RAP6 (original) (raw)
RAP6 is the abbreviation for Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis. RAP6 was discovered by Alejandro Barbieri and his group of researchers (Christine Hunker, Adriana Galvis, Ivan Kruk, Hugo Giambini, Lina Torres and Maria Luisa Veisaga) working at Florida International University. This novel human protein has been reported to be involved in membrane trafficking. It has been shown that RAP6 has a guanine nucleotide exchange factor (GEF) activity specific to Rab5 and a GTPase activating protein (GAP) activity specific to RAS.
| Property | Value |
|---|---|
| dbo:abstract | RAP6 is the abbreviation for Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis. RAP6 was discovered by Alejandro Barbieri and his group of researchers (Christine Hunker, Adriana Galvis, Ivan Kruk, Hugo Giambini, Lina Torres and Maria Luisa Veisaga) working at Florida International University. This novel human protein has been reported to be involved in membrane trafficking. It has been shown that RAP6 has a guanine nucleotide exchange factor (GEF) activity specific to Rab5 and a GTPase activating protein (GAP) activity specific to RAS. The original GeneBank Identifications (GIs) have been published in the NCBI Nucleotide databases with GIs 77176718 and 77176720. Since then, many names have been coined to the validated protein such as RabGEF1, GeneID: 27342. RAP6 belongs to the family of the GAPVD1, GeneID: 26130 (en) |
| dbo:wikiPageExternalLink | https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi%3Fdb=nuccore&id=77176720 https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi%3Fdb=nucleotide&val=77176718 https://www.ncbi.nlm.nih.gov/sites/entrez%3Fdb=gene&cmd=Retrieve&list_uids=26130 https://www.ncbi.nlm.nih.gov/sites/entrez%3Fdb=gene&cmd=Retrieve&list_uids=27342 |
| dbo:wikiPageID | 14942693 (xsd:integer) |
| dbo:wikiPageLength | 1938 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1077740750 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Endocytosis dbc:Transport_proteins dbc:Cellular_processes dbr:Florida_International_University dbr:Protein dbr:Ras_superfamily dbr:Guanine_nucleotide_exchange_factor dbr:GTPase_activating_protein |
| dbp:wikiPageUsesTemplate | dbt:Reflist |
| dct:subject | dbc:Transport_proteins dbc:Cellular_processes |
| rdfs:comment | RAP6 is the abbreviation for Rab5-activating protein 6, a novel endosomal protein with a role in endocytosis. RAP6 was discovered by Alejandro Barbieri and his group of researchers (Christine Hunker, Adriana Galvis, Ivan Kruk, Hugo Giambini, Lina Torres and Maria Luisa Veisaga) working at Florida International University. This novel human protein has been reported to be involved in membrane trafficking. It has been shown that RAP6 has a guanine nucleotide exchange factor (GEF) activity specific to Rab5 and a GTPase activating protein (GAP) activity specific to RAS. (en) |
| rdfs:label | RAP6 (en) |
| owl:sameAs | wikidata:RAP6 https://global.dbpedia.org/id/4tXRo |
| prov:wasDerivedFrom | wikipedia-en:RAP6?oldid=1077740750&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:RAP6 |
| is dbo:wikiPageRedirects of | dbr:Rap6 |
| is dbo:wikiPageWikiLink of | dbr:Endocytosis dbr:Rap6 |
| is foaf:primaryTopic of | wikipedia-en:RAP6 |