Neurocognitive models of aggression, the antisocial personality disorders, and psychopathy (original) (raw)

Abstract

This paper considers neurocognitive models of aggression and relates them to explanations of the antisocial personality disorders. Two forms of aggression are distinguished: reactive aggression elicited in response to frustration/threat and goal directed, instrumental aggression. It is argued that different forms of neurocognitive model are necessary to explain the emergence of these different forms of aggression. Impairments in executive emotional systems (the somatic marker system or the social response reversal system) are related to reactive aggression shown by patients with "acquired sociopathy" due to orbitofrontal cortex lesions. Impairment in the capacity to form associations between emotional unconditioned stimuli, particularly distress cues, and conditioned stimuli (the violence inhibition mechanism model) is related to the instrumental aggression shown by persons with developmental psychopathy.

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Selected References

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  1. Anderson S. W., Bechara A., Damasio H., Tranel D., Damasio A. R. Impairment of social and moral behavior related to early damage in human prefrontal cortex. Nat Neurosci. 1999 Nov;2(11):1032–1037. doi: 10.1038/14833. [DOI] [PubMed] [Google Scholar]
  2. Anderson S. W., Bechara A., Damasio H., Tranel D., Damasio A. R. Impairment of social and moral behavior related to early damage in human prefrontal cortex. Nat Neurosci. 1999 Nov;2(11):1032–1037. doi: 10.1038/14833. [DOI] [PubMed] [Google Scholar]
  3. Aniskiewicz A. S. Autonomic components of vicarious conditioning and psychopathy. J Clin Psychol. 1979 Jan;35(1):60–67. doi: 10.1002/1097-4679(197901)35:1<60::aid-jclp2270350106>3.0.co;2-r. [DOI] [PubMed] [Google Scholar]
  4. Bechara A., Damasio H., Damasio A. R. Emotion, decision making and the orbitofrontal cortex. Cereb Cortex. 2000 Mar;10(3):295–307. doi: 10.1093/cercor/10.3.295. [DOI] [PubMed] [Google Scholar]
  5. Blair R. J. A cognitive developmental approach to mortality: investigating the psychopath. Cognition. 1995 Oct;57(1):1–29. doi: 10.1016/0010-0277(95)00676-p. [DOI] [PubMed] [Google Scholar]
  6. Blair R. J., Cipolotti L. Impaired social response reversal. A case of 'acquired sociopathy'. Brain. 2000 Jun;123(Pt 6):1122–1141. doi: 10.1093/brain/123.6.1122. [DOI] [PubMed] [Google Scholar]
  7. Blair R. J., Curran H. V. Selective impairment in the recognition of anger induced by diazepam. Psychopharmacology (Berl) 1999 Dec;147(3):335–338. doi: 10.1007/s002130051177. [DOI] [PubMed] [Google Scholar]
  8. Blair R. J., Jones L., Clark F., Smith M. The psychopathic individual: a lack of responsiveness to distress cues? Psychophysiology. 1997 Mar;34(2):192–198. doi: 10.1111/j.1469-8986.1997.tb02131.x. [DOI] [PubMed] [Google Scholar]
  9. Blair R. J., Jones L., Clark F., Smith M. The psychopathic individual: a lack of responsiveness to distress cues? Psychophysiology. 1997 Mar;34(2):192–198. doi: 10.1111/j.1469-8986.1997.tb02131.x. [DOI] [PubMed] [Google Scholar]
  10. Blair R. J., Morris J. S., Frith C. D., Perrett D. I., Dolan R. J. Dissociable neural responses to facial expressions of sadness and anger. Brain. 1999 May;122(Pt 5):883–893. doi: 10.1093/brain/122.5.883. [DOI] [PubMed] [Google Scholar]
  11. Bond A. J., Curran H. V., Bruce M. S., O'Sullivan G., Shine P. Behavioural aggression in panic disorder after 8 weeks' treatment with alprazolam. J Affect Disord. 1995 Dec 13;35(3):117–123. doi: 10.1016/0165-0327(95)00053-4. [DOI] [PubMed] [Google Scholar]
  12. Borrill J. A., Rosen B. K., Summerfield A. B. The influence of alcohol on judgement of facial expression of emotion. Br J Med Psychol. 1987 Mar;60(Pt 1):71–77. [PubMed] [Google Scholar]
  13. Cornell D. G., Warren J., Hawk G., Stafford E., Oram G., Pine D. Psychopathy in instrumental and reactive violent offenders. J Consult Clin Psychol. 1996 Aug;64(4):783–790. doi: 10.1037//0022-006x.64.4.783. [DOI] [PubMed] [Google Scholar]
  14. Cornell D. G., Warren J., Hawk G., Stafford E., Oram G., Pine D. Psychopathy in instrumental and reactive violent offenders. J Consult Clin Psychol. 1996 Aug;64(4):783–790. doi: 10.1037//0022-006x.64.4.783. [DOI] [PubMed] [Google Scholar]
  15. Dias R., Robbins T. W., Roberts A. C. Dissociation in prefrontal cortex of affective and attentional shifts. Nature. 1996 Mar 7;380(6569):69–72. doi: 10.1038/380069a0. [DOI] [PubMed] [Google Scholar]
  16. Frick P. J., O'Brien B. S., Wootton J. M., McBurnett K. Psychopathy and conduct problems in children. J Abnorm Psychol. 1994 Nov;103(4):700–707. doi: 10.1037//0021-843x.103.4.700. [DOI] [PubMed] [Google Scholar]
  17. Grafman J., Schwab K., Warden D., Pridgen A., Brown H. R., Salazar A. M. Frontal lobe injuries, violence, and aggression: a report of the Vietnam Head Injury Study. Neurology. 1996 May;46(5):1231–1238. doi: 10.1212/wnl.46.5.1231. [DOI] [PubMed] [Google Scholar]
  18. Hare R. D., Hart S. D., Harpur T. J. Psychopathy and the DSM-IV criteria for antisocial personality disorder. J Abnorm Psychol. 1991 Aug;100(3):391–398. doi: 10.1037//0021-843x.100.3.391. [DOI] [PubMed] [Google Scholar]
  19. Harpur T. J., Hare R. D. Assessment of psychopathy as a function of age. J Abnorm Psychol. 1994 Nov;103(4):604–609. doi: 10.1037//0021-843x.103.4.604. [DOI] [PubMed] [Google Scholar]
  20. Krakowski M., Czobor P., Carpenter M. D., Libiger J., Kunz M., Papezova H., Parker B. B., Schmader L., Abad T. Community violence and inpatient assaults: neurobiological deficits. J Neuropsychiatry Clin Neurosci. 1997 Fall;9(4):549–555. doi: 10.1176/jnp.9.4.549. [DOI] [PubMed] [Google Scholar]
  21. Lapierre D., Braun C. M., Hodgins S. Ventral frontal deficits in psychopathy: neuropsychological test findings. Neuropsychologia. 1995 Feb;33(2):139–151. doi: 10.1016/0028-3932(94)00110-b. [DOI] [PubMed] [Google Scholar]
  22. Moffitt T. E. Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev. 1993 Oct;100(4):674–701. [PubMed] [Google Scholar]
  23. Morgan A. B., Lilienfeld S. O. A meta-analytic review of the relation between antisocial behavior and neuropsychological measures of executive function. Clin Psychol Rev. 2000 Jan;20(1):113–136. doi: 10.1016/s0272-7358(98)00096-8. [DOI] [PubMed] [Google Scholar]
  24. Patrick C. J., Bradley M. M., Lang P. J. Emotion in the criminal psychopath: startle reflex modulation. J Abnorm Psychol. 1993 Feb;102(1):82–92. doi: 10.1037//0021-843x.102.1.82. [DOI] [PubMed] [Google Scholar]
  25. Patrick C. J., Cuthbert B. N., Lang P. J. Emotion in the criminal psychopath: fear image processing. J Abnorm Psychol. 1994 Aug;103(3):523–534. doi: 10.1037//0021-843x.103.3.523. [DOI] [PubMed] [Google Scholar]
  26. Patrick C. J. Emotion and psychopathy: startling new insights. Psychophysiology. 1994 Jul;31(4):319–330. doi: 10.1111/j.1469-8986.1994.tb02440.x. [DOI] [PubMed] [Google Scholar]
  27. Rolls E. T. The orbitofrontal cortex. Philos Trans R Soc Lond B Biol Sci. 1996 Oct 29;351(1346):1433–1444. doi: 10.1098/rstb.1996.0128. [DOI] [PubMed] [Google Scholar]
  28. Schmitt W. A., Brinkley C. A., Newman J. P. Testing Damasio's somatic marker hypothesis with psychopathic individuals: risk takers or risk averse? J Abnorm Psychol. 1999 Aug;108(3):538–543. doi: 10.1037//0021-843x.108.3.538. [DOI] [PubMed] [Google Scholar]
  29. Shiffman S., Hufford M., Hickcox M., Paty J. A., Gnys M., Kassel J. D. Remember that? A comparison of real-time versus retrospective recall of smoking lapses. J Consult Clin Psychol. 1997 Apr;65(2):292–300. doi: 10.1037/0022-006x.65.2.292.a. [DOI] [PubMed] [Google Scholar]
  30. Siegel A., Roeling T. A., Gregg T. R., Kruk M. R. Neuropharmacology of brain-stimulation-evoked aggression. Neurosci Biobehav Rev. 1999;23(3):359–389. doi: 10.1016/s0149-7634(98)00040-2. [DOI] [PubMed] [Google Scholar]