Haragouri Mishra | Centurion University of Technology & Management (original) (raw)
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Papers by Haragouri Mishra
Journal of Pharmaceutical Research International
The rapid development of drug resistant micro-organisms is a challenge to the mankind. Nano formu... more The rapid development of drug resistant micro-organisms is a challenge to the mankind. Nano formulated compounds have proved to be effective strategy to combat bacterial drug resistance. Currently nanoparticulate systems such as nanoantibiotics are getting major attention due to their low inherent toxicity, biodegradability, bioincompatibility and tuneable mechanical characteristics. Nano formulated antibiotics are generally obtained by emulsification and gelification techniques. The effective uses of polymers in encapsulation of antibiotics show enhancement of the efficacy of antibiotics. Combined with techniques like diffraction laser spectroscopy (DLS), electron microscopy (EM) and atomic force microscopy (AFM), morphological research of nanoformulated antibiotics are conducted. The detailed study of the polymers used in the preparation of antibiotics nanoparticles as well as their impact on interactions is done by bio-analytical techniques. Antibiotics attached to nanoparticles ...
Background: The plant Gmelina arborea has been traditionally used in India for several medicinal ... more Background: The plant Gmelina arborea has been traditionally used in India for several medicinal purposes like anthelmintic, diuretic, antibacterial, hepatoprotective, anti-inflammatory, antioxidant and antidiabetic. It contains phytoconstituents like alkaloids, carbohydrates, anthraquinone glycosides, gums, mucilages, tannins, phenolic compounds and flavonoids. Aims: The objective of present study is to isolate a compound from ethanolic extract of G. arborea and to explore the anti-inflammatory activity of isolated compound. Material and methods: The isolation of compound was done by column and thin layer chromatographic methods. The isolated compound was characterized to elucidate its structure by spectroscopic methods like ultraviolet, infrared, nuclear magnetic resonance and mass spectroscopy. The anti-inflammatory activity of phytoconstituent was evaluated by Carrageenan-induced rat paw edema test method using Wistar rats as animal model. Statistical analysis used: All data are...
Journal of Pharmaceutical Research International
The rapid development of drug resistant micro-organisms is a challenge to the mankind. Nano formu... more The rapid development of drug resistant micro-organisms is a challenge to the mankind. Nano formulated compounds have proved to be effective strategy to combat bacterial drug resistance. Currently nanoparticulate systems such as nanoantibiotics are getting major attention due to their low inherent toxicity, biodegradability, bioincompatibility and tuneable mechanical characteristics. Nano formulated antibiotics are generally obtained by emulsification and gelification techniques. The effective uses of polymers in encapsulation of antibiotics show enhancement of the efficacy of antibiotics. Combined with techniques like diffraction laser spectroscopy (DLS), electron microscopy (EM) and atomic force microscopy (AFM), morphological research of nanoformulated antibiotics are conducted. The detailed study of the polymers used in the preparation of antibiotics nanoparticles as well as their impact on interactions is done by bio-analytical techniques. Antibiotics attached to nanoparticles ...
Background: The plant Gmelina arborea has been traditionally used in India for several medicinal ... more Background: The plant Gmelina arborea has been traditionally used in India for several medicinal purposes like anthelmintic, diuretic, antibacterial, hepatoprotective, anti-inflammatory, antioxidant and antidiabetic. It contains phytoconstituents like alkaloids, carbohydrates, anthraquinone glycosides, gums, mucilages, tannins, phenolic compounds and flavonoids. Aims: The objective of present study is to isolate a compound from ethanolic extract of G. arborea and to explore the anti-inflammatory activity of isolated compound. Material and methods: The isolation of compound was done by column and thin layer chromatographic methods. The isolated compound was characterized to elucidate its structure by spectroscopic methods like ultraviolet, infrared, nuclear magnetic resonance and mass spectroscopy. The anti-inflammatory activity of phytoconstituent was evaluated by Carrageenan-induced rat paw edema test method using Wistar rats as animal model. Statistical analysis used: All data are...