| dbo:abstract |
Das Proctolin (englisch synonym) bezeichnet eine aus fünf Aminosäuren bestehendes Neuropeptid (H-Arg-Tyr-Leu-Pro-Thr-OH), das bei Insekten für die neuromuskulären Synapsen der im Bereich des Enddarms als Neurotransmitter fungiert. Darüber hinaus ist Proctolin immunologisch auch im Zentralnervensystem von Insekten und sogar von Wirbeltieren als weit verbreitet nachzuweisen. Ihm wird eine generelle Neurotransmitterfunktion zugeschrieben. (de) Proctolin is a neuropeptide present in insects and crustaceans. It was first found in Periplaneta americana, a species of cockroach in 1975. Proctolin was extracted from 125,000 cockroaches and the Edman degradation was carried out on the sample to determine the amino acid sequence, which is Arg-Tyr-Leu-Pro-Thr. Proctolin was the first insect neuropeptide to be sequenced. Starratt and Brown identified it as a visceral muscle neurotransmitter. However, it now appears that there are many more functions of proctolin, and it is present in many more species. (en) |
| dbo:alternativeName |
(L)-Arginyl-(L)-tyrosyl-(L)-leucyl-(L)-prolyl-(L)-threonine; Arg-Tyr-Leu-Pro-Thr (en) |
| dbo:iupacName |
(2S,3R)-2-(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoic acid (en) |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Proctolin.svg?width=300 |
| dbo:wikiPageID |
12931795 (xsd:integer) |
| dbo:wikiPageLength |
5912 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1100860260 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Aminopeptidase dbr:Muscle dbr:DNA dbr:Neuropeptide dbr:Neurotransmitter dbr:Periplaneta_americana dbr:Cotransmitter dbr:Crustacean dbr:Chemical_structure dbr:Neuron dbr:Cockroach dbr:Coleoptera dbr:Enzyme dbr:Gene dbr:Mollusc dbr:Annelid dbr:Aorta dbr:Mammal dbr:Synapse dbr:Active_site dbr:Drosophila_melanogaster dbr:Head dbr:Amino_acid dbr:Diploptera_punctata dbr:Edman_degradation dbr:Hindgut dbr:Precursor_(chemistry) dbr:Receptor_(biochemistry) dbr:Hemiptera dbc:Pentapeptides dbc:Neuropeptides dbr:Homogenization_(biology) dbr:Diptera dbr:Insect dbr:Insecticides dbr:Orthoptera dbr:Neurohormone dbr:Side_chain dbr:Rhodnius_prolixus dbr:Glutamate dbr:Analog_(chemistry) dbr:Gene_sequence dbr:Mimetics dbr:Peptidase dbr:Neuromodulator dbr:(2''S'')-1-[(2''S'')-2-<nowik...arbonyl]amino]-3-hydroxybutanoic_acid |
| dbp:imagefile |
Proctolin.svg (en) |
| dbp:imagesize |
250 (xsd:integer) |
| dbp:iupacname |
-2 (xsd:integer) |
| dbp:othernames |
(L)-Arginyl-(L)-tyrosyl-(L)-leucyl-(L)-prolyl-(L)-threonine; Arg-Tyr-Leu-Pro-Thr (en) |
| dbp:wikiPageUsesTemplate |
dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Cite_book dbt:Cite_journal dbt:Morefootnotes dbt:Reflist |
| dct:subject |
dbc:Pentapeptides dbc:Neuropeptides |
| gold:hypernym |
dbr:Neuropeptide |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:ChemicalCompound dbo:Protein yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 |
| rdfs:comment |
Das Proctolin (englisch synonym) bezeichnet eine aus fünf Aminosäuren bestehendes Neuropeptid (H-Arg-Tyr-Leu-Pro-Thr-OH), das bei Insekten für die neuromuskulären Synapsen der im Bereich des Enddarms als Neurotransmitter fungiert. Darüber hinaus ist Proctolin immunologisch auch im Zentralnervensystem von Insekten und sogar von Wirbeltieren als weit verbreitet nachzuweisen. Ihm wird eine generelle Neurotransmitterfunktion zugeschrieben. (de) Proctolin is a neuropeptide present in insects and crustaceans. It was first found in Periplaneta americana, a species of cockroach in 1975. Proctolin was extracted from 125,000 cockroaches and the Edman degradation was carried out on the sample to determine the amino acid sequence, which is Arg-Tyr-Leu-Pro-Thr. Proctolin was the first insect neuropeptide to be sequenced. Starratt and Brown identified it as a visceral muscle neurotransmitter. However, it now appears that there are many more functions of proctolin, and it is present in many more species. (en) |
| rdfs:label |
Proctolin (de) Proctolin (en) |
| owl:sameAs |
freebase:Proctolin wikidata:Proctolin dbpedia-de:Proctolin https://global.dbpedia.org/id/2157S |
| prov:wasDerivedFrom |
wikipedia-en:Proctolin?oldid=1100860260&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Proctolin.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Proctolin |
| is dbo:wikiPageWikiLink of |
dbr:Neuropeptide dbr:Cotesia_congregata dbr:Rhodnius_prolixus |
| is foaf:primaryTopic of |
wikipedia-en:Proctolin |
