| dbo:abstract |
Vernolepin je seskviterpenový lakton vyskytující se v plodech rostliny . Snižuje srážlivost krve a také způsobuje nevratnou inhibici DNA polymerázy, v důsledku čehož má protinádorové účinky. (cs) Vernolepin is a sesquiterpene lactone isolated from the dried fruit of Vernonia amygdalina. It shows platelet anti-aggregating properties and is also an irreversible DNA polymerase inhibitor, hence may have antitumor properties. (en) |
| dbo:alternativeName |
Vernolepin (en) |
| dbo:iupacName |
(3aR,4S,5aR,9aR,9bR)-5a-Ethenyl-4-hydroxy-3,9-dimethylideneoctahydro-2H-furo[2,3-f][2]benzopyran-2,8(3H)-dione (en) |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Vernolepin.svg?width=300 |
| dbo:wikiPageID |
38300596 (xsd:integer) |
| dbo:wikiPageLength |
2502 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1041092341 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbc:DNA_polymerase_inhibitors dbr:DNA_polymerase dbc:Alkene_derivatives dbc:Secondary_alcohols dbc:Sesquiterpene_lactones dbr:C15H16O5 dbr:Antitumor dbr:Vernonia_amygdalina dbr:Sesquiterpene_lactone |
| dbp:imagefile |
Vernolepin.svg (en) |
| dbp:imagesize |
160 (xsd:integer) |
| dbp:othernames |
Vernolepin (en) |
| dbp:pin |
-5 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Chembox dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Organic-compound-stub dbt:Reflist dbt:Cascite dbt:Fdacite |
| dcterms:subject |
dbc:DNA_polymerase_inhibitors dbc:Alkene_derivatives dbc:Secondary_alcohols dbc:Sesquiterpene_lactones |
| gold:hypernym |
dbr:Lactone |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:WikicatOxygenHeterocycles yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:HeterocyclicCompound115025397 yago:Material114580897 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:ChemicalCompound yago:Substance100019613 |
| rdfs:comment |
Vernolepin je seskviterpenový lakton vyskytující se v plodech rostliny . Snižuje srážlivost krve a také způsobuje nevratnou inhibici DNA polymerázy, v důsledku čehož má protinádorové účinky. (cs) Vernolepin is a sesquiterpene lactone isolated from the dried fruit of Vernonia amygdalina. It shows platelet anti-aggregating properties and is also an irreversible DNA polymerase inhibitor, hence may have antitumor properties. (en) |
| rdfs:label |
Vernolepin (cs) Vernolepin (en) |
| owl:sameAs |
freebase:Vernolepin yago-res:Vernolepin wikidata:Vernolepin dbpedia-cs:Vernolepin https://global.dbpedia.org/id/4xEUm |
| prov:wasDerivedFrom |
wikipedia-en:Vernolepin?oldid=1041092341&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Vernolepin.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Vernolepin |
| is dbo:wikiPageWikiLink of |
dbr:Iodolactonization dbr:Lactone dbr:C15H16O5 |
| is foaf:primaryTopic of |
wikipedia-en:Vernolepin |
