| Favorite Pop/Rock Male ArtistJustin Bieber |
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other nominees:EminemUsher |
| Favorite Pop/Rock Female ArtistLady Gaga |
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other nominees:KeshaKaty Perry |
| Favorite Pop/Rock Band/Duo/GroupBlack Eyed Peas |
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other nominees:Lady AntebellumTrain |
| Favorite Pop/Rock AlbumJustin Bieber My World 2.0 |
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other nominees:Eminem - RecoveryKaty Perry - Teenage Dream |
| Favorite Soundtrack Glee: The Music, Volume 3 Showstoppers |
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other nominees:Iron Man 2The Twilight Saga: Eclipse |
| Favorite Soul/R&B Male ArtistUsher |
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other nominees:Chris Brown Trey Songz |
| Favorite Soul/R&B Female ArtistRihanna |
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other nominees:Alicia KeysSade |
| Favorite Soul/R&B AlbumUsher Raymond V. Raymond |
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other nominees:Alicia Keys - The Element Of FreedomSade - Soldier Of Love |
| Favorite Country Male Artist Brad Paisley |
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other nominees:Jason AldeanLuke Bryan |
| Favorite Country Female ArtistTaylor Swift |
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other nominees:Miranda LambertCarrie Underwood |
| Favorite Country Band/Duo/GroupLady Antebellum |
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other nominees: Zac Brown Band Rascal Flatts |
| Favorite Country AlbumCarrie Underwood Play On |
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other nominees:Jason Aldean - Wide OpenLady Antebellum - Need You Now |
| Favorite Rap/Hip-Hop Male ArtistEminem |
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other nominees:B.o.BDrake |
| Favorite Rap/Hip-Hop AlbumEminem Recovery |
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other nominees:B.o.B - B.o.B Presents: The Adventures Of Bobby RayDrake - Thank Me Later |
| Favorite Adult Contemporary ArtistMichael Buble |
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other nominees:Lady AntebellumTrain |
| Favorite Alternative Artist Muse |
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other nominees: PhoenixVampire Weekend |
| Favorite Contemporary Inspirational Artist MercyMe |
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other nominees: Casting Crowns TobyMac |
| Favorite Latin ArtistShakira |
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other nominees: Daddy YankeeEnrique Iglesias |
| Breakthrough ArtistJustin Bieber |
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other nominees:B.o.BTaio CruzJason DeruloKeshaLady Antebellum Travie McCoy Mike Posner |