Emre Erturk - Academia.edu (original) (raw)
Papers by Emre Erturk
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2010
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2009
A 72-year-old male patient presented with a complaint of pain in both legs during short walks of ... more A 72-year-old male patient presented with a complaint of pain in both legs during short walks of less than 50 meters. Physical examination showed weak arterial pulses in both lower extremities. Electrocardiographic and telecardiographic evaluations were normal. A previous abdominal ultrasonography examination performed for abdominal pain showed an abdominal aortic aneurysm. Coronary angiography findings were normal; however, peripheral angiography showed an abdominal aortic aneurysm and extensive critical bilateral peripheral artery disease. Transthoracic echocardiography disclosed an aneurysmal structure neighboring the right atrium. Transesophageal echocardiography demonstrated a 30x18-mm chamber suggestive of a right atrial appendage aneurysm. Cardiac magnetic resonance imaging confirmed the presence of the right atrial appendage aneurysm, 25x15 mm in size, over the tricuspid valve. The neck of the aneurysm was 11 mm. The patient underwent surgery which included grafting of the a...
![Research paper thumbnail of [Compensatory hemodynamic variations for cardiovascular stabilization in complete atrioventricular block before and after pacemaker implantation]](https://attachments.academia-assets.com/90344709/thumbnails/1.jpg)
](Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2009
Stabilization of the cardiovascular system is maintained by variations in hemodynamic and hormona... more Stabilization of the cardiovascular system is maintained by variations in hemodynamic and hormonal parameters in complete atrioventricular (AV) block. We investigated the variations in hemodynamic parameters and brain natriuretic peptide (BNP) levels before and after permanent pacemaker implantation for complete AV block. We evaluated 25 patients (14 men, 11 women; mean age 72+/-10 years; range 39 to 83 years) who presented with a complaint of syncope due to complete AV block. All the patients were hemodynamically stable on presentation and were monitored in the coronary care unit until permanent pacemaker implantation. Variations in the cardiovascular system were determined before and two weeks after pacemaker implantation, including mean arterial pressure (MAP), stroke volume (SV), cardiac output (CO), systemic vascular resistance (SVR), systemic aortic compliance (SAC), and BNP levels. The mean heart rates were 36+/-6 beat/min and 65+/-10 beat/min before and after pacing, respect...
Cumhuriyet Medical Journal, 2013
Özet Amaç. Endotelyal progenitör hücreler mekanik olarak endotel hücrelerinin hasarlanarak uzakla... more Özet Amaç. Endotelyal progenitör hücreler mekanik olarak endotel hücrelerinin hasarlanarak uzaklaştırılması ile ya da sitokinlerin uyarımı ile kemik iliğinden periferik kana göç ederek hasar bölgesindeki endotel hücrelerinin yerine geçerek ilgili alanı onarmaktadırlar. Daha önce bu hücrelerin stabil koroner arter hastalarında kronik süreçte azaldığı, akut koroner sendrom hastalarında ise sayıca arttığı gösterilmişti. Bu çalışmanın amacı akut koroner sendrom tanısı ile koroner yoğun bakım ünitesine yatırılan hastalarda hastalığın alt grupları arasında (ST elevasyonlu miyokard infarktüsü, ST elevasyonlu olmayan miyokard infarktüsü ve anstabil angina pektoris) endotelyal progenitor hücre sayıları bakımından fark olup olmadığının incelenmesidir. Yöntem. Çalışma verileri iki aşamada analiz edildi. İlk aşamada akut koroner sendrom sınıflamasında yer alan üç alt grup (n=112) arasında endotelyal progenitor hücre sayıları arasında fark olup olmadığı araştırıldı. Analizin ikinci aşamasında ise unstabil angına pektoris ön tanısı ile hospitalize edilen fakat enzim yüksekliği olmayan, koroner anjiografi ve ekokardiyografileri normal olarak saptanan 13 hasta daha değerlendirmeye alındı. Hastalar, enzim yüksekliği saptanmayan yani kardiyak hasarın olmadığı unstabil angına pektoris hastaları ve koroner anjiografide normal koroner arterlerin saptandığı hastalar bir grup (Grup A, n=41), kardiyak enzim yüksekliği saptanan yani kardiyak hasarın dökümente olduğu, ST elevasyonlu miyokard enfarktüsü ve ST elevasyonsuz miyokard enfarktüsü hastaları diğer bir grup (Grup B, n=84) olmak üzere iki gruba ayrıldı ve bu iki grup arasında endotelyal progenitor hücreler sayıları açısından fark olup olmadığına bakıldı. Bulgular. Çalışma bulgularımız iç grup arasında arasında endotelyal progenitor hücre sayısı açısından istatistiksel olarak anlamlı farklılık olmadığını göstermiştir (sırasıyla 3,87 ± 2,74, 5,46 ± 6,38 ve 3,95 ± 2,94, p=0,232). Yapılan istatistiksel analiz sonucunda Grup A ve Grup B arasında da endotelya progenitor hücre sayıları açısından anlamlı farklılık saptanmadı (3,89 ± 2,81'e karşılık 4,80 ± 5,22; p=0,302). Sonuç. Bu bilgiler ışığında, tedavi modalitelerindeki gelişmelere rağmen halen tedavi direnci sorununun gündemde olduğu koroner arter hastalığında bu hücrelerin terapötik yaklaşımlarda kullanılması için kemik iliğinde ve periferik kandaki sayı ve fonksiyonları, hedef dokudaki etkileri ve bu hücreleri etkileyen düzenleyici faktörler konusunda daha ileri klinik çalışmalara ihtiyaç duyulmaktadır.
JACC: Cardiovascular Imaging, 2013
The aim of this prospective study was to identify the most effective and safest regimen among dif... more The aim of this prospective study was to identify the most effective and safest regimen among different thrombolytic treatment strategies. B A C K G R O U N D The best treatment strategies for prosthetic valve thrombosis have been controversial. M E T H O D S Transesophageal echocardiography-guided thrombolytic treatment was administered to 182 consecutive patients with prosthetic valve thrombosis in 220 different episodes (156 women; mean age, 43.2 Ϯ 13.06 years) between 1993 and 2009 at a single center. These regimens chronologically included rapid (Group I), slow (Group II) streptokinase, high-dose (100 mg) tissue plasminogen activator (t-PA) (Group III), a half-dose (50 mg) and slow infusion (6 h) of t-PA without bolus (Group IV), and a low dose (25 mg) and slow infusion (6 h) of t-PA without bolus (Group V). The endpoints were thrombolytic success, in-hospital mortality, and nonfatal complication rates. R E S U L T S The overall success rate in the whole series was 83.2%; it did not differ significantly among Groups I through V (68.8%, 85.4%, 75%, 81.5%, and 85.5%, respectively; p ϭ 0.46). The overall complication rate in the whole series was 18.6%. Although the overall complication rate was similar among Groups I through IV (37.5%, 24.4 %, 33.3%, and 29.6%, respectively; p Ͼ 0.05 for each comparison), it was significantly lower in Group V (10.5%, p Ͻ 0.05 for each). The combined rates of mortality and nonfatal major complications were also lower in Group V than in the other groups, with all differences significant except for comparison of Groups IV and V. By multivariate analysis, the predictors of combined mortality plus nonfatal major complications were any thrombolytic therapy regimen other than Group V (odds ratios for Groups I through IV: 8.2, 3.8, 8.1, and 4.1, respectively; p Ͻ 0.05 for each) and a history of stroke/transient ischemic attack (odds ratio: 3.5, p ϭ 0.011). In addition, there was no mortality in Group V. C O N C L U S I O N S Low-dose slow infusion of t-PA repeated as needed without a bolus provides effective and safe thrombolysis in patients with prosthetic valve thrombosis. (Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve Thrombosis; NCT01451320) (
Circulation, Oct 28, 2008
The Journal of Heart Valve Disease, Mar 1, 2014
Background and aim of the study: The evaluation of prosthetic valve thrombosis (PVT) is crucial d... more Background and aim of the study: The evaluation of prosthetic valve thrombosis (PVT) is crucial due to higher mortality and morbidity rates. The study aim was to assess the value of fibrinogen in the diagnosis of PVT, an important and a common cause of prosthetic valve failure.
American Heart Journal, 2015
Background: Low dose (25 mg), slow infusion (6 hours) of t-PA with repetition as needed has been ... more Background: Low dose (25 mg), slow infusion (6 hours) of t-PA with repetition as needed has been shown to provide effective and safer thrombolysis in patients with prosthetic valve thrombosis (PVT).
Kardiologia polska, Jan 3, 2015
In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients ... more In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients with high risk coronary anatomy (HRCA) who most likely to require CABG is crucial. TheSYNTAX score (SXscore) is an angiographic grading tool designed to determine the complexity of coronary artery disease. It appears that CABG offers significantly better outcomes in patients with SXscore ≥33 which shows a very HRCA. We sought to assess the accuracy of the GRACE score in predicting HRCA in terms of SXscore in patients with NSTE-ACS. Patients admitted to our coronary unit with a diagnosis of NSTE-ACS and undergoing coronary angiography during hospitalization were recruited to this study. Patients were categorized into two groups based on SXscore as HRCA (SXscore ≥33) and low risk coronary anatomy (LRCA, SXscore <33). Cut-off level of GRACE score for HRCA was established by receiver operator characteristic (ROC) analysis. We studied 207 consecutive patients (mean age: 59 ± 11 years, 27.5...
The American Journal of Cardiology, 2015
In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients ... more In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients with high risk coronary anatomy (HRCA) who most likely to require CABG is crucial. The SYNTAX score (SXscore) is an angiographic grading tool designed to determine the complexity of coronary artery disease. It appears that CABG offers significantly better outcomes in patients with SXscore ≥33 which shows a very HRCA. We sought to assess the accuracy of the GRACE score in predicting HRCA in terms of SXscore in patients with NSTE-ACS.
Engineering, Technology and Applied Science Research
Cloud computing and virtualization are new but indispensable components of computer engineering a... more Cloud computing and virtualization are new but indispensable components of computer engineering and information systems curricula for universities and higher education institutions. Learning about these topics is important for students preparing to work in the IT industry. In many companies, information technology operates under tight financial constraints. Virtualization, (for example storage, desktop, and server virtualization), reduces overall IT costs through the consolidation of systems. It also results in reduced loads and energy savings in terms of the power and cooling infrastructure. Therefore it is important to investigate the practical aspects of this topic both for industry practice and for teaching purposes. This paper demonstrates some activities undertaken recently by students at the Eastern Institute of Technology New Zealand and concludes with general recommendations for IT educators, software developers, and other IT professionals.
Journal of Experimental and Clinical Medicine, 2013
Annals of Noninvasive Electrocardiology, 2014
Sudden cardiac deaths due to arrhythmias are thought to be an important cause of mortality in pat... more Sudden cardiac deaths due to arrhythmias are thought to be an important cause of mortality in patients with renal transplants. Exposure to immunosuppressive drugs may lead to QT or PR interval abnormalities which may consequently cause arrhythmias. Our study investigated the long term impact of four different immunosuppressive drugs on PR and corrected QT intervals (QTc) in renal transplant patients The study population consisted of 98 kidney transplant recipients. Study patients were receiving immunosuppressive management with tacrolimus, cyclosporine A, everolimus or azathioprine according to the local protocols. QTc and PR intervals obtained from the most recent post-transplant electrocardiograms were compared with the pre-transplant intervals dated before the transplantation procedure. Post-transplant QTc intervals had prolonged significantly in comparison to the pre-transplant QTc intervals in all groups. However, there were no significant differences between the immunosuppressive agents with regard to post-transplant QTc interval prolongation (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 0.05). There were no significant differences between the groups with regard to the pre and post-transplant PR interval changes (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 0.05). QT interval prolongation, a marker of risk for arrhythmias and sudden death, is highly prevalent among kidney transplant patients receiving different classes of immunosuppressive drugs.
Journal of Echocardiography, 2012
Journal of the American Society of Hypertension, 2014
Journal of the American College of Cardiology, 2013
Method: A total of 150 consecutive chronic MP users (50 male with a mean age of 32.5AE5.4 years),... more Method: A total of 150 consecutive chronic MP users (50 male with a mean age of 32.5AE5.4 years), cigarette smokers (50 male with a mean age of 32.1AE6.0 years) and controls (50 male with a mean age of 30.1AE5.8 years) were included in the study. Left atrial volumes were measured echocardiographically according to biplane area-length method in apical four-chamber and two-chamber views. Atrial electromechanical coupling was measured with TDI. LA mechanical function parameters were calculated. Result: LA passive emptying fraction and LA active emptying volume was significantly decreased in MP groups than control groups (p¼0.012 and, p¼0.024, respectively) and LA active emptying fraction were significantly increased in cigarette smoking groups than control groups (p¼0.003). There were the positive correlation between the amount of MP and smoking (pack years) with LA active emptying volume (r¼0.30, p¼0.002). PA lateral was significantly higher in patients with MP users than controls and PA septum was statistically higher in patients with cigarette smokers (p¼0.04 and p¼0.05, respectively). The amount of MP and smoking (pack years) was correlated with PA lateral, PA septum and interatrial electromechanical delay (r¼0.48, p<0.001, r¼0.60, p<0.001 and r¼0.66, p<0.001, respectively). Conclusıon: The main finding of this study is that some of the parameters of the atrial electromechanical coupling intervals and left atrial mechanical function were found significantly lower in MP users group and cigarette smokers group compared to healthy users whereas there was no significant difference between the MP users and cigarette smokers group. Also, the amount of MP and cigarette (pack years) was correlated with PA lateral, PA septum, interatrial electromechanical delay and LA active emptying volume.
Journal of the American College of Cardiology, 2013
International Journal of Cardiology, 2013
International Journal of Cardiology, 2009
The concurrence of acute coronary syndromes with allergic or hypersensitivity as well as with ana... more The concurrence of acute coronary syndromes with allergic or hypersensitivity as well as with anaphylactic or anaphylactoid reactions is increasingly encountered in clinical practice and there are several reports associating mast cell activation with acute cardiovascular events in adults. It was first described by Kounis as "allergic angina syndrome" progressing to "allergic myocardial infarction". The main mechanism proposed is the vasospasm of coronary arteries. This condition has not been described in childhood. We present a 13-year-old boy, admitted to our hospital with thoracic pain, 30 min after the ingestion of an oral dose of 500 mg of amoxicillin/clavulanic acid.
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2010
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2009
A 72-year-old male patient presented with a complaint of pain in both legs during short walks of ... more A 72-year-old male patient presented with a complaint of pain in both legs during short walks of less than 50 meters. Physical examination showed weak arterial pulses in both lower extremities. Electrocardiographic and telecardiographic evaluations were normal. A previous abdominal ultrasonography examination performed for abdominal pain showed an abdominal aortic aneurysm. Coronary angiography findings were normal; however, peripheral angiography showed an abdominal aortic aneurysm and extensive critical bilateral peripheral artery disease. Transthoracic echocardiography disclosed an aneurysmal structure neighboring the right atrium. Transesophageal echocardiography demonstrated a 30x18-mm chamber suggestive of a right atrial appendage aneurysm. Cardiac magnetic resonance imaging confirmed the presence of the right atrial appendage aneurysm, 25x15 mm in size, over the tricuspid valve. The neck of the aneurysm was 11 mm. The patient underwent surgery which included grafting of the a...
Türk Kardiyoloji Derneği arşivi : Türk Kardiyoloji Derneğinin yayın organıdır, 2009
Stabilization of the cardiovascular system is maintained by variations in hemodynamic and hormona... more Stabilization of the cardiovascular system is maintained by variations in hemodynamic and hormonal parameters in complete atrioventricular (AV) block. We investigated the variations in hemodynamic parameters and brain natriuretic peptide (BNP) levels before and after permanent pacemaker implantation for complete AV block. We evaluated 25 patients (14 men, 11 women; mean age 72+/-10 years; range 39 to 83 years) who presented with a complaint of syncope due to complete AV block. All the patients were hemodynamically stable on presentation and were monitored in the coronary care unit until permanent pacemaker implantation. Variations in the cardiovascular system were determined before and two weeks after pacemaker implantation, including mean arterial pressure (MAP), stroke volume (SV), cardiac output (CO), systemic vascular resistance (SVR), systemic aortic compliance (SAC), and BNP levels. The mean heart rates were 36+/-6 beat/min and 65+/-10 beat/min before and after pacing, respect...
Cumhuriyet Medical Journal, 2013
Özet Amaç. Endotelyal progenitör hücreler mekanik olarak endotel hücrelerinin hasarlanarak uzakla... more Özet Amaç. Endotelyal progenitör hücreler mekanik olarak endotel hücrelerinin hasarlanarak uzaklaştırılması ile ya da sitokinlerin uyarımı ile kemik iliğinden periferik kana göç ederek hasar bölgesindeki endotel hücrelerinin yerine geçerek ilgili alanı onarmaktadırlar. Daha önce bu hücrelerin stabil koroner arter hastalarında kronik süreçte azaldığı, akut koroner sendrom hastalarında ise sayıca arttığı gösterilmişti. Bu çalışmanın amacı akut koroner sendrom tanısı ile koroner yoğun bakım ünitesine yatırılan hastalarda hastalığın alt grupları arasında (ST elevasyonlu miyokard infarktüsü, ST elevasyonlu olmayan miyokard infarktüsü ve anstabil angina pektoris) endotelyal progenitor hücre sayıları bakımından fark olup olmadığının incelenmesidir. Yöntem. Çalışma verileri iki aşamada analiz edildi. İlk aşamada akut koroner sendrom sınıflamasında yer alan üç alt grup (n=112) arasında endotelyal progenitor hücre sayıları arasında fark olup olmadığı araştırıldı. Analizin ikinci aşamasında ise unstabil angına pektoris ön tanısı ile hospitalize edilen fakat enzim yüksekliği olmayan, koroner anjiografi ve ekokardiyografileri normal olarak saptanan 13 hasta daha değerlendirmeye alındı. Hastalar, enzim yüksekliği saptanmayan yani kardiyak hasarın olmadığı unstabil angına pektoris hastaları ve koroner anjiografide normal koroner arterlerin saptandığı hastalar bir grup (Grup A, n=41), kardiyak enzim yüksekliği saptanan yani kardiyak hasarın dökümente olduğu, ST elevasyonlu miyokard enfarktüsü ve ST elevasyonsuz miyokard enfarktüsü hastaları diğer bir grup (Grup B, n=84) olmak üzere iki gruba ayrıldı ve bu iki grup arasında endotelyal progenitor hücreler sayıları açısından fark olup olmadığına bakıldı. Bulgular. Çalışma bulgularımız iç grup arasında arasında endotelyal progenitor hücre sayısı açısından istatistiksel olarak anlamlı farklılık olmadığını göstermiştir (sırasıyla 3,87 ± 2,74, 5,46 ± 6,38 ve 3,95 ± 2,94, p=0,232). Yapılan istatistiksel analiz sonucunda Grup A ve Grup B arasında da endotelya progenitor hücre sayıları açısından anlamlı farklılık saptanmadı (3,89 ± 2,81'e karşılık 4,80 ± 5,22; p=0,302). Sonuç. Bu bilgiler ışığında, tedavi modalitelerindeki gelişmelere rağmen halen tedavi direnci sorununun gündemde olduğu koroner arter hastalığında bu hücrelerin terapötik yaklaşımlarda kullanılması için kemik iliğinde ve periferik kandaki sayı ve fonksiyonları, hedef dokudaki etkileri ve bu hücreleri etkileyen düzenleyici faktörler konusunda daha ileri klinik çalışmalara ihtiyaç duyulmaktadır.
JACC: Cardiovascular Imaging, 2013
The aim of this prospective study was to identify the most effective and safest regimen among dif... more The aim of this prospective study was to identify the most effective and safest regimen among different thrombolytic treatment strategies. B A C K G R O U N D The best treatment strategies for prosthetic valve thrombosis have been controversial. M E T H O D S Transesophageal echocardiography-guided thrombolytic treatment was administered to 182 consecutive patients with prosthetic valve thrombosis in 220 different episodes (156 women; mean age, 43.2 Ϯ 13.06 years) between 1993 and 2009 at a single center. These regimens chronologically included rapid (Group I), slow (Group II) streptokinase, high-dose (100 mg) tissue plasminogen activator (t-PA) (Group III), a half-dose (50 mg) and slow infusion (6 h) of t-PA without bolus (Group IV), and a low dose (25 mg) and slow infusion (6 h) of t-PA without bolus (Group V). The endpoints were thrombolytic success, in-hospital mortality, and nonfatal complication rates. R E S U L T S The overall success rate in the whole series was 83.2%; it did not differ significantly among Groups I through V (68.8%, 85.4%, 75%, 81.5%, and 85.5%, respectively; p ϭ 0.46). The overall complication rate in the whole series was 18.6%. Although the overall complication rate was similar among Groups I through IV (37.5%, 24.4 %, 33.3%, and 29.6%, respectively; p Ͼ 0.05 for each comparison), it was significantly lower in Group V (10.5%, p Ͻ 0.05 for each). The combined rates of mortality and nonfatal major complications were also lower in Group V than in the other groups, with all differences significant except for comparison of Groups IV and V. By multivariate analysis, the predictors of combined mortality plus nonfatal major complications were any thrombolytic therapy regimen other than Group V (odds ratios for Groups I through IV: 8.2, 3.8, 8.1, and 4.1, respectively; p Ͻ 0.05 for each) and a history of stroke/transient ischemic attack (odds ratio: 3.5, p ϭ 0.011). In addition, there was no mortality in Group V. C O N C L U S I O N S Low-dose slow infusion of t-PA repeated as needed without a bolus provides effective and safe thrombolysis in patients with prosthetic valve thrombosis. (Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve Thrombosis; NCT01451320) (
Circulation, Oct 28, 2008
The Journal of Heart Valve Disease, Mar 1, 2014
Background and aim of the study: The evaluation of prosthetic valve thrombosis (PVT) is crucial d... more Background and aim of the study: The evaluation of prosthetic valve thrombosis (PVT) is crucial due to higher mortality and morbidity rates. The study aim was to assess the value of fibrinogen in the diagnosis of PVT, an important and a common cause of prosthetic valve failure.
American Heart Journal, 2015
Background: Low dose (25 mg), slow infusion (6 hours) of t-PA with repetition as needed has been ... more Background: Low dose (25 mg), slow infusion (6 hours) of t-PA with repetition as needed has been shown to provide effective and safer thrombolysis in patients with prosthetic valve thrombosis (PVT).
Kardiologia polska, Jan 3, 2015
In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients ... more In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients with high risk coronary anatomy (HRCA) who most likely to require CABG is crucial. TheSYNTAX score (SXscore) is an angiographic grading tool designed to determine the complexity of coronary artery disease. It appears that CABG offers significantly better outcomes in patients with SXscore ≥33 which shows a very HRCA. We sought to assess the accuracy of the GRACE score in predicting HRCA in terms of SXscore in patients with NSTE-ACS. Patients admitted to our coronary unit with a diagnosis of NSTE-ACS and undergoing coronary angiography during hospitalization were recruited to this study. Patients were categorized into two groups based on SXscore as HRCA (SXscore ≥33) and low risk coronary anatomy (LRCA, SXscore <33). Cut-off level of GRACE score for HRCA was established by receiver operator characteristic (ROC) analysis. We studied 207 consecutive patients (mean age: 59 ± 11 years, 27.5...
The American Journal of Cardiology, 2015
In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients ... more In patients with non-ST elevation acute coronary syndrome (NSTE-ACS), identification of patients with high risk coronary anatomy (HRCA) who most likely to require CABG is crucial. The SYNTAX score (SXscore) is an angiographic grading tool designed to determine the complexity of coronary artery disease. It appears that CABG offers significantly better outcomes in patients with SXscore ≥33 which shows a very HRCA. We sought to assess the accuracy of the GRACE score in predicting HRCA in terms of SXscore in patients with NSTE-ACS.
Engineering, Technology and Applied Science Research
Cloud computing and virtualization are new but indispensable components of computer engineering a... more Cloud computing and virtualization are new but indispensable components of computer engineering and information systems curricula for universities and higher education institutions. Learning about these topics is important for students preparing to work in the IT industry. In many companies, information technology operates under tight financial constraints. Virtualization, (for example storage, desktop, and server virtualization), reduces overall IT costs through the consolidation of systems. It also results in reduced loads and energy savings in terms of the power and cooling infrastructure. Therefore it is important to investigate the practical aspects of this topic both for industry practice and for teaching purposes. This paper demonstrates some activities undertaken recently by students at the Eastern Institute of Technology New Zealand and concludes with general recommendations for IT educators, software developers, and other IT professionals.
Journal of Experimental and Clinical Medicine, 2013
Annals of Noninvasive Electrocardiology, 2014
Sudden cardiac deaths due to arrhythmias are thought to be an important cause of mortality in pat... more Sudden cardiac deaths due to arrhythmias are thought to be an important cause of mortality in patients with renal transplants. Exposure to immunosuppressive drugs may lead to QT or PR interval abnormalities which may consequently cause arrhythmias. Our study investigated the long term impact of four different immunosuppressive drugs on PR and corrected QT intervals (QTc) in renal transplant patients The study population consisted of 98 kidney transplant recipients. Study patients were receiving immunosuppressive management with tacrolimus, cyclosporine A, everolimus or azathioprine according to the local protocols. QTc and PR intervals obtained from the most recent post-transplant electrocardiograms were compared with the pre-transplant intervals dated before the transplantation procedure. Post-transplant QTc intervals had prolonged significantly in comparison to the pre-transplant QTc intervals in all groups. However, there were no significant differences between the immunosuppressive agents with regard to post-transplant QTc interval prolongation (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 0.05). There were no significant differences between the groups with regard to the pre and post-transplant PR interval changes (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 0.05). QT interval prolongation, a marker of risk for arrhythmias and sudden death, is highly prevalent among kidney transplant patients receiving different classes of immunosuppressive drugs.
Journal of Echocardiography, 2012
Journal of the American Society of Hypertension, 2014
Journal of the American College of Cardiology, 2013
Method: A total of 150 consecutive chronic MP users (50 male with a mean age of 32.5AE5.4 years),... more Method: A total of 150 consecutive chronic MP users (50 male with a mean age of 32.5AE5.4 years), cigarette smokers (50 male with a mean age of 32.1AE6.0 years) and controls (50 male with a mean age of 30.1AE5.8 years) were included in the study. Left atrial volumes were measured echocardiographically according to biplane area-length method in apical four-chamber and two-chamber views. Atrial electromechanical coupling was measured with TDI. LA mechanical function parameters were calculated. Result: LA passive emptying fraction and LA active emptying volume was significantly decreased in MP groups than control groups (p¼0.012 and, p¼0.024, respectively) and LA active emptying fraction were significantly increased in cigarette smoking groups than control groups (p¼0.003). There were the positive correlation between the amount of MP and smoking (pack years) with LA active emptying volume (r¼0.30, p¼0.002). PA lateral was significantly higher in patients with MP users than controls and PA septum was statistically higher in patients with cigarette smokers (p¼0.04 and p¼0.05, respectively). The amount of MP and smoking (pack years) was correlated with PA lateral, PA septum and interatrial electromechanical delay (r¼0.48, p<0.001, r¼0.60, p<0.001 and r¼0.66, p<0.001, respectively). Conclusıon: The main finding of this study is that some of the parameters of the atrial electromechanical coupling intervals and left atrial mechanical function were found significantly lower in MP users group and cigarette smokers group compared to healthy users whereas there was no significant difference between the MP users and cigarette smokers group. Also, the amount of MP and cigarette (pack years) was correlated with PA lateral, PA septum, interatrial electromechanical delay and LA active emptying volume.
Journal of the American College of Cardiology, 2013
International Journal of Cardiology, 2013
International Journal of Cardiology, 2009
The concurrence of acute coronary syndromes with allergic or hypersensitivity as well as with ana... more The concurrence of acute coronary syndromes with allergic or hypersensitivity as well as with anaphylactic or anaphylactoid reactions is increasingly encountered in clinical practice and there are several reports associating mast cell activation with acute cardiovascular events in adults. It was first described by Kounis as "allergic angina syndrome" progressing to "allergic myocardial infarction". The main mechanism proposed is the vasospasm of coronary arteries. This condition has not been described in childhood. We present a 13-year-old boy, admitted to our hospital with thoracic pain, 30 min after the ingestion of an oral dose of 500 mg of amoxicillin/clavulanic acid.