Scedosporiosis (original) (raw)
Scedosporiosis is the general name for any mycosis - i.e., fungal infection - caused by a fungus from the genus Scedosporium. Current population-based studies suggest Scedosporium prolificans (also known and recently more commonly referred to as Lomentospora prolificans) and Scedosporium apiospermum to be among the most common infecting agents from the genus, although infections caused by other members thereof are not unheard of. The latter is an asexual form (anamorph) of another fungus, Pseudallescheria boydii. The former is a “black yeast” (aka dematiaceous fungus), currently not characterized as well, although both of them have been described as saprophytes.
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| dbo:abstract | Scedosporiosis is the general name for any mycosis - i.e., fungal infection - caused by a fungus from the genus Scedosporium. Current population-based studies suggest Scedosporium prolificans (also known and recently more commonly referred to as Lomentospora prolificans) and Scedosporium apiospermum to be among the most common infecting agents from the genus, although infections caused by other members thereof are not unheard of. The latter is an asexual form (anamorph) of another fungus, Pseudallescheria boydii. The former is a “black yeast” (aka dematiaceous fungus), currently not characterized as well, although both of them have been described as saprophytes. The fungi of this genus are more and more recognized as significant human pathogens. S. apiospermum is described as an emerging and even an “underrated” opportunistic pathogen. It was reported in a 2003 US study that Scedosporiosis had been associated with 25% of all non-Aspergillus fungal infections for organ transplant patients. In a similar 2005 study scedosporal infections caused a 58% mortality rate for transplant recipients affected with it. Among the patients with cystic fibrosis, it is the second most common fungal infection. Moreover, a certain difficulty has been reported with correctly identifying the pathogen as, for example, scedosporal infections are in some cases almost indistinguishable from infections with other filamentous fungi, like the already-mentioned Aspergillus – this difficulty could have potentially contributed to the “underrating” of the pathogen. All of this, along with the wide resistance possessed by the pathogens to the antifungal therapies currently in medical use, presents the increased interest for researchers to further study the scedoporal infections and develop treatments. (en) |
| dbo:icd10 | B48.7 |
| dbo:medicalCause | dbr:Scedosporium_prolificans dbr:Scedosporium_apiospermum |
| dbo:orpha | 449280 |
| dbo:treatment | dbr:Antifungal |
| dbo:wikiPageID | 46828613 (xsd:integer) |
| dbo:wikiPageLength | 23300 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1102249492 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Cancer dbr:Amputation dbr:Saprotrophic_nutrition dbr:Scedosporium_prolificans dbr:Mortality_rate dbr:Muscle dbr:Bone dbr:Antifungal dbr:Retina dbr:Cystic_fibrosis dbr:Voriconazole dbr:Mold dbr:Pseudallescheria_boydii dbr:Genus dbr:Osteomyelitis dbr:Pseudomonas_aeruginosa dbr:Pyrimidine_biosynthesis dbr:Fungus dbr:Brain_abscess dbr:Morphology_(biology) dbr:Mycosis dbr:Conidium dbr:Cornea dbr:Leukemia dbr:Emerging_infectious_disease dbr:Keratitis dbr:Subcutaneous_tissue dbr:HIV dbr:Joint dbr:Amphotericin_B dbc:Animal_fungal_diseases dbr:Eumycetoma dbr:Dihydroorotate_dehydrogenase dbr:Fosmanogepix dbr:Rib dbr:Hematopoietic_stem_cell_transplantation dbr:Isavuconazonium dbr:Terbinafine dbr:Aspergillosis dbr:Acrophialophora_fusispora dbr:Black_yeast dbr:Aspergillus dbc:Fungal_diseases dbr:Posaconazole dbr:Scedosporium_apiospermum dbr:Ibrexafungerp dbr:Micafungin dbr:Organ_(anatomy) dbr:Organ_transplantation dbr:Ravuconazole dbr:Minimum_inhibitory_concentration dbr:Infectious_disease_(medical_speciality) dbr:Neutropenia dbr:Immunodeficiency dbr:Immunosuppression dbr:Mycetoma dbr:Scedosporium dbr:Photophobia dbr:Phaeohyphomycosis dbr:Sternum dbr:Anidulafungin dbr:Near-drowning |
| dbp:causes | dbr:Scedosporium_prolificans dbr:Scedosporium_apiospermum |
| dbp:field | dbr:Mycosis dbr:Infectious_disease_(medical_speciality) |
| dbp:icd | B48.7 (en) |
| dbp:orphanet | 449280 (xsd:integer) |
| dbp:risks | dbr:Cancer dbr:Neutropenia dbr:Immunodeficiency |
| dbp:treatment | antifungal drugs, surgery (en) |
| dbp:types | localized, disseminated (en) |
| dbp:wikiPageUsesTemplate | dbt:Cn dbt:Infobox_medical_condition_(new) dbt:Medical_resources dbt:PAGENAME dbt:Reflist |
| dct:subject | dbc:Animal_fungal_diseases dbc:Fungal_diseases |
| gold:hypernym | dbr:Infection |
| rdf:type | owl:Thing wikidata:Q12136 dbo:Disease |
| rdfs:comment | Scedosporiosis is the general name for any mycosis - i.e., fungal infection - caused by a fungus from the genus Scedosporium. Current population-based studies suggest Scedosporium prolificans (also known and recently more commonly referred to as Lomentospora prolificans) and Scedosporium apiospermum to be among the most common infecting agents from the genus, although infections caused by other members thereof are not unheard of. The latter is an asexual form (anamorph) of another fungus, Pseudallescheria boydii. The former is a “black yeast” (aka dematiaceous fungus), currently not characterized as well, although both of them have been described as saprophytes. (en) |
| rdfs:label | Scedosporiosis (en) |
| owl:sameAs | freebase:Scedosporiosis wikidata:Scedosporiosis https://global.dbpedia.org/id/2Mxwt |
| prov:wasDerivedFrom | wikipedia-en:Scedosporiosis?oldid=1102249492&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Scedosporiosis |
| is dbo:wikiPageWikiLink of | dbr:Orotomide dbr:Fungal_infection dbr:Scedosporium |
| is foaf:primaryTopic of | wikipedia-en:Scedosporiosis |