tern.mmrm: Tables and Graphs for Mixed Models for Repeated Measures (MMRM) (original) (raw)

Mixed models for repeated measures (MMRM) are a popular choice for analyzing longitudinal continuous outcomes in randomized clinical trials and beyond; see for example Cnaan, Laird and Slasor (1997) <doi:10.1002/(SICI)1097-0258(19971030)16:20%3C2349::AID-SIM667%3E3.0.CO;2-E>. This package provides an interface for fitting MMRM within the 'tern' <https://cran.r-project.org/package=tern> framework by Zhu et al. (2023) and tabulate results easily using 'rtables' <https://cran.r-project.org/package=rtables> by Becker et al. (2023). It builds on 'mmrm' <https://cran.r-project.org/package=mmrm> by Sabanés Bové et al. (2023) for the actual MMRM computations.

Version:	0.3.3
Depends:	R (≥ 3.6), tern (≥ 0.9.9)
Imports:	checkmate (≥ 2.1.0), cowplot, dplyr (≥ 1.1.0), emmeans (≥ 1.10.4), formatters (≥ 0.5.11), generics, ggplot2, lifecycle (≥ 0.2.0), magrittr, mmrm (≥ 0.3.5), parallelly (≥ 1.25.0), rlang (≥ 1.0.1), rtables (≥ 0.6.13), stats, tidyr (≥ 0.8.3)
Suggests:	broom (≥ 0.7.10), grid, knitr (≥ 1.42), maditr (≥ 0.8.1), Matrix, rmarkdown (≥ 2.23), testthat (≥ 3.1), TMB, vdiffr (≥ 1.0.7), withr (≥ 2.0.0)
Published:	2025-07-04
DOI:	10.32614/CRAN.package.tern.mmrm
Author:	Daniel Sabanés Bové [aut], Joe Zhu [aut, cre], Godwin Yung [aut], Francois Collin [aut], Julia Dedic [aut], Jana Stoilova [aut], F. Hoffmann-La Roche AG [cph, fnd]
Maintainer:	Joe Zhu <joe.zhu at roche.com>
BugReports:	https://github.com/insightsengineering/tern.mmrm/issues
License:	Apache License 2.0
URL:	https://github.com/insightsengineering/tern.mmrm,https://insightsengineering.github.io/tern.mmrm/
NeedsCompilation:	no
Language:	en-US
Materials:	NEWS
CRAN checks:	tern.mmrm results

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