| dbo:abstract |
Ro48-8684 is a water-soluble benzodiazepine derivative developed by Hoffman-LaRoche in the 1990s, which was designed along with Ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice. (en) Il Ro48-8684 è uno psicofarmaco appartenente alla categoria delle imidazobenzodiazepine solubile in acqua sviluppato da Hoffmann-La Roche negli anni '90, che è stato progettato insieme a Ro48-6791 come sostituto migliorato del midazolam, ma alla fine ha dimostrato di avere pochi vantaggi rispetto al farmaco originario e non è stato introdotto nella pratica clinica. (it) |
| dbo:pubchem |
9866317 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Ro48-8684.svg?width=300 |
| dbo:wikiPageID |
25533820 (xsd:integer) |
| dbo:wikiPageLength |
2629 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1098691412 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Benzodiazepine dbr:Ro48-6791 dbc:Abandoned_drugs dbc:Fluoroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Lactams dbc:Imidazobenzodiazepines dbc:Oxazoles dbc:Hoffmann-La_Roche_brands dbr:Midazolam dbr:Hoffman-LaRoche |
| dbp:c |
22 (xsd:integer) |
| dbp:chemspiderid |
8042008 (xsd:integer) |
| dbp:f |
1 (xsd:integer) |
| dbp:h |
26 (xsd:integer) |
| dbp:iupacName |
3 (xsd:integer) |
| dbp:molecularWeight |
411.472000 (xsd:double) |
| dbp:n |
5 (xsd:integer) |
| dbp:o |
2 (xsd:integer) |
| dbp:pubchem |
9866317 (xsd:integer) |
| dbp:smiles |
CCCNCCC (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
YKKLHEHNUYCLQQ-UHFFFAOYSA-N (en) |
| dbp:verifiedrevid |
451550070 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:width |
242 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:GABAAR_PAMs dbt:Reflist dbt:Short_description dbt:Drugbankcite dbt:Benzodiazepines dbt:Sedative-stub |
| dct:subject |
dbc:Abandoned_drugs dbc:Fluoroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Lactams dbc:Imidazobenzodiazepines dbc:Oxazoles dbc:Hoffmann-La_Roche_brands |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatBenzodiazepines yago:Agent114778436 yago:Benzodiazepine102830852 yago:CausalAgent100007347 yago:Drug103247620 yago:DrugOfAbuse103248958 yago:Matter100020827 yago:Medicine103740161 yago:MinorTranquilizer103771443 yago:MuscleRelaxant103800001 yago:PhysicalEntity100001930 yago:PsychotropicAgent104017429 yago:Relaxant104072811 dbo:Drug yago:Sedative-hypnotic104166841 yago:Sedative104166553 yago:Substance100020090 yago:Tranquilizer104470232 |
| rdfs:comment |
Ro48-8684 is a water-soluble benzodiazepine derivative developed by Hoffman-LaRoche in the 1990s, which was designed along with Ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice. (en) Il Ro48-8684 è uno psicofarmaco appartenente alla categoria delle imidazobenzodiazepine solubile in acqua sviluppato da Hoffmann-La Roche negli anni '90, che è stato progettato insieme a Ro48-6791 come sostituto migliorato del midazolam, ma alla fine ha dimostrato di avere pochi vantaggi rispetto al farmaco originario e non è stato introdotto nella pratica clinica. (it) |
| rdfs:label |
Ro48-8684 (it) Ro48-8684 (en) |
| owl:sameAs |
freebase:Ro48-8684 yago-res:Ro48-8684 wikidata:Ro48-8684 dbpedia-it:Ro48-8684 dbpedia-sh:Ro48-8684 dbpedia-sr:Ro48-8684 https://global.dbpedia.org/id/4uEBw |
| prov:wasDerivedFrom |
wikipedia-en:Ro48-8684?oldid=1098691412&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Ro48-8684.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Ro48-8684 |
| is dbo:wikiPageWikiLink of |
dbr:List_of_benzodiazepines |
| is foaf:primaryTopic of |
wikipedia-en:Ro48-8684 |
