Plasmacytoid T cells. Immunohistochemical evidence for their monocyte/macrophage origin. (original) (raw)

Am J Pathol. 1988 Oct; 133(1): 15–21.

Department of Pathology, Catholic University of Leuven, Belgium.

Abstract

To elucidate the lineage of plasmacytoid T cells, their immunophenotype was studied in reactive lymph nodes with a broad panel of monoclonal antibodies. Plasmacytoid T cells expressed several myelomonocytic markers, and almost all markers highly selective for macrophages. They lacked granulocyte-associated and B or T lymphocyte-associated antigens. These results provide strong evidence that plasmacytoid T cells are of monocyte lineage.

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