Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Δ9-tetrahydrocannabinol (original) (raw)
Acri JB, Morse DE, Popke EJ, Grunberg NE (1994) Nicotine increases sensory gating measured as inhibition of the acoustic startle reflex in rats. Psychopharmacology (Berl) 114:369–374 ArticleCAS Google Scholar
Albrechet-Souza L, Oliveira AR, De Luca MC, Tomazini FM, Santos NR, Brandao ML (2005) A comparative study with two types of elevated plus-maze (transparent vs. opaque walls) on the anxiolytic effects of midazolam, one-trial tolerance and fear-induced analgesia. Prog Neuropsychopharmacol Biol Psychiatry 29:571–579 ArticlePubMedCAS Google Scholar
Arnold JC, Topple AN, Hunt GE, McGregor IS (1998) Effects of pre-exposure and co-administration of the cannabinoid receptor agonist CP 55,940 on behavioral sensitization to cocaine. Eur J Pharmacol 354:9–16 ArticlePubMedCAS Google Scholar
Arnold JC, Topple AN, Mallet PE, Hunt GE, McGregor IS (2001) The distribution of cannabinoid-induced Fos expression in rat brain: differences between the Lewis and Wistar strain. Brain Res 921:240–255 ArticlePubMedCAS Google Scholar
Arseneault L, Cannon M, Witton J, Murray RM (2004) Causal association between cannabis and psychosis: examination of the evidence. Br J Psychiatry 184:110–117 ArticlePubMed Google Scholar
Balerio GN, Aso E, Maldonado R (2006) Role of the cannabinoid system in the effects induced by nicotine on anxiety-like behaviour in mice. Psychopharmacology (Berl) 184:504–513 ArticleCAS Google Scholar
Bayer TA, Falkai P, Maier W (1999) Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the “two hit hypothesis”. J Psychiatr Res 33:543–548 ArticlePubMedCAS Google Scholar
Bertoglio LJ, Carobrez AP (2002) Anxiolytic effects of ethanol and phenobarbital are abolished in test-experienced rats submitted to the elevated plus maze. Pharmacol Biochem Behav 73:963–969 ArticlePubMedCAS Google Scholar
Boissier JR, Simon P, Lwoff JM (1964) Use of a particular mouse reaction (hole board method) for the study of psychotropic drugs. Therapie 19:571–583 PubMedCAS Google Scholar
Boksa P (2004) Animal models of obstetric complications in relation to schizophrenia. Brain Res Brain Res Rev 45:1–17 ArticlePubMed Google Scholar
Bortolato M, Aru GN, Frau R, Orru M, Luckey GC, Boi G, Gessa GL (2005) The CB receptor agonist WIN 55,212-2 fails to elicit disruption of prepulse inhibition of the startle in Sprague–Dawley rats. Psychopharmacology (Berl) 177:264–271 ArticleCAS Google Scholar
Bortolato M, Campolongo P, Mangieri RA, Scattoni ML, Frau R, Trezza V, La Rana G, Russo R, Calignano A, Gessa GL, Cuomo V, Piomelli D (2006) Anxiolytic-like properties of the anandamide transport inhibitor AM404. Neuropsychopharmacology 31(12):2652–2659 ArticlePubMedCAS Google Scholar
Bouwknecht JA, van der Gugten J, Groenink L, Olivier B, Paylor RE (2004) Effects of repeated testing in two inbred strains on flesinoxan dose–response curves in three mouse models for anxiety. Eur J Pharmacol 494:35–44 ArticlePubMedCAS Google Scholar
Braga RJ, Mendlowicz MV, Marrocos RP, Figueira IL (2005) Anxiety disorders in outpatients with schizophrenia: prevalence and impact on the subjective quality of life. J Psychiatr Res 39:409–414 ArticlePubMed Google Scholar
Cardno AG, Gottesman II (2000) Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics. Am J Med Genet 97:12–17 ArticlePubMedCAS Google Scholar
Compton DR, Aceto MD, Lowe J, Martin BR (1996) In vivo characterization of a specific cannabinoid receptor antagonist (SR141716A): inhibition of delta 9-tetrahydrocannabinol-induced responses and apparent agonist activity. J Pharmacol Exp Ther 277:586–594 PubMedCAS Google Scholar
Costall B, Jones BJ, Kelly ME, Naylor RJ, Tomkins DM (1989) Exploration of mice in a black and white test box: validation as a model of anxiety. Pharmacol Biochem Behav 32:777–785 ArticlePubMedCAS Google Scholar
Coyle JT (1996) The glutamatergic dysfunction hypothesis for schizophrenia. Harv Rev Psychiatry 3:241–253 PubMedCAS Google Scholar
Crawley JN (1985) Exploratory behavior models of anxiety in mice. Neurosci Biobehav Rev 9:37–44 ArticlePubMedCAS Google Scholar
Crawley JN (1999) Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests. Brain Res 835:18–26 ArticlePubMedCAS Google Scholar
Cruz-Morales SE, Santos NR, Brandao ML (2002) One-trial tolerance to midazolam is due to enhancement of fear and reduction of anxiolytic-sensitive behaviors in the elevated plus-maze retest in the rat. Pharmacol Biochem Behav 72:973–978 ArticlePubMedCAS Google Scholar
DeFries JC, Hegmann JP, Weir MW (1966) Open-field behavior in mice: evidence for a major gene effect mediated by the visual system. Science 154:1577–1579 ArticlePubMedCAS Google Scholar
Degenhardt L, Hall W (2002) Cannabis and psychosis. Curr Psychiatry Rep 4:191–196 PubMed Google Scholar
Degenhardt L, Hall W, Lynskey M (2001) Alcohol, cannabis and tobacco use among Australians: a comparison of their associations with other drug use and use disorders, affective and anxiety disorders, and psychosis. Addiction 96:1603–1614 ArticlePubMedCAS Google Scholar
Degenhardt L, Hall W, Lynskey M (2003) Testing hypotheses about the relationship between cannabis use and psychosis. Drug Alcohol Depend 71:37–48 ArticlePubMed Google Scholar
Denenberg VH (1969) Open-field behavior in the rat: what does it mean? Ann N Y Acad Sci 159:852–859 ArticlePubMedCAS Google Scholar
Dixon AK, Huber C, Lowe DA (1994) Clozapine promotes approach-oriented behavior in male mice. J Clin Psychiatry 55:4–7 PubMed Google Scholar
Duan J, Martinez M, Sanders AR, Hou C, Krasner AJ, Schwartz DB, Gejman PV (2005) Neuregulin 1 (NRG1) and schizophrenia: analysis of a US family sample and the evidence in the balance. Psychol Med 35:1599–1610 ArticlePubMed Google Scholar
Duncan GE, Sheitman BB, Lieberman JA (1999) An integrated view of pathophysiological models of schizophrenia. Brain Res Brain Res Rev 29:250–264 ArticlePubMedCAS Google Scholar
Ellenbroek BA, Cools AR (2000) Animal models for the negative symptoms of schizophrenia. Behav Pharmacol 11:223–233 PubMedCAS Google Scholar
Espejo EF (1997) Effects of weekly or daily exposure to the elevated plus-maze in male mice. Behav Brain Res 87:233–238 ArticlePubMedCAS Google Scholar
Falls DL (2003) Neuregulins: functions, forms, and signaling strategies. Exp Cell Res 284:14–30 ArticlePubMedCAS Google Scholar
Farber NB, Wozniak DF, Price MT, Labruyere J, Huss J, St Peter H, Olney JW (1995) Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia? Biol Psychiatry 38:788–796 ArticlePubMedCAS Google Scholar
Favrat B, Menetrey A, Augsburger M, Rothuizen LE, Appenzeller M, Buclin T, Pin M, Mangin P, Giroud C (2005) Two cases of “cannabis acute psychosis” following the administration of oral cannabis. BMC Psychiatry 5:17 ArticlePubMed Google Scholar
Fernandez-Espejo E, Galan-Rodriguez B (2004) Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor. Psychopharmacology (Berl) 175:220–224 CAS Google Scholar
File SE (1988) How good is social interaction as a test of anxiety? In: Simon P, Soubrié P, Wildlocher D (eds) Animal models of psychiatric disorders. Selected models of anxiety, depression and psychosis. Karger, Basel, München, Paris, London, New York, New Delhi, Singapore, Tokyo, and Sydney, pp 151–166 Google Scholar
File SE (1990) One-trial tolerance to the anxiolytic effects of chlordiazepoxide in the plus-maze. Psychopharmacology (Berl) 100:281–282 ArticleCAS Google Scholar
File SE, Mabbutt PS, Hitchcott PK (1990) Characterisation of the phenomenon of “one-trial tolerance” to the anxiolytic effect of chlordiazepoxide in the elevated plus-maze. Psychopharmacology (Berl) 102:98–101 ArticleCAS Google Scholar
Geyer MA, Swerdlow NR (1998) Measurement of startle response, prepulse inhibition, and habituation. In: Crawley JN, Skolnick P (eds) Current protocols in neuroscience, New York, pp 8.7.1–8.7.15
Geyer MA, Krebs-Thomson K, Braff DL, Swerdlow NR (2001) Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) 156:117–154 ArticleCAS Google Scholar
Graham FK (1975) Presidential Address, 1974. The more or less startling effects of weak prestimulation. Psychophysiology 12:238–248 ArticlePubMedCAS Google Scholar
Grech A, Van Os J, Jones PB, Lewis SW, Murray RM (2005) Cannabis use and outcome of recent onset psychosis. Eur Psychiatr 20:349–353 Article Google Scholar
Hall W, Degenhardt L (2000) Cannabis use and psychosis: a review of clinical and epidemiological evidence. Aust N Z J Psychiatry 34:26–34 ArticlePubMedCAS Google Scholar
Hashimoto R, Straub RE, Weickert CS, Hyde TM, Kleinman JE, Weinberger DR (2004) Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia. Mol Psychiatry 9:299–307 ArticlePubMedCAS Google Scholar
Henquet C, Murray R, Linszen D, van Os J (2005) The environment and schizophrenia: the role of cannabis use. Schizophr Bull 31:608–612 ArticlePubMed Google Scholar
Hides L, Dawe S, Kavanagh DJ, Young RM (2006) Psychotic symptom and cannabis relapse in recent-onset psychosis. Prospective study. Br J Psychiatry 189:137–143 ArticlePubMedCAS Google Scholar
Hoffman HS, Searle JL (1968) Acoustic and temporal factors in the evocation of startle. J Acoust Soc Am 43:269–282 ArticlePubMedCAS Google Scholar
Hogg S (1996) A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacol Biochem Behav 54:21–30 ArticlePubMedCAS Google Scholar
Holmes A, Rodgers RJ (1999) Influence of spatial and temporal manipulations on the anxiolytic efficacy of chlordiazepoxide in mice previously exposed to the elevated plus-maze. Neurosci Biobehav Rev 23:971–980 ArticlePubMedCAS Google Scholar
Iwata N, Suzuki T, Ikeda M, Kitajima T, Yamanouchi Y, Inada T, Ozaki N (2004) No association with the neuregulin 1 haplotype to Japanese schizophrenia. Mol Psychiatry 9:126–127 ArticlePubMedCAS Google Scholar
Karl T, Pabst R, von Horsten S (2003) Behavioral phenotyping of mice in pharmacological and toxicological research. Exp Toxicol Pathol 55:69–83 ArticlePubMed Google Scholar
Karl T, Duffy L, Scimone A, Harvey RP, Schofield P (2006) Altered motor activity, exploration, and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia. Genes Brain Behav (in press)
Kask A, Nguyen HP, Pabst R, von Horsten S (2001) Factors influencing behavior of group-housed male rats in the social interaction test: focus on cohort removal. Physiol Behav 74:277–282 ArticlePubMedCAS Google Scholar
Kumari V, Soni W, Sharma T (2001) Influence of cigarette smoking on prepulse inhibition of the acoustic startle response in schizophrenia. Hum Psychopharmacol 16:321–326 ArticlePubMed Google Scholar
Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, Harrison PJ, Kleinman JE, Weinberger DR (2006) Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease. Proc Natl Acad Sci USA 103:6747–6752 ArticlePubMedCAS Google Scholar
Lee C, Rodgers RJ (1990) Antinociceptive effects of elevated plus-maze exposure: influence of opiate receptor manipulations. Psychopharmacology (Berl) 102:507–513 ArticleCAS Google Scholar
Leng A, Yee BK, Feldon J, Ferger B (2004) Acoustic startle response, prepulse inhibition, and spontaneous locomotor activity in MPTP-treated mice. Behav Brain Res 154:449–456 ArticlePubMedCAS Google Scholar
Leweke FM, Gerth CW, Klosterkotter J (2004) Cannabis-associated psychosis: current status of research. CNS Drugs 18:895–910 ArticlePubMed Google Scholar
Linszen DH, Dingemans PM, Lenior ME (1994) Cannabis abuse and the course of recent-onset schizophrenic disorders. Arch Gen Psychiatry 51:273–279 PubMedCAS Google Scholar
Malone DT, Taylor DA (2006) The effect of delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats. Behav Brain Res 166:101–109 ArticlePubMedCAS Google Scholar
Mansbach RS, Geyer MA (1989) Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat. Neuropsychopharmacology 2:299–308 ArticlePubMedCAS Google Scholar
Mansbach RS, Geyer MA, Braff DL (1988) Dopaminergic stimulation disrupts sensorimotor gating in the rat. Psychopharmacology (Berl) 94:507–514 ArticleCAS Google Scholar
Mansbach RS, Rovetti CC, Winston EN, Lowe JA 3rd (1996) Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats. Psychopharmacology (Berl) 124:315–322 ArticleCAS Google Scholar
Martin RS, Secchi RL, Sung E, Lemaire M, Bonhaus DW, Hedley LR, Lowe DA (2003) Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in the rat. Psychopharmacology (Berl) 165:128–135 CAS Google Scholar
Montgomery KC (1958) The relation between fear induced by novel stimulation and exploratory behavior. J Comp Physiol Psychol 48:254–260 Article Google Scholar
Nagai H, Egashira N, Sano K, Ogata A, Mizuki A, Mishima K, Iwasaki K, Shoyama Y, Nishimura R, Fujiwara M (2006) Antipsychotics improve delta9-tetrahydrocannabinol-induced impairment of the prepulse inhibition of the startle reflex in mice. Pharmacol Biochem Behav 84:330–336 ArticlePubMedCAS Google Scholar
Nyberg JM, Vekovischeva O, Sandnabba NK (2003) Anxiety profiles of mice selectively bred for intermale aggression. Behav Genet 33:503–511 ArticlePubMed Google Scholar
Onaivi ES, Green MR, Martin BR (1990) Pharmacological characterization of cannabinoids in the elevated plus maze. J Pharmacol Exp Ther 253:1002–1009 PubMedCAS Google Scholar
Onaivi ES, Chakrabarti A, Gwebu ET, Chaudhuri G (1995) Neurobehavioral effects of delta 9-THC and cannabinoid (CB1) receptor gene expression in mice. Behav Brain Res 72:115–125 ArticlePubMedCAS Google Scholar
O’Tuathaigh CM, O’Sullivan GJ, Kinsella A, Harvey RP, Tighe O, Croke DT, Waddington JL (2006) Sexually dimorphic changes in the exploratory and habituation profiles of heterozygous neuregulin-1 knockout mice. Neuroreport 17:79–83 ArticlePubMedCAS Google Scholar
Pellow S, Chopin P, File SE, Briley M (1985) Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 14:149–167 ArticlePubMedCAS Google Scholar
Postma P, Gray JA, Sharma T, Geyer M, Mehrotra R, Das M, Zachariah E, Hines M, Williams SC, Kumari V (2006) A behavioural and functional neuroimaging investigation into the effects of nicotine on sensorimotor gating in healthy subjects and persons with schizophrenia. Psychopharmacology (Berl) 184:589–599 ArticleCAS Google Scholar
Rodgers RJ (1997) Animal models of ‘anxiety’: where next? Behav Pharmacol 8:477–496; discussion 497–504 ArticlePubMedCAS Google Scholar
Rodgers RJ, Johnson NJ (1995) Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety. Pharmacol Biochem Behav 52:297–303 ArticlePubMedCAS Google Scholar
Rodgers RJ, Shepherd JK (1993) Influence of prior maze experience on behaviour and response to diazepam in the elevated plus-maze and light/dark tests of anxiety in mice. Psychopharmacology (Berl) 113:237–242 ArticleCAS Google Scholar
Rodgers RJ, Lee C, Shepherd JK (1992) Effects of diazepam on behavioural and antinociceptive responses to the elevated plus-maze in male mice depend upon treatment regimen and prior maze experience. Psychopharmacology (Berl) 106:102–110 ArticleCAS Google Scholar
Rodgers RJ, Johnson NJ, Cole JC, Dewar CV, Kidd GR, Kimpson PH (1996) Plus-maze retest profile in mice: importance of initial stages of trail 1 and response to post-trail cholinergic receptor blockade. Pharmacol Biochem Behav 54:41–50 ArticlePubMedCAS Google Scholar
Rodgers RJ, Evans PM, Murphy A (2005) Anxiogenic profile of AM-251, a selective cannabinoid CB1 receptor antagonist, in plus-maze-naive and plus-maze-experienced mice. Behav Pharmacol 16:405–413 ArticlePubMedCAS Google Scholar
Rutkowska M, Jamontt J, Gliniak H (2006) Effects of cannabinoids on the anxiety-like response in mice. Pharmacol Rep 58:200–206 PubMedCAS Google Scholar
Schneider M, Koch M (2002) The cannabinoid agonist WIN 55,212-2 reduces sensorimotor gating and recognition memory in rats. Behav Pharmacol 13:29–37 PubMedCAS Google Scholar
Schneier FR, Siris SG (1987) A review of psychoactive substance use and abuse in schizophrenia. Patterns of drug choice. J Nerv Ment Dis 175:641–652 ArticlePubMedCAS Google Scholar
Schofield D, Tennant C, Nash L, Degenhardt L, Cornish A, Hobbs C, Brennan G (2006) Reasons for cannabis use in psychosis. Aust N Z J Psychiatry 40:570–574 ArticlePubMed Google Scholar
Snodgrass-Belt P, Gilbert JL, Davis FC (2005) Central administration of transforming growth factor-alpha and neuregulin-1 suppress active behaviors and cause weight loss in hamsters. Brain Res 1038:171–182 ArticlePubMedCAS Google Scholar
Stanley-Cary CC, Harris C, Martin-Iverson MT (2002) Differing effects of the cannabinoid agonist, CP 55,940, in an alcohol or Tween 80 solvent, on prepulse inhibition of the acoustic startle reflex in the rat. Behav Pharmacol 13:15–28 PubMedCAS Google Scholar
Stefansson H, Sigurdsson E, Steinthorsdottir V, Bjornsdottir S, Sigmundsson T, Ghosh S, Brynjolfsson J, Gunnarsdottir S, Ivarsson O, Chou TT, Hjaltason O, Birgisdottir B, Jonsson H, Gudnadottir VG, Gudmundsdottir E, Bjornsson A, Ingvarsson B, Ingason A, Sigfusson S, Hardardottir H, Harvey RP, Lai D, Zhou M, Brunner D, Mutel V, Gonzalo A, Lemke G, Sainz J, Johannesson G, Andresson T, Gudbjartsson D, Manolescu A, Frigge ML, Gurney ME, Kong A, Gulcher JR, Petursson H, Stefansson K (2002) Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet 71:877–892 ArticlePubMed Google Scholar
Sullivan PF, Kendler KS, Neale MC (2003) Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry 60:1187–1192 ArticlePubMed Google Scholar
Susser ES, Lin SP (1992) Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944–1945. Arch Gen Psychiatry 49:983–988 PubMedCAS Google Scholar
Tang JX, Chen WY, He G, Zhou J, Gu NF, Feng GY, He L (2004) Polymorphisms within 5′ end of the neuregulin 1 gene are genetically associated with schizophrenia in the Chinese population. Mol Psychiatry 9:11–12 ArticlePubMedCAS Google Scholar
Tibbo P, Swainson J, Chue P, LeMelledo JM (2003) Prevalence and relationship to delusions and hallucinations of anxiety disorders in schizophrenia. Depress Anxiety 17:65–72 ArticlePubMed Google Scholar
Townsend MH, Wilson MS (2005) Comorbid anxiety disorders and divalproex sodium use among partial hospital patients with psychotic disorders. Compr Psychiatry 46:368–370 ArticlePubMed Google Scholar
van den Buuse M, Garner B, Gogos A, Kusljic S (2005) Importance of animal models in schizophrenia research. Aust N Z J Psychiatry 39:550–557 ArticlePubMed Google Scholar
van Gaalen MM, Steckler T (2000) Behavioural analysis of four mouse strains in an anxiety test battery. Behav Brain Res 115:95–106 ArticlePubMed Google Scholar
van Os J, Bak M, Hanssen M, Bijl RV, de Graaf R, Verdoux H (2002) Cannabis use and psychosis: a longitudinal population-based study. Am J Epidemiol 156:319–327 ArticlePubMed Google Scholar
Varvel SA, Wiley JL, Yang R, Bridgen DT, Long K, Lichtman AH, Martin BR (2006) Interactions between THC and cannabidiol in mouse models of cannabinoid activity. Psychopharmacology (Berl) 186:226–234 ArticleCAS Google Scholar
Walss-Bass C, Liu W, Lew DF, Villegas R, Montero P, Dassori A, Leach RJ, Almasy L, Escamilla M, Raventos H (2006) A novel missense mutation in the transmembrane domain of neuregulin 1 is associated with schizophrenia. Biol Psychiatry 60(6):548–553 ArticlePubMedCAS Google Scholar
Wang JH, Short J, Ledent C, Lawrence AJ, van den Buuse M (2003) Reduced startle habituation and prepulse inhibition in mice lacking the adenosine A2A receptor. Behav Brain Res 143:201–207 ArticlePubMedCAS Google Scholar
Wong AH, Van Tol HH (2003) Schizophrenia: from phenomenology to neurobiology. Neurosci Biobehav Rev 27:269–306 ArticlePubMed Google Scholar
Wright IK, Upton N, Marsden CA (1991) Resocialisation of isolation-reared rats does not alter their anxiogenic profile on the elevated X-maze model of anxiety. Physiol Behav 50:1129–1132 ArticlePubMedCAS Google Scholar
Yang JZ, Si TM, Ruan Y, Ling YS, Han YH, Wang XL, Zhou M, Zhang HY, Kong QM, Liu C, Zhang DR, Yu YQ, Liu SZ, Ju GZ, Shu L, Ma DL, Zhang D (2003) Association study of neuregulin 1 gene with schizophrenia. Mol Psychiatry 8:706–709 ArticlePubMedCAS Google Scholar