Ovotransferrin (original) (raw)
Ovotransferrin (conalbumin) is a glycoprotein of egg white albumen. Egg white albumen is composed of multiple proteins, of which ovotransferrin is the most heat reliable. It has a molecular weight of 76,000 daltons and contains about 700 amino acids. Ovotransferrin makes up approximately 13% of egg albumen (in contrast to ovalbumin, which comprises 54%). As a member of the transferrin and metalloproteinase family, ovotransferrin has been found to possess antibacterial and antioxydant and immunomodulatory properties, arising primarily through its iron (Fe3+) binding capacity by locking away a key biochemical component necessary for micro-organismal survival. Bacteria starved of iron are rendered incapable of moving, making ovotransferrin a potent bacteriostatic.
| Property | Value |
|---|---|
| dbo:abstract | L'ovotransferrina és una proteïna que lliga ferro de manera reversible i redueix la biodisponibilitat del ferro per als bacteris. Un altre mecanisme d'acció antibacteriana proposat per a l'ovotransferrina és la permeabilització de les membranes cel·lulars, que ocasiona una permeabilitat selectiva d'ions que comporta la dissipació del potencial elèctric de la cèl·lula. Ha demostrat ser eficaç contra un ampli espectre de bacteris, incloent Pseudomonas spp., E. coli, Streptococcus mutans, , Bacillus cereus i Salmonella enteritidis. D'altra banda, és una font important de ferro per a la nutrició humana. La trobem, principalment, a la clara d'ou. (ca) Ovotransferrin (conalbumin) is a glycoprotein of egg white albumen. Egg white albumen is composed of multiple proteins, of which ovotransferrin is the most heat reliable. It has a molecular weight of 76,000 daltons and contains about 700 amino acids. Ovotransferrin makes up approximately 13% of egg albumen (in contrast to ovalbumin, which comprises 54%). As a member of the transferrin and metalloproteinase family, ovotransferrin has been found to possess antibacterial and antioxydant and immunomodulatory properties, arising primarily through its iron (Fe3+) binding capacity by locking away a key biochemical component necessary for micro-organismal survival. Bacteria starved of iron are rendered incapable of moving, making ovotransferrin a potent bacteriostatic. (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/PDB_1gvc_EBI.jpg?width=300 |
| dbo:wikiPageID | 10775911 (xsd:integer) |
| dbo:wikiPageLength | 8008 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1070505642 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Carbohydrate dbr:Nitrogen dbr:Metalloproteinase dbr:Antimicrobial dbr:Lactoferrin dbr:Embryo dbr:Transferrin dbr:Bacteria dbr:Iron-deficiency_anemia dbr:Amino_acid dbr:Dalton_(unit) dbr:Ovalbumin dbr:Cardiovascular_disease dbr:Glycan dbr:Glycoprotein dbr:Glycosylation dbr:Protein_folding dbr:Protein dbr:Iron dbc:Storage_proteins dbr:Asparagine dbr:Asparagus dbc:Blood_proteins dbr:Binding_site dbr:Sulfhydryl_group dbr:Egg_allergy dbr:Egg_white dbr:Homology_(biology) dbr:Disulfide dbc:Avian_proteins dbr:Amino_acid_residues dbr:Covalent_modification dbr:Acute_phase_reactants dbr:File:Basic_N-glycan.svg dbr:File:L-Asparagin_-_L-Asparagine.svg |
| dbp:caption | PDB 1gvc EBI (en) |
| dbp:name | Ovotransferrin (en) |
| dbp:organism | Gallus gallus (en) |
| dbp:uniprot | P02789 (en) |
| dbp:wikiPageUsesTemplate | dbt:Infobox_nonhuman_protein dbt:MeshName dbt:Reflist dbt:Short_description dbt:Albumins |
| dcterms:subject | dbc:Storage_proteins dbc:Blood_proteins dbc:Avian_proteins |
| gold:hypernym | dbr:Glycoprotein |
| rdf:type | yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Protein yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatProteins |
| rdfs:comment | Ovotransferrin (conalbumin) is a glycoprotein of egg white albumen. Egg white albumen is composed of multiple proteins, of which ovotransferrin is the most heat reliable. It has a molecular weight of 76,000 daltons and contains about 700 amino acids. Ovotransferrin makes up approximately 13% of egg albumen (in contrast to ovalbumin, which comprises 54%). As a member of the transferrin and metalloproteinase family, ovotransferrin has been found to possess antibacterial and antioxydant and immunomodulatory properties, arising primarily through its iron (Fe3+) binding capacity by locking away a key biochemical component necessary for micro-organismal survival. Bacteria starved of iron are rendered incapable of moving, making ovotransferrin a potent bacteriostatic. (en) L'ovotransferrina és una proteïna que lliga ferro de manera reversible i redueix la biodisponibilitat del ferro per als bacteris. Un altre mecanisme d'acció antibacteriana proposat per a l'ovotransferrina és la permeabilització de les membranes cel·lulars, que ocasiona una permeabilitat selectiva d'ions que comporta la dissipació del potencial elèctric de la cèl·lula. La trobem, principalment, a la clara d'ou. (ca) |
| rdfs:label | Ovotransferrina (ca) Ovotransferrin (en) |
| owl:sameAs | freebase:Ovotransferrin yago-res:Ovotransferrin wikidata:Ovotransferrin dbpedia-ca:Ovotransferrin https://global.dbpedia.org/id/4sgJp |
| prov:wasDerivedFrom | wikipedia-en:Ovotransferrin?oldid=1070505642&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Basic_N-glycan.svg wiki-commons:Special:FilePath/PDB_1gvc_EBI.jpg wiki-commons:Special:FilePath/L-Asparagin_-_L-Asparagine.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Ovotransferrin |
| is dbo:wikiPageRedirects of | dbr:Conalbumin |
| is dbo:wikiPageWikiLink of | dbr:Conalbumin dbr:Transferrin dbr:Egg_white dbr:Eggshell_membrane dbr:Ovomucoid |
| is foaf:primaryTopic of | wikipedia-en:Ovotransferrin |
