Sampling of the Intestinal Microbiota by Epithelial M Cells (original) (raw)
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
Simon GL, Gorbach SL: The human intestinal microflora. Dig Dis Sci 1986, 31(9 Suppl):147S–162S. ArticleCASPubMed Google Scholar
Fagarasan S, Muramatsu M, Suzuki K, et al.: Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science 2002, 298:1424–1427. ArticleCASPubMed Google Scholar
Peterson DA, McNulty NP, Guruge JL, Gordon JI: IgA response to symbiotic bacteria as a mediator of gut homeostasis. Cell Host Microbe 2007, 2:328–339. ArticleCASPubMed Google Scholar
Slack E, Hapfelmeier S, Stecher B, et al.: Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science 2009, 325:617–620. ArticleCASPubMed Google Scholar
Niess JH, Brand S, Gu X, et al.: CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 2005, 307:254–258. ArticleCASPubMed Google Scholar
Bockman DE, Cooper MD: Pinocytosis by epithelium associated with lymphoid follicles in the bursa of Fabricius, appendix, and Peyer’s patches. An electron microscopic study. Am J Anat 1973, 136:455–477. ArticleCASPubMed Google Scholar
Kohbata S, Yokoyama H, Yabuuchi E: Cytopathogenic effect of Salmonella typhi GIFU 10007 on M cells of murine ileal Peyer’s patches in ligated ileal loops: an ultrastructural study. Microbiol Immunol 1986, 30:1225–1237. CASPubMed Google Scholar
Autenrieth IB, Firsching R: Penetration of M cells and destruction of Peyer’s patches by Yersinia enterocolitica: an ultrastructural and histological study. J Med Microbiol 1996, 44:285–294. ArticleCASPubMed Google Scholar
Wolf JL, Rubin DH, Finberg R, et al.: Intestinal M cells: a pathway for entry of reovirus into the host. Science 1981, 212:471–472. ArticleCASPubMed Google Scholar
Jepson MA, Clark MA, Hirst BH: M cell targeting by lectins: a strategy for mucosal vaccination and drug delivery. Adv Drug Deliv Rev 2004, 56:511–525. ArticleCASPubMed Google Scholar
Clark MA, Jepson MA, Simmons NL, et al.: Differential expression of lectin-binding sites defines mouse intestinal M-cells. J Histochem Cytochem 1993, 41:1679–1687. CASPubMed Google Scholar
• Nochi T, Yuki Y, Matsumura A, et al.: A novel M cell-specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses. J Exp Med 2007, 204:2789–2796. A novel M cell-specific antibody was developed and used to successfully target antigen to M cells and induce an immune response. ArticleCASPubMed Google Scholar
Giannasca PJ, Giannasca KT, Leichtner AM, Neutra MR: Human intestinal M cells display the sialyl Lewis A antigen. Infect Immun 1999, 67:946–953. CASPubMed Google Scholar
Pappo J, Ermak TH: Uptake and translocation of fluorescent latex particles by rabbit Peyer’s patch follicle epithelium: a quantitative model for M cell uptake. Clin Exp Immunol 1989, 76:144–148. CASPubMed Google Scholar
Owen RL: Sequential uptake of horseradish peroxidase by lymphoid follicle epithelium of Peyer’s patches in the normal unobstructed mouse intestine: an ultrastructural study. Gastroenterology 1977, 72:440–451. CASPubMed Google Scholar
Frey A, Giannasca KT, Weltzin R, et al.: Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting. J Exp Med 1996, 184:1045–1059. ArticleCASPubMed Google Scholar
Isberg RR, Leong JM: Multiple beta 1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells. Cell 1990, 60:861–871. ArticleCASPubMed Google Scholar
Clark MA, Hirst BH, Jepson MA: M-cell surface beta1 integrin expression and invasin-mediated targeting of Yersinia pseudotuberculosis to mouse Peyer’s patch M cells. Infect Immun 1998, 66:1237–1243. CASPubMed Google Scholar
Karapetian O, Shakhov AN, Kraehenbuhl JP, Acha-Orbea H: Retroviral infection of neonatal Peyer’s patch lymphocytes: the mouse mammary tumor virus model. J Exp Med 1994, 180:1511–1516. ArticleCASPubMed Google Scholar
Golovkina TV, Shlomchik M, Hannum L, Chervonsky A: Organogenic role of B lymphocytes in mucosal immunity. Science 1999, 286:1965–1968. ArticleCASPubMed Google Scholar
Fotopoulos G, Harari A, Michetti P, et al.: Transepithelial transport of HIV-1 by M cells is receptor-mediated. Proc Natl Acad Sci U S A 2002, 99:9410–9414. ArticleCASPubMed Google Scholar
Sicinski P, Rowinski J, Warchol JB, et al.: Poliovirus type 1 enters the human host through intestinal M cells. Gastroenterology 1990, 98:56–58. CASPubMed Google Scholar
Helander A, Silvey KJ, Mantis NJ, et al.: The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces. J Virol 2003, 77:7964–7977. ArticleCASPubMed Google Scholar
Roy MJ, Varvayanis M: Development of dome epithelium in gut-associated lymphoid tissues: association of IgA with M cells. Cell Tissue Res, 1987, 248:645–651. ArticleCASPubMed Google Scholar
Mantis NJ, Cheung MC, Chintalacharuvu KR, et al.: Selective adherence of IgA to murine Peyer’s patch M cells: evidence for a novel IgA receptor. J Immunol 2002, 169:1844–1851. CASPubMed Google Scholar
• Terahara K, Yoshida M, Igarashi O, et al.: Comprehensive gene expression profiling of Peyer’s patch M cells, villous M-like cells, and intestinal epithelial cells. J Immunol 2008, 180:7840–7846. This article describes use of a microarray to compare gene expression between intestinal epithelial cells, PP M cells, and villous M cells. CASPubMed Google Scholar
Yu S, Lowe AW: The pancreatic zymogen granule membrane protein, GP2, binds Escherichia coli Type 1 fimbriae. BMC Gastroenterol 2009, 9:58. ArticlePubMed Google Scholar
•• Hase K, Kawano K, Nochi T, et al.: Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Nature 2009, 462:226–230. This study identified GP2 as a receptor used by M cells for sampling of bacteria. ArticleCASPubMed Google Scholar
Mach J, Hshieh T, Hsieh D, et al.: Development of intestinal M cells. Immunol Rev 2005, 206:177–189. ArticlePubMed Google Scholar
Iwatsuki H, Ogawa C, Suda M: Vimentin-positive cells in the villus epithelium of the rabbit small intestine. Histochem Cell Biol 2002, 117:363–370. ArticleCASPubMed Google Scholar
Jang MH, Kweon MN, Iwatani K, et al.: Intestinal villous M cells: an antigen entry site in the mucosal epithelium. Proc Natl Acad Sci U S A 2004, 101:6110–6115. ArticleCASPubMed Google Scholar
De Togni P, Goellner J, Ruddle NH, et al.: Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 1994, 264:703–707. ArticlePubMed Google Scholar
Kuprash DV, Tumanov AV, Liepinsh DJ, et al.: Novel tumor necrosis factor-knockout mice that lack Peyer’s patches. Eur J Immunol 2005, 35:1592–1600. ArticleCASPubMed Google Scholar
Tumanov AV, Kuprash DV, Mach JA, et al.: Lymphotoxin and TNF produced by B cells are dispensable for maintenance of the follicle-associated epithelium but are required for development of lymphoid follicles in the Peyer’s patches. J Immunol 2004, 173:86–91. CASPubMed Google Scholar
Wang J, Lopez-Fraga M, Rynko A, Lo DD: TNFR and LTbetaR agonists induce follicle-associated epithelium and M cell specific genes in rat and human intestinal epithelial cells. Cytokine 2009, 47:69–76. ArticleCASPubMed Google Scholar
•• Knoop KA, Kumar N, Butler BR, et al.: RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium. J Immunol 2009, 183:5738–5747. This study uncovered RANK signaling as an important mediator of both PP and villous M cell development. ArticleCASPubMed Google Scholar
Leibbrandt A, Penninger JM: RANK/RANKL: regulators of immune responses and bone physiology. Ann N Y Acad Sci 2008, 1143:123–150. ArticleCASPubMed Google Scholar
Kong YY, Yoshida H, Sarosi I, et al.: OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999, 397:315–323. ArticleCASPubMed Google Scholar
Taylor RT, Patel SR, Lin E, et al.: Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer’s patches. J Immunol 2007, 178:5659–5667. CASPubMed Google Scholar
• Hsieh EH, Fernandez X, Wang J, et al.: CD137 is required for M cell functional maturation but not lineage commitment. Am J Pathol 2010 (Epub ahead of print). This article describes an intermediate stage of PP M cell differentiation that is dependent on CD137 signaling.
Savidge TC, Smith MW, James PS, Aldred P: Salmonella-induced M-cell formation in germ-free mouse Peyer’s patch tissue. Am J Pathol 1991, 139:177–184. CASPubMed Google Scholar
Borghesi C, Regoli M, Bertelli E, Nicoletti C: Modifications of the follicle-associated epithelium by short-term exposure to a non-intestinal bacterium. J Pathol 1996, 180:326–332. ArticleCASPubMed Google Scholar
Smith MW, James PS, Tivey DR: M cell numbers increase after transfer of SPF mice to a normal animal house environment. Am J Pathol 1987, 128:385–389. CASPubMed Google Scholar
Lo D, Tynan W, Dickerson J, et al.: Peptidoglycan recognition protein expression in mouse Peyer’s Patch follicle associated epithelium suggests functional specialization. Cell Immunol 2003, 224:8–16. ArticleCASPubMed Google Scholar
Verbrugghe P, Waelput W, Dieriks B, et al.: Murine M cells express annexin V specifically. J Pathol 2006, 209:240–249. ArticleCASPubMed Google Scholar
Adachi S, Yoshida H, Kataoka H, Nishikawa S: Three distinctive steps in Peyer’s patch formation of murine embryo. Int Immunol 1997, 9:507–514. ArticleCASPubMed Google Scholar
Sabin AB: Properties and behavior of orally administered attenuated poliovirus vaccine. J Am Med Assoc 1957, 164:1216–1223. CASPubMed Google Scholar
Chionh YT, Wee JL, Every AL, et al.: M-cell targeting of whole killed bacteria induces protective immunity against gastrointestinal pathogens. Infect Immun 2009, 77:2962–2970. ArticleCASPubMed Google Scholar
Iweala OI, Smith DW, Matharu KS, et al.: Vaccine-induced antibody isotypes are skewed by impaired CD4 T cell and invariant NKT cell effector responses in MyD88-deficient mice. J Immunol 2009, 183:2252–2260. ArticleCASPubMed Google Scholar
Kotton CN, Hohmann EL: Enteric pathogens as vaccine vectors for foreign antigen delivery. Infect Immun 2004, 72:5535–5547. ArticleCASPubMed Google Scholar
Kerneis S, Bogdanova A, Kraehenbuhl JP, Pringault E: Conversion by Peyer’s patch lymphocytes of human enterocytes into M cells that transport bacteria. Science 1997, 277:949–952. ArticleCASPubMed Google Scholar