Immunohistochemical Study of Four Fish Tumors (original) (raw)
Journal Article
C. Iaria ,
Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, via F. Stagno d'Alcontres 31, University of Messina, 98165, Messina, Italy
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A. Ieni ,
Department of Human Pathology of Adulthood and Childhood “Gaetano Barresi”, Section of Pathology, University of Messina, Azienda Ospedaliera Universitaria Policlinico “G. Martino”, 98125, Messina, Italy
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I. Corti ,
Veterinary Consultant, ATS Insubria, Via Rossi 9, 21100, Varese, Italy
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Experimental Zooprophylactic Institute of Sicily, via G. Marinuzzi 3, 90129, Palermo, Italy
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Department of Veterinary Medicine, University of Perugia, via S. Costanzo 4, 06126, Perugia, Italy
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Department of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168, Messina, Italy
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Department of Veterinary Sciences, Polo Universitario dell'Annunziata, University of Messina, 98168, Messina, Italy
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Accepted:
05 December 2018
Published:
05 February 2019
Cite
C. Iaria, A. Ieni, I. Corti, R. Puleio, C. Brachelente, G. Mazzullo, G. Lanteri, Immunohistochemical Study of Four Fish Tumors, Journal of Aquatic Animal Health, Volume 31, Issue 1, March 2019, Pages 97–106, https://doi.org/10.1002/aah.10058
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Abstract
The present study supports the usefulness of ancillary techniques, such as immunohistochemistry, as a valid diagnostic tool in the field of fish oncology. The immunohistochemical patterns observed in four neoplasms on four individual teleosts belonging to different species are described. Cytokeratin, vimentin, actin, S100, calretinin, and Melan‐A antibodies were used. Diagnoses of papilloma in a Bream Abramis brama, fibroma in a Sand Steenbras Lithognathus mormyrus, schwannoma in a Crucian Carp Carassius carassius, and melanoma in a spontaneously inbred Xiphophorus hybrid were made. Diagnosis of tumors in fish is not always easy to carry out, and the tool provided by antibodies used on mammalian tissue is essential for obtaining definitive, unambiguous, and inexpensive identification.
© 2019 American Fisheries Society (AFS)
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