) dbr:Coagulation dbr:Wetting dbc:Excretion dbc:Routes_of_administration dbr:Human_eye dbr:Hydrogen_bonds dbr:Buccal_administration dbr:Saliva dbr:Ultimate_tensile_strength dbr:Thin-film_drug_delivery dbr:Solubility dbr:Structural_integrity_and_failure dbr:Strength_of_materials dbr:Thiomer dbr:Sublingual_administration dbr:Residence_time_(fluid_dynamics) dbr:Van_der_Waals_forces dbr:Van_der_waals_force dbr:Thiomers dbr:File:Contraceptivepatch.jpg dbr:File:Mucoadhesion_Fracture_Theory_(fixed).png dbr:File:Mucoadhesion_Interpenetration.png dbr:File:Mucoadhesion_before_and_after_hydrating_mucus.png dbr:File:FlattenedRoundPills.jpg |
| dbp:wikiPageUsesTemplate |
dbt:Reflist |
| dcterms:subject |
dbc:Body_fluids dbc:Adhesives dbc:Biomolecules dbc:Excretion dbc:Routes_of_administration |
| gold:hypernym |
dbr:Mechanism |
| rdf:type |
dbo:Organisation |
| rdfs:comment |
Мукоадгезия — это способность некоторых материалов к прилипанию (адгезии) к поверхности слизистых тканей в теле человека или животных. Мукоадгезия является частным случаем биоадгезии, которая рассматривает прилипание материалов к любым биологическим поверхностям. (ru) Mucoadhesion describes the attractive forces between a biological material and mucus or mucous membrane. Mucous membranes adhere to epithelial surfaces such as the gastrointestinal tract (GI-tract), the vagina, the lung, the eye, etc. They are generally hydrophilic as they contain many hydrogen macromolecules due to the large amount of water (approximately 95%) within its composition. However, mucin also contains glycoproteins that enable the formation of a gel-like substance. Understanding the hydrophilic bonding and adhesion mechanisms of mucus to biological material is of utmost importance in order to produce the most efficient applications. For example, in drug delivery systems, the mucus layer must be penetrated in order to effectively transport micro- or nanosized drug particles into (en) |
| rdfs:label |
Mucoadhesion (en) Мукоадгезия (ru) |
| owl:sameAs |
freebase:Mucoadhesion yago-res:Mucoadhesion wikidata:Mucoadhesion dbpedia-ru:Mucoadhesion https://global.dbpedia.org/id/2PGhs |
| prov:wasDerivedFrom |
wikipedia-en:Mucoadhesion?oldid=1049632838&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Contraceptivepatch.jpg wiki-commons:Special:FilePath/Mucoadhesion_Fracture_Theory_(fixed).png wiki-commons:Special:FilePath/Mucoadhesion_Interpenetration.png wiki-commons:Special:FilePath/Mucoadhesion_before_and_after_hydrating_mucus.png wiki-commons:Special:FilePath/FlattenedRoundPills.jpg |
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wikipedia-en:Mucoadhesion |
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dbr:Mucus dbr:Maleimide dbr:Adhesion dbr:Bioadhesive dbr:Polyaspartic_acid dbr:Thiomer |
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wikipedia-en:Mucoadhesion |
