KIF13A (original) (raw)

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Protein-coding gene in the species Homo sapiens

KIF13A
Identifiers
Aliases	KIF13A, RBKIN, bA500C11.2, kinesin family member 13A
External IDs	OMIM: 605433; MGI: 1098264; HomoloGene: 22589; GeneCards: KIF13A; OMA:KIF13A - orthologs
Gene location (Human)Chr.Chromosome 6 (human)[1]Band6p22.3Start17,759,183 bp[1]End17,987,635 bp[1]
Gene location (Mouse)Chr.Chromosome 13 (mouse)[2]Band13|13 A5Start46,749,087 bp[2]End46,929,867 bp[2]
RNA expression patternBgeeHuman Mouse (ortholog)Top expressed intendon of biceps brachiiSkeletal muscle tissue of rectus abdominisSkeletal muscle tissue of biceps brachiisaphenous veininternal globus pallidusbody of tongueright ventriclejejunumsynovial jointnippleTop expressed inmuscle of thighsoleus muscleretinal pigment epitheliumatriummyocardium of ventricleskeletal muscle tissuegenital tubercletemporal muscledigastric muscletriceps brachii muscleMore reference expression dataBioGPSn/a
Gene ontologyMolecular function microtubule motor activity nucleotide binding microtubule binding ATPase activity protein binding ATP binding Cellular component cytoplasm endosome centrosome Golgi apparatus trans-Golgi network membrane membrane kinesin complex Golgi membrane microtubule organizing center midbody endosome membrane microtubule cytoskeleton intracellular anatomical structure Biological process plus-end-directed vesicle transport along microtubule cytoskeleton-dependent intracellular transport endosome to lysosome transport cell division melanosome organization microtubule-based movement vesicle cargo loading protein transport cell cycle intracellular protein transport Golgi to plasma membrane protein transport regulation of cytokinesis Sources:Amigo / QuickGO
OrthologsSpeciesHuman MouseEntrez6397116553EnsemblENSG00000137177ENSMUSG00000021375UniProtQ9H1H9Q9EQW7RefSeq (mRNA)NM_001105566NM_001105567NM_001105568NM_001243423NM_022113NM_010617RefSeq (protein)NP_001099036NP_001099037NP_001099038NP_001230352NP_071396NP_034747Location (UCSC)Chr 6: 17.76 – 17.99 MbChr 13: 46.75 – 46.93 MbPubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin-like protein KIF13A is a protein that in humans is encoded by the KIF13A gene.[5][6]

KIF13A has been shown to interact with AP1B1.[5]

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137177 – Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021375 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ a b Nakagawa T, Setou M, Seog D, Ogasawara K, Dohmae N, Takio K, Hirokawa N (Jan 2001). "A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex". Cell. 103 (4): 569–81. doi:10.1016/S0092-8674(00)00161-6. PMID 11106728. S2CID 18245989.
6. ^ "Entrez Gene: KIF13A kinesin family member 13A".

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• Chen D, Pajovic S, Duckett A, et al. (2002). "Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN". Cancer Res. 62 (4): 967–71. PMID 11861365.
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• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
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• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.