Alphavirus (original) (raw)

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Alphavirus je rod virů, který náleží k čeledi Togaviridae. Jde o viry lidí, savců, ptáků, moskytů a vačnatců, které jsou přenášeny hmyzem. Způsobují encefalitidu, horečky a bolesti. jsou celosvětově rozšířené, avšak antivirotikum neexistuje.

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dbo:abstract Alphavirus je rod virů, který náleží k čeledi Togaviridae. Jde o viry lidí, savců, ptáků, moskytů a vačnatců, které jsou přenášeny hmyzem. Způsobují encefalitidu, horečky a bolesti. jsou celosvětově rozšířené, avšak antivirotikum neexistuje. (cs) فيروس ألفا (بالإنجليزية: Alphavirus)‏ هي مجموعة من الفيروسات تنمتي إلى الفيروسات الطخائية. (ar) Alphavirus is a genus of RNA viruses, the sole genus in the Togaviridae family. Alphaviruses belong to group IV of the Baltimore classification of viruses, with a positive-sense, single-stranded RNA genome. There are 32 alphaviruses, which infect various vertebrates such as humans, rodents, fish, birds, and larger mammals such as horses, as well as invertebrates. Alphaviruses that could infect both vertebrates and arthropods are referred dual-host alphaviruses, while insect-specific alphaviruses such as Eilat virus and Yada yada virus are restricted to their competent arthropod vector. Transmission between species and individuals occurs mainly via mosquitoes, making the alphaviruses a member of the collection of arboviruses – or arthropod-borne viruses. Alphavirus particles are enveloped, have a 70 nm diameter, tend to be spherical (although slightly pleomorphic), and have a 40 nm isometric nucleocapsid. (en) Alphavirus (früher: Arbovirus A) ist eine Virus-Gattung der Togaviridae. (de) Los alfavirus son un grupo de virus ARN monocatenario positivo, se incluyen en la familia Togaviridae. Existen numerosas especies de alphavirus que pueden provocar enfermedad en el hombre y otros animales vertebrados, como caballos, roedores, peces y aves. La transmisión ocurre generalmente por picadura de insectos, principalmente mosquitos.​​​ (es) En termes de biologie et d’immunologie, les alphavirus appartiennent au groupe IV des virus et à la famille des togaviridae, selon le système de classification basé sur la composition du génome viral présenté par David Baltimore en 1971. Les Alphavirus, comme tous les autres virus du groupe IV ont un génome constitué d’un seul brin d’ARN à polarité positive. Il existe 27 alphavirus, capables d'infecter divers vertébrés comme les humains, les rongeurs, les oiseaux et les grands mammifères tels que les chevaux ainsi que les invertébrés. La transmission entre individus et entre espèces se fait par l’intermédiaire des moustiques ce qui permet de ranger les alphavirus dans le groupe des arbovirus - ou arthropode-borne virus . Les particules d’Alphavirus sont enveloppées et ont un diamètre de 70 nm, presque sphériques (bien que légèrement pléomorphes), et possèdent une nucléocapside isométrique de 40 nm. (fr) Alphavirus (nella letteratura in lingua italiana talora Alfavirus) è un genere di virus ad RNA a singolo filamento positivo, unico membro della famiglia dei Togaviridae, di medie dimensioni, forma rotondeggiante, nucleocapside a simmetria icosaedrica avvolto da membrana lipoproteica, in grado di infettare numerosi vertebrati per mezzo di artropodi. Ubiquitari e distribuiti in sette gruppi sierologici, gli Alphavirus determinano due gruppi di patologie: encefaliti e sindromi febbrili con eruzioni cutanee e poliartriti. (it) Alfavirusen är ett släkte av virus som tillhör familjen . Det finns 25 olika slags alfavirus och man har bevisat att 11 av dem är smittbara till människor. Överföringen av viruset sker oftast via myggor, vilket då gör alfavirusen till ett arbovirus (virus som sprids med hjälp av leddjur, ex. myggor och fästingar). (sv) Alphavirus é um gênero de vírus RNAss de sentido positivo, esféricos, de 65-70nm, com envelope e responsáveis por diversos tipos de encefalites e síndromes febril com dor articular, como o Chikungunya, transmitidos por mosquitos, como do gênero Aedes. Causam doenças tanto em humanos e diversos outros animais. (pt) Alphavirus — род РНК-вирусов, единственный род в семействе . Альфавирусы принадлежат к группе IV Балтиморской классификации вирусов с геномом (+)РНК. Существует 32 альфавируса, которые заражают различных позвоночных, таких как люди, грызуны, рыбы, птицы и более крупных млекопитающих, таких как лошади, а также беспозвоночных. Альфавирусы, которые могут инфицировать как позвоночных, так и членистоногих, называются альфавирусами с двойным хозяином, в то время как альфавирусы, специфичные для насекомых, такие как вирус Эйлат и вирус Яда-яда, ограничены их компетентным переносчиком из членистоногих. Передача между видами и отдельными особями происходит в основном через комаров, что делает альфавирусы членом коллекции арбовирусов или вирусов, переносимых членистоногими. Частицы альфавируса имеют оболочку диаметром в 70 нм, сферической формы (существует некоторый плеоморфизм). Нуклеокапсид изометрический 40 нм в диаметре. (ru)
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dbp:caption Mapping the E2 glycoprotein of alphaviruses (en) Crystal structure of the homotrimer of fusion glycoprotein E1 from Semliki Forest virus (en)
dbp:image Alphavirus.png (en)
dbp:image2Alt A computer-generated model of the surface of an "Alphavirus" derived by cryoelectron microscopy. The spike-like structures on the virion surface are trimers composed of heterodimers of the virion surface glycoproteins E1 and E2. These spikes are used by the virus to attach to susceptible animal cells (en)
dbp:image2Caption A computer-generated model of the surface of an Alphavirus derived by cryoelectron microscopy. The spike-like structures on the virion surface are trimers composed of heterodimers of the virion surface Glycoproteins E1 and E2. These spikes are used by the virus to attach to susceptible animal cells (en)
dbp:imageCaption Structure and genome of an alphavirus (en)
dbp:interpro IPR000936 (en) IPR002533 (en) IPR002548 (en)
dbp:name Alpha_E1_glycop (en) Alpha_E2_glycop (en) Alpha_E3_glycop (en)
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dbp:pfam PF00943 (en) PF01563 (en) PF01589 (en)
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dbp:subdivision * Aura virus * Barmah Forest virus * Bebaru virus * Caaingua virus * Cabassou virus * Chikungunya virus * Eastern equine encephalitis virus * Eilat virus * Everglades virus * Fort Morgan virus * Getah virus * Highlands J virus * Madariaga virus * Mayaro virus * Middelburg virus * Mosso das Pedras virus * Mucambo virus * Ndumu virus * O'nyong'nyong virus * Pixuna virus * Rio Negro virus * Ross River virus * Salmon pancreas disease virus * Semliki Forest virus * Sindbis virus * Southern elephant seal virus * Tonate virus * Trocara virus * Una virus * Venezuelan equine encephalitis virus * Western equine encephalitis virus * Whataroa virus (en)
dbp:subdivisionRanks Species (en)
dbp:symbol Alpha_E1_glycop (en) Alpha_E2_glycop (en) Alpha_E3_glycop (en)
dbp:taxon Alphavirus (en)
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rdfs:comment Alphavirus je rod virů, který náleží k čeledi Togaviridae. Jde o viry lidí, savců, ptáků, moskytů a vačnatců, které jsou přenášeny hmyzem. Způsobují encefalitidu, horečky a bolesti. jsou celosvětově rozšířené, avšak antivirotikum neexistuje. (cs) فيروس ألفا (بالإنجليزية: Alphavirus)‏ هي مجموعة من الفيروسات تنمتي إلى الفيروسات الطخائية. (ar) Alphavirus (früher: Arbovirus A) ist eine Virus-Gattung der Togaviridae. (de) Los alfavirus son un grupo de virus ARN monocatenario positivo, se incluyen en la familia Togaviridae. Existen numerosas especies de alphavirus que pueden provocar enfermedad en el hombre y otros animales vertebrados, como caballos, roedores, peces y aves. La transmisión ocurre generalmente por picadura de insectos, principalmente mosquitos.​​​ (es) Alphavirus (nella letteratura in lingua italiana talora Alfavirus) è un genere di virus ad RNA a singolo filamento positivo, unico membro della famiglia dei Togaviridae, di medie dimensioni, forma rotondeggiante, nucleocapside a simmetria icosaedrica avvolto da membrana lipoproteica, in grado di infettare numerosi vertebrati per mezzo di artropodi. Ubiquitari e distribuiti in sette gruppi sierologici, gli Alphavirus determinano due gruppi di patologie: encefaliti e sindromi febbrili con eruzioni cutanee e poliartriti. (it) Alfavirusen är ett släkte av virus som tillhör familjen . Det finns 25 olika slags alfavirus och man har bevisat att 11 av dem är smittbara till människor. Överföringen av viruset sker oftast via myggor, vilket då gör alfavirusen till ett arbovirus (virus som sprids med hjälp av leddjur, ex. myggor och fästingar). (sv) Alphavirus é um gênero de vírus RNAss de sentido positivo, esféricos, de 65-70nm, com envelope e responsáveis por diversos tipos de encefalites e síndromes febril com dor articular, como o Chikungunya, transmitidos por mosquitos, como do gênero Aedes. Causam doenças tanto em humanos e diversos outros animais. (pt) Alphavirus is a genus of RNA viruses, the sole genus in the Togaviridae family. Alphaviruses belong to group IV of the Baltimore classification of viruses, with a positive-sense, single-stranded RNA genome. There are 32 alphaviruses, which infect various vertebrates such as humans, rodents, fish, birds, and larger mammals such as horses, as well as invertebrates. Alphaviruses that could infect both vertebrates and arthropods are referred dual-host alphaviruses, while insect-specific alphaviruses such as Eilat virus and Yada yada virus are restricted to their competent arthropod vector. Transmission between species and individuals occurs mainly via mosquitoes, making the alphaviruses a member of the collection of arboviruses – or arthropod-borne viruses. Alphavirus particles are enveloped, (en) En termes de biologie et d’immunologie, les alphavirus appartiennent au groupe IV des virus et à la famille des togaviridae, selon le système de classification basé sur la composition du génome viral présenté par David Baltimore en 1971. Les Alphavirus, comme tous les autres virus du groupe IV ont un génome constitué d’un seul brin d’ARN à polarité positive. Il existe 27 alphavirus, capables d'infecter divers vertébrés comme les humains, les rongeurs, les oiseaux et les grands mammifères tels que les chevaux ainsi que les invertébrés. La transmission entre individus et entre espèces se fait par l’intermédiaire des moustiques ce qui permet de ranger les alphavirus dans le groupe des arbovirus - ou arthropode-borne virus . Les particules d’Alphavirus sont enveloppées et ont un diamètre de 70 (fr) Alphavirus — род РНК-вирусов, единственный род в семействе . Альфавирусы принадлежат к группе IV Балтиморской классификации вирусов с геномом (+)РНК. Существует 32 альфавируса, которые заражают различных позвоночных, таких как люди, грызуны, рыбы, птицы и более крупных млекопитающих, таких как лошади, а также беспозвоночных. Альфавирусы, которые могут инфицировать как позвоночных, так и членистоногих, называются альфавирусами с двойным хозяином, в то время как альфавирусы, специфичные для насекомых, такие как вирус Эйлат и вирус Яда-яда, ограничены их компетентным переносчиком из членистоногих. Передача между видами и отдельными особями происходит в основном через комаров, что делает альфавирусы членом коллекции арбовирусов или вирусов, переносимых членистоногими. Частицы альфавируса имею (ru)
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