| dbo:abstract |
NeuroD, nebo Beta2, je základní transkripční faktor exprimovaný v určitých částech mozku, beta buňkách pankreatu a neuroendokrinních buňkách. Podílí se na diferenciaci nervové soustavy a vývoji slinivky břišní. Heterodimerizuje s produkty genu a řídí transkripci různých genů skrze identifikaci a navázání E boxů do jejich promotorové oblasti. U savců existují dva typy tohoto faktoru: * NeuroD1 * NeuroD2 * NeuroD4 * NeuroD6 (cs) NeuroD, also called Beta2, is a basic helix-loop-helix transcription factor expressed in certain parts of brain, beta pancreatic cells and enteroendocrine cells. It is involved in the differentiation of nervous system and development of pancreas. It heterodimerizes with the products of E2A gene and controls the transcription of a variety of genes by identifying and binding E boxes in their promoter region. In rodents NeuroD is involved in the development of the retina. In mammals there are two types of this factor: * NeuroD1 * NeuroD2 * * (en) |
| dbo:wikiPageID |
15199029 (xsd:integer) |
| dbo:wikiPageLength |
1878 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1080536653 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Retina dbc:Transcription_factors dbr:NeuroD1 dbr:NeuroD2 dbr:NeuroD4 dbr:NeuroD6 |
| dbp:wikiPageUsesTemplate |
dbt:Biochemistry-stub dbt:Reflist dbt:Short_description dbt:Transcription_factors |
| dct:subject |
dbc:Transcription_factors |
| gold:hypernym |
dbr:Factor |
| rdf:type |
yago:WikicatTranscriptionFactors yago:Abstraction100002137 yago:Beginning107290905 yago:Cause107326557 yago:Event100029378 yago:Factor107327805 yago:Happening107283608 yago:Origin107323922 yago:PsychologicalFeature100023100 yago:YagoPermanentlyLocatedEntity dbo:Protein |
| rdfs:comment |
NeuroD, nebo Beta2, je základní transkripční faktor exprimovaný v určitých částech mozku, beta buňkách pankreatu a neuroendokrinních buňkách. Podílí se na diferenciaci nervové soustavy a vývoji slinivky břišní. Heterodimerizuje s produkty genu a řídí transkripci různých genů skrze identifikaci a navázání E boxů do jejich promotorové oblasti. U savců existují dva typy tohoto faktoru: * NeuroD1 * NeuroD2 * NeuroD4 * NeuroD6 (cs) NeuroD, also called Beta2, is a basic helix-loop-helix transcription factor expressed in certain parts of brain, beta pancreatic cells and enteroendocrine cells. It is involved in the differentiation of nervous system and development of pancreas. It heterodimerizes with the products of E2A gene and controls the transcription of a variety of genes by identifying and binding E boxes in their promoter region. In rodents NeuroD is involved in the development of the retina. In mammals there are two types of this factor: * NeuroD1 * NeuroD2 * * (en) |
| rdfs:label |
NeuroD (cs) NeuroD (en) |
| owl:sameAs |
freebase:NeuroD yago-res:NeuroD wikidata:NeuroD dbpedia-cs:NeuroD https://global.dbpedia.org/id/4sNTM |
| prov:wasDerivedFrom |
wikipedia-en:NeuroD?oldid=1080536653&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:NeuroD |
| is dbo:wikiPageRedirects of |
dbr:NEUROD |
| is dbo:wikiPageWikiLink of |
dbr:Eomesodermin dbr:Muse_cell dbr:Neurogenins dbr:Basic_helix–loop–helix dbr:Developmental_biology dbr:Neurogenin-3 dbr:Proneural_genes dbr:Fam158a dbr:Follower_neuron dbr:Histone_acetyltransferase dbr:Insulin dbr:Neuronal_lineage_marker dbr:NEUROD1 dbr:NEUROD |
| is foaf:primaryTopic of |
wikipedia-en:NeuroD |