miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator (original) (raw)
Bartel, D. P. MicroRNAs: target recognition and regulatory functions. Cell136, 215–233 (2009). ArticleCAS Google Scholar
Baltimore, D., Boldin, M. P., O'Connell, R. M., Rao, D. S. & Taganov, K. D. MicroRNAs: new regulators of immune cell development and function. Nat. Immunol.9, 839–845 (2008). ArticleCAS Google Scholar
Lodish, H. F., Zhou, B., Liu, G. & Chen, C. Z. Micromanagement of the immune system by microRNAs. Nat. Rev. Immunol.8, 120–130 (2008). ArticleCAS Google Scholar
Wang, H. W. et al. Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nat. Genet.36, 687–693 (2004). ArticleCAS Google Scholar
Akira, S., Uematsu, S. & Takeuchi, O. Pathogen recognition and innate immunity. Cell124, 783–801 (2006). ArticleCAS Google Scholar
Liew, F. Y., Xu, D., Brint, E. K. & O'Neill, L. A. Negative regulation of toll-like receptor-mediated immune responses. Nat. Rev. Immunol.5, 446–458 (2005). ArticleCAS Google Scholar
Taganov, K. D., Boldin, M. P., Chang, K. J. & Baltimore, D. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc. Natl Acad. Sci. USA103, 12481–12486 (2006). ArticleCAS Google Scholar
Ceppi, M. et al. MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc. Natl Acad. Sci. USA106, 2735–2740 (2009). ArticleCAS Google Scholar
Boshoff, C. & Weiss, R. AIDS-related malignancies. Nat. Rev. Cancer2, 373–382 (2002). ArticleCAS Google Scholar
Pfeffer, S. et al. Identification of microRNAs of the herpesvirus family. Nat. Methods2, 269–276 (2005). ArticleCAS Google Scholar
Cai, X. et al. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc. Natl Acad. Sci. USA102, 5570–5575 (2005). ArticleCAS Google Scholar
Lagos, D. et al. Toll-like receptor 4 mediates innate immunity to Kaposi sarcoma herpesvirus. Cell Host Microbe4, 470–483 (2008). ArticleCAS Google Scholar
Cheng, H. Y. et al. microRNA modulation of circadian-clock period and entrainment. Neuron54, 813–829 (2007). ArticleCAS Google Scholar
Klein, M. E. et al. Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat. Neurosci.10, 1513–1514 (2007). ArticleCAS Google Scholar
Vo, N. et al. A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc. Natl Acad. Sci. USA102, 16426–16431 (2005). ArticleCAS Google Scholar
Wayman, G. A. et al. An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc. Natl Acad. Sci. USA105, 9093–9098 (2008). ArticleCAS Google Scholar
Wu, J. & Xie, X. Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol.7, R85 (2006). Article Google Scholar
Calin, G. A. et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl Acad. Sci. USA101, 11755–11760 (2004). ArticleCAS Google Scholar
Sarasin-Filipowicz, M., Krol, J., Markiewicz, I., Heim, M. H. & Filipowicz, W. Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat. Med.15, 31–33 (2009). ArticleCAS Google Scholar
Mayr, B. & Montminy, M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat. Rev. Mol. Cell Biol.2, 599–609 (2001). ArticleCAS Google Scholar
Xing, J., Ginty, D. D. & Greenberg, M. E. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science273, 959–963 (1996). ArticleCAS Google Scholar
Xing, J., Kornhauser, J. M., Xia, Z., Thiele, E. A. & Greenberg, M. E. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. Mol. Cell Biol.18, 1946–1955 (1998). ArticleCAS Google Scholar
Sadagopan, S. et al. Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression. J. Virol.81, 3949–3968 (2007). ArticleCAS Google Scholar
Davies, S. P., Reddy, H., Caivano, M. & Cohen, P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J.351, 95–105 (2000). ArticleCAS Google Scholar
Gonzalez, G. A. & Montminy, M. R. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell59, 675–680 (1989). ArticleCAS Google Scholar
Kertesz, M., Iovino, N., Unnerstall, U., Gaul, U. & Segal, E. The role of site accessibility in microRNA target recognition. Nat. Genet.39, 1278–1284 (2007). ArticleCAS Google Scholar
Grimson, A. et al. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell27, 91–105 (2007). ArticleCAS Google Scholar
Merika, M., Williams, A. J., Chen, G., Collins, T. & Thanos, D. Recruitment of CBP/p300 by the IFN-β enhanceosome is required for synergistic activation of transcription. Mol. Cell1, 277–287 (1998). ArticleCAS Google Scholar
Horwitz, G. A. et al. Adenovirus small e1a alters global patterns of histone modification. Science321, 1084–1085 (2008). ArticleCAS Google Scholar
Pauley, K. M. et al. Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res. Ther.10, R101 (2008). Article Google Scholar
Li, M. et al. Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor. Mol. Cell Biol.20, 8254–8263 (2000). ArticleCAS Google Scholar
Lin, R. et al. HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators. Oncogene20, 800–811 (2001). ArticleCAS Google Scholar
Goodman, R. H. & Smolik, S. CBP/p300 in cell growth, transformation, and development. Genes Dev.14, 1553–1577 (2000). CASPubMed Google Scholar
Umbach, J. L. & Cullen, B. R. The role of RNAi and microRNAs in animal virus replication and antiviral immunity. Genes Dev.23, 1151–1164 (2009). ArticleCAS Google Scholar
Iyer, N. G., Ozdag, H. & Caldas, C. p300/CBP and cancer. Oncogene23, 4225–4231 (2004). ArticleCAS Google Scholar
Marmorstein, R. & Trievel, R. C. Histone modifying enzymes: structures, mechanisms, and specificities. Biochim. Biophys. Acta1789, 58–68 (2009). ArticleCAS Google Scholar
Bourboulia, D. et al. Short- and long-term effects of highly active antiretroviral therapy on Kaposi sarcoma-associated herpesvirus immune responses and viraemia. AIDS18, 485–493 (2004). ArticleCAS Google Scholar
Fabani, M. M. & Gait, M. J. miR-122 targeting with LNA/2'-O-methyl oligonucleotide mixmers, peptide nucleic acids (PNA), and PNA-peptide conjugates. RNA14, 336–346 (2008). ArticleCAS Google Scholar
Smyth, G. K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol.3, Article 3 (2004). Article Google Scholar
Benjamini, Y., Drai, D., Elmer, G., Kafkafi, N. & Golani, I. Controlling the false discovery rate in behavior genetics research. Behav. Brain Res.125, 279–284 (2001). ArticleCAS Google Scholar