navneet kumar | CCS University, Meerut (original) (raw)
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Management Science, Jan 1, 1998
Knowledge Driven ... Amit Shankar Mukherjee * Michael A. Lapre * Luk N. Van Wassenhove 125 Summer... more Knowledge Driven ... Amit Shankar Mukherjee * Michael A. Lapre * Luk N. Van Wassenhove 125 Summer Street, Watertown, Massachusetts 02472 Boston University, School of Management, 595 Commonwealth ... In section 3, we describe our research site, our data, and its coding. ...
The EMBO Journal, Jan 1, 1986
After binding to a promoter Eschewchia coli RNA polymerase is in contact with a region of about 7... more After binding to a promoter Eschewchia coli RNA polymerase is in contact with a region of about 70 bp. Around 20 bp of this sequence are transcribed. Information encoded within this transcribed region is involved in late steps of the functional program of a promoter. By changing such 'downstream' sequences promoter strength in vivo can be varied more than 10-fold. By contrast, information for early steps of the promoter program such as recognition by the enzyme and formation of a stable complex resides in a central core region of about 35 bp. Our data show that the strength of a promoter can be limited at different levels of the overall process. Consequently promoters of identical strength can exhibit different structures due to an alternate optimization of their program.
Management Science, Jan 1, 1998
Knowledge Driven ... Amit Shankar Mukherjee * Michael A. Lapre * Luk N. Van Wassenhove 125 Summer... more Knowledge Driven ... Amit Shankar Mukherjee * Michael A. Lapre * Luk N. Van Wassenhove 125 Summer Street, Watertown, Massachusetts 02472 Boston University, School of Management, 595 Commonwealth ... In section 3, we describe our research site, our data, and its coding. ...
The EMBO Journal, Jan 1, 1986
After binding to a promoter Eschewchia coli RNA polymerase is in contact with a region of about 7... more After binding to a promoter Eschewchia coli RNA polymerase is in contact with a region of about 70 bp. Around 20 bp of this sequence are transcribed. Information encoded within this transcribed region is involved in late steps of the functional program of a promoter. By changing such 'downstream' sequences promoter strength in vivo can be varied more than 10-fold. By contrast, information for early steps of the promoter program such as recognition by the enzyme and formation of a stable complex resides in a central core region of about 35 bp. Our data show that the strength of a promoter can be limited at different levels of the overall process. Consequently promoters of identical strength can exhibit different structures due to an alternate optimization of their program.