| dbo:abstract |
NBUMP is a highly selective 5-HT1A receptor partial agonist (Ki = 0.1 nM; IA = 40%) with an arylpiperazine structure. It is one of the highest affinity ligands for the 5-HT1A receptor known. It displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively. (en) |
| dbo:casNumber |
134390-72-0 |
| dbo:fdaUniiCode |
G184WXO36J |
| dbo:pubchem |
64622 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/NBUMP.png?width=300 |
| dbo:wikiPageID |
26522190 (xsd:integer) |
| dbo:wikiPageLength |
2319 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1105896151 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Partial_agonist dbc:Adamantanes dbc:Phenol_ethers dbc:Phenylpiperazines dbc:Serotonin_receptor_agonists dbc:5-HT1A_agonists dbr:Adatanserin dbr:5-HT1A_receptor dbc:Carboxamides dbr:Alpha-1_adrenergic_receptor dbr:Affinity_(pharmacology) dbr:Binding_selectivity dbr:Aryl dbr:Piperazine dbr:D2_receptor |
| dbp:atcPrefix |
none (en) |
| dbp:c |
26 (xsd:integer) |
| dbp:casNumber |
134390 (xsd:integer) |
| dbp:chemspiderid |
58183 (xsd:integer) |
| dbp:h |
39 (xsd:integer) |
| dbp:iupacName |
N-[4-[4-piperazin-1-yl]butyl]adamantane-1-carboxamide (en) |
| dbp:n |
3 (xsd:integer) |
| dbp:o |
2 (xsd:integer) |
| dbp:pubchem |
64622 (xsd:integer) |
| dbp:smiles |
COc1ccccc1N2CCNCCCCNCC34CC5CCCCC4 (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
PRZPXKIXNNNNCD-UHFFFAOYSA-N (en) |
| dbp:unii |
G184WXO36J (en) |
| dbp:verifiedrevid |
424813377 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Piperazines dbt:Reflist dbt:Serotonergics dbt:Short_description dbt:Cascite dbt:Fdacite |
| dcterms:subject |
dbc:Adamantanes dbc:Phenol_ethers dbc:Phenylpiperazines dbc:Serotonin_receptor_agonists dbc:5-HT1A_agonists dbc:Carboxamides |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:Communication100033020 yago:Element114840755 yago:Formula106816935 yago:Matter100020827 yago:Message106598915 yago:MolecularFormula106817173 yago:Part113809207 yago:PhysicalEntity100001930 yago:Quintessence114847103 yago:Relation100031921 dbo:Drug yago:Statement106722453 yago:Substance100019613 yago:WikicatPhenolEthers umbel-rc:DrugProduct |
| rdfs:comment |
NBUMP is a highly selective 5-HT1A receptor partial agonist (Ki = 0.1 nM; IA = 40%) with an arylpiperazine structure. It is one of the highest affinity ligands for the 5-HT1A receptor known. It displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively. (en) |
| rdfs:label |
NBUMP (en) |
| owl:sameAs |
freebase:NBUMP yago-res:NBUMP wikidata:NBUMP dbpedia-sh:NBUMP dbpedia-sr:NBUMP https://global.dbpedia.org/id/JvNi |
| prov:wasDerivedFrom |
wikipedia-en:NBUMP?oldid=1105896151&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/NBUMP.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:NBUMP |
| is dbo:wikiPageRedirects of |
dbr:C26H39N3O2 |
| is dbo:wikiPageWikiLink of |
dbr:C26H39N3O2 dbr:5-HT1A_receptor |
| is foaf:primaryTopic of |
wikipedia-en:NBUMP |
