dbo:abstract |
Rezeptortheorie ist ein Begriff aus der Pharmakologie. Sie erklärt die Wirkungen verschiedener Arzneimittel als Wechselwirkung von Pharmakomolekülen oder natürlichen Liganden mit Rezeptoren. (de) Receptor theory is the application of receptor models to explain drug behavior. Pharmacological receptor models preceded accurate knowledge of receptors by many years. John Newport Langley and Paul Ehrlich introduced the concept of a receptor that would mediate drug action at the beginning of the 20th century. Alfred Joseph Clark was the first to quantify drug-induced biological responses (specifically, f-mediated receptor activation). So far, nearly all of the quantitative theoretical modelling of receptor function has centred on ligand-gated ion channels and GPCRs. (en) |
dbo:wikiPageID |
13991735 (xsd:integer) |
dbo:wikiPageLength |
15389 (xsd:nonNegativeInteger) |
dbo:wikiPageRevisionID |
1123683680 (xsd:integer) |
dbo:wikiPageWikiLink |
dbr:Alfred_Joseph_Clark dbr:John_Newport_Langley dbr:Paul_Ehrlich dbr:GPCR dbr:Receptor_antagonist dbr:Protein_structure dbr:Dissociation_constant dbr:Agonist dbr:Agonists dbc:Biochemistry dbr:Everhardus_Jacobus_Ariëns dbc:Sensory_receptors dbr:Binding_sites dbr:Hill_equation_(biochemistry) dbr:Dose-response_relationship dbr:Receptor_(biochemistry) dbr:Archibald_Hill dbc:Pharmacology dbr:John_Gaddum dbr:Schild_regression dbr:Inverse_agonists dbr:Scientific_hypothesis dbr:Ligand-gated_ion_channels |
dbp:wikiPageUsesTemplate |
dbt:Reflist dbt:Short_description |
dct:subject |
dbc:Biochemistry dbc:Sensory_receptors dbc:Pharmacology |
gold:hypernym |
dbr:Application |
rdf:type |
dbo:Software yago:WikicatSensoryReceptors yago:BodyPart105220461 yago:Organ105297523 yago:Part109385911 yago:PhysicalEntity100001930 yago:SenseOrgan105299178 yago:Thing100002452 |
rdfs:comment |
Rezeptortheorie ist ein Begriff aus der Pharmakologie. Sie erklärt die Wirkungen verschiedener Arzneimittel als Wechselwirkung von Pharmakomolekülen oder natürlichen Liganden mit Rezeptoren. (de) Receptor theory is the application of receptor models to explain drug behavior. Pharmacological receptor models preceded accurate knowledge of receptors by many years. John Newport Langley and Paul Ehrlich introduced the concept of a receptor that would mediate drug action at the beginning of the 20th century. Alfred Joseph Clark was the first to quantify drug-induced biological responses (specifically, f-mediated receptor activation). So far, nearly all of the quantitative theoretical modelling of receptor function has centred on ligand-gated ion channels and GPCRs. (en) |
rdfs:label |
Rezeptortheorie (de) Receptor theory (en) |
owl:sameAs |
freebase:Receptor theory yago-res:Receptor theory wikidata:Receptor theory dbpedia-de:Receptor theory dbpedia-sh:Receptor theory dbpedia-sr:Receptor theory https://global.dbpedia.org/id/53mNi |
prov:wasDerivedFrom |
wikipedia-en:Receptor_theory?oldid=1123683680&ns=0 |
foaf:isPrimaryTopicOf |
wikipedia-en:Receptor_theory |
is dbo:knownFor of |
dbr:Paul_Ehrlich dbr:Everhardus_Jacobus_Ariëns |
is dbo:wikiPageWikiLink of |
dbr:Allosteric_regulation dbr:Paul_Ehrlich dbr:Reuptake_inhibitor dbr:Receptor_antagonist dbr:G_protein-coupled_receptor dbr:Agonist dbr:Everhardus_Jacobus_Ariëns dbr:Receptor_(biochemistry) dbr:TRPC6 dbr:P2Y_receptor |
is dbp:knownFor of |
dbr:Paul_Ehrlich |
is foaf:primaryTopic of |
wikipedia-en:Receptor_theory |