OR6S1 (original) (raw)

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Protein-coding gene in the species Homo sapiens

OR6S1
Identifiers
Aliases	OR6S1, OR14-37, OR6S1Q, olfactory receptor family 6 subfamily S member 1
External IDs	MGI: 3030584; HomoloGene: 19719; GeneCards: OR6S1; OMA:OR6S1 - orthologs
Gene location (Human)Chr.Chromosome 14 (human)[1]Band14q11.2Start20,640,696 bp[1]End20,641,691 bp[1]
Gene location (Mouse)Chr.Chromosome 14 (mouse)[2]Band14|14 C1Start51,303,758 bp[2]End51,311,892 bp[2]
RNA expression patternBgeeHuman Mouse (ortholog)Top expressed inlymph nodeurinary bladderTop expressed inlungMore reference expression dataBioGPSMore reference expression data
Gene ontologyMolecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
OrthologsSpeciesHuman MouseEntrez341799404319EnsemblENSG00000181803ENSMUSG00000035932UniProtQ8NH40E9Q0Z1RefSeq (mRNA)NM_001001968NM_207558RefSeq (protein)NP_001001968NP_997441Location (UCSC)Chr 14: 20.64 – 20.64 MbChr 14: 51.3 – 51.31 MbPubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 6S1 is a protein that in humans is encoded by the OR6S1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

• Olfactory receptor

1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181803 – Ensembl, May 2017
2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035932 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ a b "Entrez Gene: OR6S1 olfactory receptor, family 6, subfamily S, member 1".

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

• OR6S1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.