NBD-TMA (original) (raw)
NBD-TMA ([2-(4-nitro-2,1,3-benzoxadiazol-7-yl)aminoethyl]trimethylammonium) is a small, positively charged (+1) fluorescent dye. It was also known as EAM-1 (N,N,N,-Trimethyl-2[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanaminium iodide) when it was briefly supplied by as an iodide complex. NBD-TMA was designed as a probe for monitoring renal transport of organic cations. As a small, positively charged fluorophore, it has also seen use as a tracer for measuring gap junction coupling in cases of cation selective connexin channels.
| Property | Value |
|---|---|
| dbo:abstract | NBD-TMA ([2-(4-nitro-2,1,3-benzoxadiazol-7-yl)aminoethyl]trimethylammonium) is a small, positively charged (+1) fluorescent dye. It was also known as EAM-1 (N,N,N,-Trimethyl-2[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanaminium iodide) when it was briefly supplied by as an iodide complex. NBD-TMA has an excitation maximum at 458 nm and an emission maximum at 530 nm. It also has a smaller local excitation maximum around 343 nm. The molar extinction coefficient is about 13,000 cm−1M−1 and its overall effective fluorescence is about 1% that of fluorescein. It is only mildly sensitive to halide ion collision quenching. NBD-TMA was designed as a probe for monitoring renal transport of organic cations. As a small, positively charged fluorophore, it has also seen use as a tracer for measuring gap junction coupling in cases of cation selective connexin channels. (en) |
| dbo:iupacName | N,N,N-Trimethyl-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethan-1-aminium (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/NBD-TMA.svg?width=300 |
| dbo:wikiPageID | 2600552 (xsd:integer) |
| dbo:wikiPageLength | 2209 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1093988571 (xsd:integer) |
| dbo:wikiPageWikiLink | dbc:Ethyleneamines dbc:Fluorescent_dyes dbc:Nitro_compounds dbc:Secondary_amines dbr:Connexin dbr:Gap_junction dbr:Ion dbr:Amine dbc:Quaternary_ammonium_compounds dbr:Fluorescein dbr:Fluorophore dbr:Molar_extinction_coefficient dbr:Iodide dbr:Kidney dbr:Azole dbc:Benzoxadiazoles dbr:Nanometre dbr:Halide_ion dbr:Macrocyclics_Company |
| dbp:imagefile | NBD-TMA.svg (en) |
| dbp:imagesize | 120 (xsd:integer) |
| dbp:pin | N,N,N-Trimethyl-2-[amino]ethan-1-aminium (en) |
| dbp:wikiPageUsesTemplate | dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:PMID |
| dct:subject | dbc:Ethyleneamines dbc:Fluorescent_dyes dbc:Nitro_compounds dbc:Secondary_amines dbc:Quaternary_ammonium_compounds dbc:Benzoxadiazoles |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:Abstraction100002137 yago:ColoringMaterial114984973 yago:Dye114985383 yago:Material114580897 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:ChemicalCompound yago:Substance100019613 yago:WikicatDyes |
| rdfs:comment | NBD-TMA ([2-(4-nitro-2,1,3-benzoxadiazol-7-yl)aminoethyl]trimethylammonium) is a small, positively charged (+1) fluorescent dye. It was also known as EAM-1 (N,N,N,-Trimethyl-2[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanaminium iodide) when it was briefly supplied by as an iodide complex. NBD-TMA was designed as a probe for monitoring renal transport of organic cations. As a small, positively charged fluorophore, it has also seen use as a tracer for measuring gap junction coupling in cases of cation selective connexin channels. (en) |
| rdfs:label | NBD-TMA (en) |
| owl:sameAs | freebase:NBD-TMA yago-res:NBD-TMA wikidata:NBD-TMA https://global.dbpedia.org/id/4rd99 |
| prov:wasDerivedFrom | wikipedia-en:NBD-TMA?oldid=1093988571&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/NBD-TMA.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:NBD-TMA |
| is dbo:wikiPageRedirects of | dbr:EAM-1 |
| is dbo:wikiPageWikiLink of | dbr:Fluorophore dbr:EAM-1 |
| is foaf:primaryTopic of | wikipedia-en:NBD-TMA |
