Tybamate (original) (raw)
Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family. It is a prodrug for meprobamate in the same way as the better known drug carisoprodol. It has liver enzyme inducing effects similar to those of phenobarbital but much weaker. As the trade name Tybatran (Robins), it was formerly available in capsules of 125, 250, and 350 mg, taken 3 or 4 times a day for a total daily dosage of 750 mg to 2 g. The plasma half-life of the drug is three hours. At high doses in combination with phenothiazines, it could produce convulsions.
| Property | Value |
|---|---|
| dbo:abstract | Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family. It is a prodrug for meprobamate in the same way as the better known drug carisoprodol. It has liver enzyme inducing effects similar to those of phenobarbital but much weaker. As the trade name Tybatran (Robins), it was formerly available in capsules of 125, 250, and 350 mg, taken 3 or 4 times a day for a total daily dosage of 750 mg to 2 g. The plasma half-life of the drug is three hours. At high doses in combination with phenothiazines, it could produce convulsions. (en) Tybamat, summaformel C13H26N2O4, är ett lugnande och sömngivande preparat. Preparatet patententerades 1960. Tybamat är en prodrog för meprobamat, i likhet med karisoprodol. Tybamat är narkotikaklassat i Sverige, ingående i förteckning V, vilket innebär att det inte omfattas av internationella narkotikakonventioner. (sv) |
| dbo:casNumber | 4268-36-4 |
| dbo:fdaUniiCode | 3875LLL8M8 |
| dbo:kegg | D06260 |
| dbo:pubchem | 20266 |
| dbo:thumbnail | wiki-commons:Special:FilePath/Tybamate.png?width=300 |
| dbo:wikiPageID | 14344447 (xsd:integer) |
| dbo:wikiPageLength | 3444 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1082934190 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Carisoprodol dbc:Carbamates dbc:GABAA_receptor_positive_allosteric_modulators dbc:Prodrugs dbr:Anxiolytic dbr:Prodrug dbc:Anxiolytics dbr:Carbamate dbr:International_Nonproprietary_Name dbr:Phenobarbital dbr:Phenothiazine dbr:Meprobamate dbr:Wyeth |
| dbp:atcPrefix | none (en) |
| dbp:c | 13 (xsd:integer) |
| dbp:casNumber | 4268 (xsd:integer) |
| dbp:chemspiderid | 19092 (xsd:integer) |
| dbp:h | 26 (xsd:integer) |
| dbp:iupacName | [2--2-methylpentyl] N-butylcarbamate (en) |
| dbp:kegg | D06260 (en) |
| dbp:n | 2 (xsd:integer) |
| dbp:o | 4 (xsd:integer) |
| dbp:pubchem | 20266 (xsd:integer) |
| dbp:smiles | CCCCNCOCCCOCN (en) |
| dbp:stdinchi | 1 (xsd:integer) |
| dbp:stdinchikey | PRBORDFJHHAISJ-UHFFFAOYSA-N (en) |
| dbp:unii | 3875 (xsd:integer) |
| dbp:verifiedfields | changed (en) |
| dbp:verifiedrevid | 447997597 (xsd:integer) |
| dbp:watchedfields | changed (en) |
| dbp:width | 200 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Drugbox dbt:GABAAR_PAMs dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Anxiolytics dbt:Anxiolytic-stub |
| dcterms:subject | dbc:Carbamates dbc:GABAA_receptor_positive_allosteric_modulators dbc:Prodrugs dbc:Anxiolytics |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatCarbamates yago:Abstraction100002137 yago:Carbamate114792281 yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Salt115010703 yago:Substance100019613 |
| rdfs:comment | Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family. It is a prodrug for meprobamate in the same way as the better known drug carisoprodol. It has liver enzyme inducing effects similar to those of phenobarbital but much weaker. As the trade name Tybatran (Robins), it was formerly available in capsules of 125, 250, and 350 mg, taken 3 or 4 times a day for a total daily dosage of 750 mg to 2 g. The plasma half-life of the drug is three hours. At high doses in combination with phenothiazines, it could produce convulsions. (en) Tybamat, summaformel C13H26N2O4, är ett lugnande och sömngivande preparat. Preparatet patententerades 1960. Tybamat är en prodrog för meprobamat, i likhet med karisoprodol. Tybamat är narkotikaklassat i Sverige, ingående i förteckning V, vilket innebär att det inte omfattas av internationella narkotikakonventioner. (sv) |
| rdfs:label | Tybamate (en) Tybamat (sv) |
| owl:sameAs | freebase:Tybamate yago-res:Tybamate wikidata:Tybamate dbpedia-sh:Tybamate dbpedia-sr:Tybamate dbpedia-sv:Tybamate https://global.dbpedia.org/id/4wU7M |
| prov:wasDerivedFrom | wikipedia-en:Tybamate?oldid=1082934190&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Tybamate.png |
| foaf:isPrimaryTopicOf | wikipedia-en:Tybamate |
| is dbo:wikiPageWikiLink of | dbr:Carisoprodol dbr:Depressant dbr:Mebutamate dbr:Physical_dependence dbr:Carbamate dbr:C13H26N2O4 dbr:Meprobamate dbr:Lorbamate dbr:List_of_drugs:_Trj–Tz |
| is foaf:primaryTopic of | wikipedia-en:Tybamate |
