The Clinical Proteomic Technologies for Cancer (original) (raw)

Four And A Half LIM Domains 1 Peptide 1

Background

Catalog Number:

CPTC-FHL1-1

RRID:

AB_2884019

Target Antigen:

Four And A Half LIM Domains 1 Peptide 1

Isotype:

IgG

Species:

Rabbit Recombinant Cloned Antibody

Last Updated:

08/23/2022

Antigen Recognition(s):

Peptide

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Characterization Data [Compare Characterization Data]
Background

NCI Identification Number:

00329

Antigen Name:

Four And A Half LIM Domains 1 Peptide 1

CPTC Name:

CPTC-FHL1 Peptide 1

Aliases:

Four And A Half LIM Domains 1; SLIM1; Four And A Half LIM Domains Protein 1; Skeletal Muscle LIM-Protein 1; LIM Protein SLIMMER; SLIM-1; FHL-1; FHL1B; FLH1A; XMPMA; SLIM; Four-And-A-Half Lin11, Isl-1 And Mec-3 Domains 1; Four-And-A-Half LIM Domains 1; BA535K18.1; MGC111107; SLIMMER; RBMX1A; RBMX1B; FCMSU; FHL1A; KYO-T; KYOT; FHL1

Function:

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.FHL1 (Four And A Half LIM Domains 1) is a Protein Coding gene. Diseases associated with FHL1 include Myopathy, X-Linked, With Postural Muscle Atrophy and Scapuloperoneal Myopathy, X-Linked Dominant. Among its related pathways are Notch Signaling Pathway (WikiPathways) and JAK-STAT signaling pathway. Gene Ontology (GO) annotations related to this gene include ion channel binding. An important paralog of this gene is ZFHX4.May have an involvement in muscle development or hypertrophy.

Chromosomal Localization:

Xq26.3

Accession Number:

NP_001153174.1

UniProt Accession Number:

Q13642

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

AIVAGDQNVEYK

Native Sequence:

Calculated Isoelectric Point:

Molecular Weight:

1320

Last Updated:

08/23/2020

Characterization Data

SOPs

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