OR4M2 (original) (raw)

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Protein-coding gene in the species Homo sapiens

OR4M2
Identifiers
Aliases	OR4M2, OR15-3, olfactory receptor family 4 subfamily M member 2
External IDs	GeneCards: OR4M2; OMA:OR4M2 - orthologs
Gene location (Human)Chr.Chromosome 15 (human)[1]Band15q11.2Start22,070,241 bp[1]End22,083,221 bp[1]
RNA expression patternBgeeHuman Mouse (ortholog)Top expressed intesticlegonadleft testisright testishuman musculoskeletal systemskeletal musclemuscle of leggastrocnemius musclen/aMore reference expression dataBioGPSn/a
Gene ontologyMolecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
OrthologsSpeciesHuman MouseEntrez390538n/aEnsemblENSG00000274102ENSG00000288194n/aUniProtQ8NGB6n/aRefSeq (mRNA)NM_001004719n/aRefSeq (protein)NP_001004719n/aLocation (UCSC)Chr 15: 22.07 – 22.08 Mbn/aPubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 4M2 is a protein that in humans is encoded by the OR4M2 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

• Olfactory receptor

1. ^ a b c ENSG00000288194 GRCh38: Ensembl release 89: ENSG00000274102, ENSG00000288194 – Ensembl, May 2017
2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. ^ a b "Entrez Gene: OR4M2 olfactory receptor, family 4, subfamily M, member 2".

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

• OR4M2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.