ENU (original) (raw)
- N-Ethyl-N-nitrosoharnstoff, oft auch als Ethylnitrosoharnstoff bezeichnet und meist als ENU (= ethyl nitroso urea) abgekürzt, ist eine Verbindung aus der Gruppe der Nitrosoharnstoffe. Es ist ein starkes Karzinogen und hochpotentes Mutagen. (de)
- ENU, also known as N-ethyl-N-nitrosourea (chemical formula C3H7N3O2), is a highly potent mutagen. For a given gene in mice, ENU can induce 1 new mutation in every 700 loci. It is also toxic at high doses. The chemical is an alkylating agent, and acts by transferring the ethyl group of ENU to nucleobases (usually thymine) in nucleic acids. Its main targets are the spermatogonial stem cells, from which mature sperm are derived. (en)
- L'ENU ou N-ethyl-N-nitrosourea pour les anglophones ou N-nitroso-N-éthylurée pour les francophones est un agent mutagène utilisé particulièrement pour la mutagenèse des gamètes. (fr)
- N-etil-N-nitrosourea adalah salah satu jenis yang memiliki aktivitas yang sangat tinggi. N-etil-N-nitrosourea dapat berbentuk kristal maupun bubuk. Kristalnya berwarna kuning-merah muda, sedangkan bubuknya berwarna putih. N-etil-N-nitrosourea dimanfaatkan sebagai mutagen dan karsinogen dalam percobaan ilmiah. N-etil-N-nitrosourea bekerja dengan cara menginduksi , sehingga asam deksiribonukleat menjadi rusak. Formula molekulnya adalah C3H7N3O2. N-etil-N-nitrosourea bersifat beracun akut, dapat menyebabkan iritasi, dan dapat membahayakan kesehatan lingkungan di sekitarnya. (in)
- N-ethyl-N-nitroso-ureum of ENU is een sterk mutagene organische verbinding met als brutoformule C3H7N3O2. De zuivere stof komt voor als een geelroze kristallijne vaste stof, die goed oplosbaar is in water. Bij muizen veroorzaakt ze 1 mutatie per gen en per 700 gameten. N-ethyl-N-nitroso-ureum is een alkylerende verbinding die een ethylgroep overdraagt op nucleobasen (voornamelijk thymine) in nucleïnezuren. (nl)
- N-Ethylnitrosourea (en)
- N-Nitroso-N-Ethylurea (en)
- Nitrosoethylurea (en)
- 1-Ethyl-1-nitrosourea (en)
- N-Ethyl-N-nitrosourea (en)
- http://mutagenetix.scripps.edu/default.cfm%3Fpage=start
- http://www.gsc.riken.go.jp/Mouse/main.htm
- http://www.har.mrc.ac.uk/services/mutagenesis/
- http://www.helmholtz-muenchen.de/en/ieg/group-genome-project/enu-screen/index.html
- http://www.apf.edu.au/
- http://cshprotocols.cshlp.org/cgi/content/full/2008/5/pdb.prot4985
- https://web.archive.org/web/20080512023235/http:/www.mouse-genome.bcm.tmc.edu/ENU/MutagenesisProj.asp
- https://web.archive.org/web/20080608131713/http:/mouse.ornl.gov/mmdb/index.html
- https://web.archive.org/web/20080612041255/http:/pga.jax.org/protocol_008.html
- https://web.archive.org/web/20080618041904/http:/reproductivegenomics.jax.org/index.html
- https://web.archive.org/web/20080620080908/http:/nmf.jax.org/index.html
- http://www.northwestern.edu/neurobiology/faculty/pinto2.html
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- N-Ethyl-N-nitrosoharnstoff, oft auch als Ethylnitrosoharnstoff bezeichnet und meist als ENU (= ethyl nitroso urea) abgekürzt, ist eine Verbindung aus der Gruppe der Nitrosoharnstoffe. Es ist ein starkes Karzinogen und hochpotentes Mutagen. (de)
- ENU, also known as N-ethyl-N-nitrosourea (chemical formula C3H7N3O2), is a highly potent mutagen. For a given gene in mice, ENU can induce 1 new mutation in every 700 loci. It is also toxic at high doses. The chemical is an alkylating agent, and acts by transferring the ethyl group of ENU to nucleobases (usually thymine) in nucleic acids. Its main targets are the spermatogonial stem cells, from which mature sperm are derived. (en)
- L'ENU ou N-ethyl-N-nitrosourea pour les anglophones ou N-nitroso-N-éthylurée pour les francophones est un agent mutagène utilisé particulièrement pour la mutagenèse des gamètes. (fr)
- N-etil-N-nitrosourea adalah salah satu jenis yang memiliki aktivitas yang sangat tinggi. N-etil-N-nitrosourea dapat berbentuk kristal maupun bubuk. Kristalnya berwarna kuning-merah muda, sedangkan bubuknya berwarna putih. N-etil-N-nitrosourea dimanfaatkan sebagai mutagen dan karsinogen dalam percobaan ilmiah. N-etil-N-nitrosourea bekerja dengan cara menginduksi , sehingga asam deksiribonukleat menjadi rusak. Formula molekulnya adalah C3H7N3O2. N-etil-N-nitrosourea bersifat beracun akut, dapat menyebabkan iritasi, dan dapat membahayakan kesehatan lingkungan di sekitarnya. (in)
- N-ethyl-N-nitroso-ureum of ENU is een sterk mutagene organische verbinding met als brutoformule C3H7N3O2. De zuivere stof komt voor als een geelroze kristallijne vaste stof, die goed oplosbaar is in water. Bij muizen veroorzaakt ze 1 mutatie per gen en per 700 gameten. N-ethyl-N-nitroso-ureum is een alkylerende verbinding die een ethylgroep overdraagt op nucleobasen (voornamelijk thymine) in nucleïnezuren. (nl)
- ENU (en)
- N-Ethyl-N-nitrosoharnstoff (de)
- N-etil-N-nitrosourea (in)
- ENU (fr)
- N-ethyl-N-nitroso-ureum (nl)
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