FSCN3 (original) (raw)

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Protein-coding gene in the species Homo sapiens

FSCN3
Identifiers
Aliases	FSCN3, fascin actin-bundling protein 3
External IDs	OMIM: 615800; MGI: 1890386; HomoloGene: 10475; GeneCards: FSCN3; OMA:FSCN3 - orthologs
Gene location (Human)Chr.Chromosome 7 (human)[1]Band7q32.1Start127,591,409 bp[1]End127,602,144 bp[1]
Gene location (Mouse)Chr.Chromosome 6 (mouse)[2]Band6|6 A3.3Start28,427,788 bp[2]End28,438,621 bp[2]
RNA expression patternBgeeHuman Mouse (ortholog)Top expressed inspermleft testisright testistesticlegranulocytegonadmuscle of thighcerebellar cortexcerebellar hemisphereprefrontal cortexTop expressed inseminiferous tubulespermatidblastocystembryospermatocyteembryoupper armmedial ganglionic eminencetriceps brachii muscleyolk sacMore reference expression dataBioGPSn/a
Gene ontologyMolecular function protein-macromolecule adaptor activity actin binding actin filament binding Cellular component cytoskeleton actin cytoskeleton cytoplasm filamentous actin ruffle microvillus lamellipodium filopodium growth cone cell projection membrane Biological process spermatid development actin filament organization anatomical structure morphogenesis establishment or maintenance of cell polarity actin filament bundle assembly cell migration Sources:Amigo / QuickGO
OrthologsSpeciesHuman MouseEntrez2999956223EnsemblENSG00000106328ENSMUSG00000029707UniProtQ9NQT6Q9QXW4RefSeq (mRNA)NM_020369NM_019569RefSeq (protein)NP_065102NP_062515Location (UCSC)Chr 7: 127.59 – 127.6 MbChr 6: 28.43 – 28.44 MbPubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Fascin-3 also known as testis fascin is a protein that in humans is encoded by the FSCN3 gene.[5][6]

• Fascin

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106328 – Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029707 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: fascin homolog 3".
6. ^ Tubb B, Mulholland DJ, Vogl W, Lan ZJ, Niederberger C, Cooney A, Bryan J (April 2002). "Testis fascin (FSCN3): a novel paralog of the actin-bundling protein fascin expressed specifically in the elongate spermatid head". Exp. Cell Res. 275 (1): 92–109. doi:10.1006/excr.2002.5486. PMID 11925108.

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Tubb BE, Bardien-Kruger S, Kashork CD, et al. (2000). "Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes". Genomics. 65 (2): 146–56. doi:10.1006/geno.2000.6156. PMID 10783262.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.