| dbo:abstract |
Vesicular transport adaptor proteins are proteins involved in forming complexes that function in the trafficking of molecules from one subcellular location to another. These complexes concentrate the correct cargo molecules in vesicles that bud or extrude off of one organelle and travel to another location, where the cargo is delivered. While some of the details of how these adaptor proteins achieve their trafficking specificity has been worked out, there is still much to be learned. There are several human disorders associated with defects in components of these complexes including Alzheimer's and Parkinson's diseases. (en) As proteínas adaptadoras do transporte vesicular são proteínas envolvidas na formação de complexos que funcionam no de moléculas duma localização subcelular para outra. Estes complexos funcionam concentrando as moléculas correctas de carregamento nas vesículas de transporte que se invaginam ou extrudem de um organelo e viajam para outro lugar, onde o carregamento será entregue. Conhecem-se alguns detalhes sobre como estas proteínas adaptadoras mostram a sua especificidade de tráfico, mas ainda existe muito o que aprender. Vários trastornos humanos estão associados a defeitos nos componentes destes complexos, como o alzheimer e o parkinson. (pt) |
| dbo:thumbnail |
wiki-commons:Special:FilePath/AdaptorsOverviewc.jpg?width=300 |
| dbo:wikiPageExternalLink |
https://www.youtube.com/watch%3Fv=Ud2OtgwEs6E https://www.youtube.com/watch%3Fv=l4zhPvA5Qhc https://www.youtube.com/watch%3Fv=m-yuJz7ZEZw http://onlinelibrary.wiley.com/enhanced/figures/doi/10.1111/tra.12335%23figure-viewer-tra12335-fig-0005 http://onlinelibrary.wiley.com/store/10.1111/tra.12335/asset/image_n/tra12335-gra-0001.png%3Fv=1&s=64fcacd5ca500165364fc38f7bd5110edb5a9332 https://www.science.org/doi/full/10.1126/science.aab1121 https://d2ufo47lrtsv5s.cloudfront.net/content/sci/349/6244/195/F1.large.jpg https://www.youtube.com/watch%3Fv=1y9iQn_manI&t=8m12s |
| dbo:wikiPageID |
5884194 (xsd:integer) |
| dbo:wikiPageLength |
21210 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1095724808 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Endocytosis dbr:Endomembrane_system dbr:Endoplasmic_reticulum dbr:List_of_adaptins dbr:MEDNIK_syndrome dbr:Membrane_vesicle_trafficking dbr:SPG15 dbr:Beta dbr:DAB1 dbr:Vesicle_(biology_and_chemistry) dbr:Dynamin dbr:Intracellular_transport dbr:Sigma dbr:Nuclear_pore dbc:Cell_biology dbc:Protein_families dbr:NUMB_(gene) dbr:Clathrin dbr:Fungi dbr:Gamma dbr:Most_recent_common_ancestor dbr:Mu_(letter) dbr:Epsilon dbr:Epsin dbr:Approximation dbr:Leucine dbr:Lipids dbr:Delta_(letter) dbr:Synapse dbr:COPI dbr:COPII dbr:Cell_(biology) dbr:Tyrosine dbr:Clathrin_adaptor_proteins dbr:DAB2 dbr:Amino_acid dbc:Molecular_evolution dbc:Protein_complexes dbr:Dalton_(unit) dbr:Alpha dbr:Alzheimer's_disease dbr:Eukaryote dbr:Parkinson's_disease dbr:Golgi_apparatus dbr:Kilo- dbr:Protein_domain dbr:Protein dbr:AP180 dbr:ARF1 dbr:Hereditary_spastic_paraplegia dbr:Hermansky–Pudlak_syndrome dbr:Isoleucine dbr:Cranio-lenticulo-sutural_dysplasia dbr:Hypercholesterolemia dbr:AP2_adaptor_complex dbc:Vesicular_transport_proteins dbc:Cell_anatomy dbc:Organelles dbr:Kai_Simons dbr:Biogenesis_of_lysosome-related_organelles_complex_1 dbr:Coatomer dbr:Collagen dbr:Heterotetramer dbr:Translation_(biology) dbr:Zeta dbr:Dominance_(genetics) dbr:Autoimmune_disease dbr:Phosphatidylinositol_4,5-bisphosphate dbr:Phosphotyrosine-binding_domain dbr:Hydrophobic dbr:Opisthokont dbr:Organelle dbr:Organelles dbr:Lumen_(anatomy) dbr:SNARE_(protein) dbr:Low-density_lipoprotein_receptor_adapter_protein_1 dbr:Exomer dbr:Lipid_rafts dbr:Molecular_evolution dbr:Phosphorylation dbr:Retromer dbr:SPG11 dbr:Aspartic dbr:Muniscin dbr:ANTH dbr:Glutamic dbr:File:5APsAndCOPIFc.jpg dbr:File:APsCOPITSETc.jpg dbr:File:AdaptorsOverviewc.jpg dbr:File:B2appendEps15c.jpg dbr:File:CCVprodTimec.jpg dbr:File:COPIItubec.jpg dbr:File:CoatedVesiclec.jpg dbr:File:EndoERGICcompc.jpg dbr:File:PhosphoControlc.jpg dbr:File:TSETapsCOPIearlyEVOc.jpg dbr:File:TSETapsCOPIevoc.jpg |
| dbp:wikiPageUsesTemplate |
dbt:Clear dbt:Div_col dbt:Div_col_end dbt:Efn dbt:Gallery dbt:Notelist dbt:Reflist dbt:See_also |
| dcterms:subject |
dbc:Cell_biology dbc:Protein_families dbc:Molecular_evolution dbc:Protein_complexes dbc:Vesicular_transport_proteins dbc:Cell_anatomy dbc:Organelles |
| rdf:type |
owl:Thing |
| rdfs:comment |
Vesicular transport adaptor proteins are proteins involved in forming complexes that function in the trafficking of molecules from one subcellular location to another. These complexes concentrate the correct cargo molecules in vesicles that bud or extrude off of one organelle and travel to another location, where the cargo is delivered. While some of the details of how these adaptor proteins achieve their trafficking specificity has been worked out, there is still much to be learned. (en) As proteínas adaptadoras do transporte vesicular são proteínas envolvidas na formação de complexos que funcionam no de moléculas duma localização subcelular para outra. Estes complexos funcionam concentrando as moléculas correctas de carregamento nas vesículas de transporte que se invaginam ou extrudem de um organelo e viajam para outro lugar, onde o carregamento será entregue. Conhecem-se alguns detalhes sobre como estas proteínas adaptadoras mostram a sua especificidade de tráfico, mas ainda existe muito o que aprender. (pt) |
| rdfs:label |
Proteína adaptadora do transporte vesicular (pt) Vesicular transport adaptor protein (en) |
| rdfs:seeAlso |
dbr:Clathrin_adaptor_protein |
| owl:sameAs |
wikidata:Vesicular transport adaptor protein dbpedia-gl:Vesicular transport adaptor protein dbpedia-pt:Vesicular transport adaptor protein https://global.dbpedia.org/id/2qRJa yago-res:Vesicular transport adaptor protein |
| prov:wasDerivedFrom |
wikipedia-en:Vesicular_transport_adaptor_protein?oldid=1095724808&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/5APsAndCOPIFc.jpg wiki-commons:Special:FilePath/APsCOPITSETc.jpg wiki-commons:Special:FilePath/AdaptorsOverviewc.jpg wiki-commons:Special:FilePath/B2appendEps15c.jpg wiki-commons:Special:FilePath/CCVprodTimec.jpg wiki-commons:Special:FilePath/COPIItubec.jpg wiki-commons:Special:FilePath/CoatedVesiclec.jpg wiki-commons:Special:FilePath/EndoERGICcompc.jpg wiki-commons:Special:FilePath/PhosphoControlc.jpg wiki-commons:Special:FilePath/SynapseSchematic_lines.svg wiki-commons:Special:FilePath/TSETapsCOPIearlyEVOc.jpg wiki-commons:Special:FilePath/TSETapsCOPIevoc.jpg wiki-commons:Special:FilePath/TSETdiagc.jpg wiki-commons:Special:FilePath/TSETmunc.jpg wiki-commons:Special:FilePath/VesiclesPlantsc.jpg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Vesicular_transport_adaptor_protein |
| is dbo:wikiPageDisambiguates of |
dbr:Adaptor_protein |
| is dbo:wikiPageRedirects of |
dbr:Adaptor_proteins,_vesicular_transport dbr:Vesicular_transport_adaptor_proteins dbr:Adaptor_disease |
| is dbo:wikiPageWikiLink of |
dbr:Endoplasmic_reticulum dbr:Intracellular_transport dbr:Sec61_alpha_1 dbr:Adaptor_complexes_medium_subunit_domain dbr:Fam89A dbr:APPL1 dbr:Adaptor_protein dbr:Adaptor_proteins,_vesicular_transport dbr:Clathrin_adaptor_protein dbr:Immunoevasin dbr:Muniscins dbr:Vesicular_transport_adaptor_proteins dbr:Adaptor_disease |
| is foaf:primaryTopic of |
wikipedia-en:Vesicular_transport_adaptor_protein |
