| dbo:abstract |
Das Protein M ist ein Protein aus Mycoplasma genitalium, das Antikörper bindet. (de) Protein M (locus MG281) is an immunoglobulin-binding protein originally found on the cell surface of the human pathogenic bacterium Mycoplasma genitalium. It is presumably a universal antibody-binding protein, as it is known to be reactive against all antibody types tested so far. It is capable of preventing the antigen-antibody interaction due to its high binding affinity to any antibody. The Scripps Research Institute announced its discovery in 2014. It was detected from the bacterium while investigating its role in patients with a cancer, multiple myeloma. Homologous proteins are found in other Mycoplasma bacteria. Mycoplasma pneumoniae, another human pathogen, has a homolog termed IbpM (locus MPN400). (en) |
| dbo:symbol |
M_MG281 |
| dbo:wikiPageID |
43512319 (xsd:integer) |
| dbo:wikiPageLength |
8918 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1099532416 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Protein_A dbr:Protein_L dbr:Non-gonococcal_urethritis dbr:Antigen-antibody_interaction dbr:Binding_affinity dbr:KDa dbr:Protein_G dbr:Multiple_myeloma dbr:Mycoplasma dbr:Urethritis dbr:St_Mary's_Hospital,_London dbr:Pelvic_inflammatory_disease dbc:Bacterial_proteins dbc:Sexually_transmitted_diseases_and_infections dbr:Salt_bridge_(protein_and_supramolecular) dbc:Immune_system dbr:Hydrogen_bonds dbr:Antibodies dbr:Cervicitis dbr:Mycoplasma_genitalium dbr:Immune_system dbr:Mycoplasma_pneumoniae dbr:Van_der_Waals_interactions dbr:The_Scripps_Research_Institute dbr:Pathogenic_bacterium dbr:MIB-MIP |
| dbp:interpro |
IPR030943 (en) |
| dbp:name |
IgG-blocking protein M (en) Uncharacterized protein MG281 (en) |
| dbp:organism |
Mycoplasma genitalium ATCC 33530 (en) |
| dbp:symbol |
MG281 (en) M_MG281 (en) |
| dbp:uniprot |
P47523 (en) |
| dbp:wikiPageUsesTemplate |
dbt:! dbt:Citation_needed dbt:Distinguish dbt:Infobox_nonhuman_protein dbt:Reflist dbt:Short_description dbt:Pfam_box |
| dcterms:subject |
dbc:Bacterial_proteins dbc:Sexually_transmitted_diseases_and_infections dbc:Immune_system |
| gold:hypernym |
dbr:Protein |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 dbo:Protein |
| rdfs:comment |
Das Protein M ist ein Protein aus Mycoplasma genitalium, das Antikörper bindet. (de) Protein M (locus MG281) is an immunoglobulin-binding protein originally found on the cell surface of the human pathogenic bacterium Mycoplasma genitalium. It is presumably a universal antibody-binding protein, as it is known to be reactive against all antibody types tested so far. It is capable of preventing the antigen-antibody interaction due to its high binding affinity to any antibody. The Scripps Research Institute announced its discovery in 2014. It was detected from the bacterium while investigating its role in patients with a cancer, multiple myeloma. (en) |
| rdfs:label |
Protein M (de) Protein M (en) |
| owl:differentFrom |
dbr:M_protein_(Streptococcus) |
| owl:sameAs |
freebase:Protein M yago-res:Protein M wikidata:Protein M dbpedia-de:Protein M https://global.dbpedia.org/id/kk9h |
| prov:wasDerivedFrom |
wikipedia-en:Protein_M?oldid=1099532416&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:Protein_M |
| is dbo:wikiPageWikiLink of |
dbr:Immunoglobulin-binding_protein dbr:M_protein dbr:Mycoplasma_genitalium |
| is owl:differentFrom of |
dbr:M_protein_(Streptococcus) |
| is foaf:primaryTopic of |
wikipedia-en:Protein_M |