Local Translation and mRNA Trafficking in Axon Pathfinding (original) (raw)
Alvarez J, Giuditta A, Koenig E (2000) Protein synthesis in axons and terminals: significance for maintenance, plasticity and regulation of phenotype. With a critique of slow transport theory. Prog Neurobiol 62:1–62 ArticlePubMedCAS Google Scholar
Ando R, Hama H, Yamamoto-Hino M, Mizuno H, Miyawaki A (2002) An optical marker based on the UV-induced green-to-red photoconversion of a fluorescent protein. Proc Natl Acad Sci USA 99:12651–12656 ArticlePubMedCAS Google Scholar
Antar LN, Li C, Zhang H, Carroll RC, Bassell GJ (2006) Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses. Mol Cell Neurosci 32:37–48 ArticlePubMedCAS Google Scholar
Aronov S, Marx R, Ginzburg I (1999) Identification of 3′UTR region implicated in tau mRNA stabilization in neuronal cells. J Mol Neurosci 12:131–145 ArticlePubMedCAS Google Scholar
Aschrafi A, Schwechter AD, Mameza MG, Natera-Naranjo O, Gioio AE, Kaplan BB (2008) MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons. J Neurosci 28:12581–12590 ArticlePubMedCAS Google Scholar
Baas PW, Deitch JS, Black MM, Banker GA (1988) Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite. Proc Natl Acad Sci USA 85:8335–8339 ArticlePubMedCAS Google Scholar
Bassell GJ, Kelic S (2004) Binding proteins for mRNA localization and local translation, and their dysfunction in genetic neurological disease. Curr Opin Neurobiol 14:574–581 ArticlePubMedCAS Google Scholar
Bassell GJ, Zhang H, Byrd AL, Femino AM, Singer RH, Taneja KL, Lifshitz LM, Herman IM, Kosik KS (1998) Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. J Neurosci 18:251–265 PubMedCAS Google Scholar
Bi J, Tsai NP, Lin YP, Loh HH, Wei LN (2006) Axonal mRNA transport and localized translational regulation of kappa-opioid receptor in primary neurons of dorsal root ganglia. Proc Natl Acad Sci USA 103:19919–19924 ArticlePubMedCAS Google Scholar
Bodian D (1965) A suggestive relationship of nerve cell RNA with specific synaptic sites. Proc Natl Acad Sci USA 53:418–425 ArticlePubMedCAS Google Scholar
Bramham CR, Wells DG (2007) Dendritic mRNA: transport, translation and function. Nat Rev Neurosci 8:776–789 ArticlePubMedCAS Google Scholar
Brittis PA, Lu Q, Flanagan JG (2002) Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target. Cell 110:223–235 ArticlePubMedCAS Google Scholar
Brunet I, Weinl C, Piper M, Trembleau A, Volovitch M, Harris W, Prochiantz A, Holt C (2005) The transcription factor Engrailed-2 guides retinal axons. Nature 438:94–98 ArticlePubMedCAS Google Scholar
Campbell DS, Holt CE (2001) Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron 32:1013–1026 ArticlePubMedCAS Google Scholar
Campbell DS, Holt CE (2003) Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones. Neuron 37:939–952 ArticlePubMedCAS Google Scholar
Cox LJ, Hengst U, Gurskaya NG, Lukyanov KA, Jaffrey SR (2008) Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival. Nat Cell Biol Google Scholar
Dodd J, Morton SB, Karagogeos D, Yamamoto M, Jessell TM (1988) Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1:105–116 ArticlePubMedCAS Google Scholar
Eng H, Lund K, Campenot RB (1999) Synthesis of beta-tubulin, actin, and other proteins in axons of sympathetic neurons in compartmented cultures. J Neurosci 19:1–9 PubMedCAS Google Scholar
Eom T, Antar LN, Singer RH, Bassell GJ (2003) Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses. J Neurosci 23:10433–10444 PubMedCAS Google Scholar
Gallo G, Letourneau PC (2004) Regulation of growth cone actin filaments by guidance cues. J Neurobiol 58:92–102 ArticlePubMedCAS Google Scholar
Gingras AC, Raught B, Sonenberg N (1999) eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem 68:913–963 ArticlePubMedCAS Google Scholar
Giuditta A, Chun JT, Eyman M, Cefaliello C, Bruno AP, Crispino M (2008) Local gene expression in axons and nerve endings: the glia-neuron unit. Physiol Rev 88:515–555 ArticlePubMedCAS Google Scholar
Gu W, Pan F, Zhang H, Bassell GJ, Singer RH (2002) A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons. J Cell Biol 156:41–51 ArticlePubMedCAS Google Scholar
Guirland C, Buck KB, Gibney JA, DiCicco-Bloom E, Zheng JQ (2003) Direct cAMP signaling through G-protein-coupled receptors mediates growth cone attraction induced by pituitary adenylate cyclase-activating polypeptide. J Neurosci 23:2274–2283 Google Scholar
Hachet O, Ephrussi A (2004) Splicing of oskar RNA in the nucleus is coupled to its cytoplasmic localization. Nature 428:959–963 ArticlePubMedCAS Google Scholar
Harris WA, Holt CE, Bonhoeffer F (1987) Retinal axons with and without their somata, growing to and arborizing in the tectum of Xenopus embryos: a time-lapse video study of single fibres in vivo. Development 101:123–133 PubMedCAS Google Scholar
Hengst U, Cox LJ, Macosko EZ, Jaffrey SR (2006) Functional and selective RNA interference in developing axons and growth cones. J Neurosci 26:5727–5732 ArticlePubMedCAS Google Scholar
Hirokawa N (2006) mRNA transport in dendrites: RNA granules, motors, and tracks. J Neurosci 26:7139–7142 ArticlePubMedCAS Google Scholar
Hirokawa N, Takemura R (2005) Molecular motors and mechanisms of directional transport in neurons. Nat Rev Neurosci 6:201–214 ArticlePubMedCAS Google Scholar
Huang YS, Carson JH, Barbarese E, Richter JD (2003) Facilitation of dendritic mRNA transport by CPEB. Genes Dev 17:638–653 ArticlePubMedCAS Google Scholar
Huff T, Muller CS, Otto AM, Netzker R, Hannappel E (2001) beta-Thymosins, small acidic peptides with multiple functions. Int J Biochem Cell Biol 33:205–220 ArticlePubMedCAS Google Scholar
Huttelmaier S, Zenklusen D, Lederer M, Dictenberg J, Lorenz M, Meng X, Bassell GJ, Condeelis J, Singer RH (2005) Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature 438:512–515 ArticlePubMed Google Scholar
Jimenez-Diaz L, Geranton SM, Passmore GM, Leith JL, Fisher AS, Berliocchi L, Sivasubramaniam AK, Sheasby A, Lumb BM, Hunt SP (2008) Local translation in primary afferent fibers regulates nociception. PLoS ONE 3:e1961 ArticlePubMed Google Scholar
Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA, Nelson DL, Moses K, Warren ST (2004) Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci 7:113–117 ArticlePubMedCAS Google Scholar
Jirikowski GF, Sanna PP, Bloom FE (1990) mRNA coding for oxytocin is present in axons of the hypothalamo-neurohypophysial tract. Proc Natl Acad Sci USA 87:7400–7404 ArticlePubMedCAS Google Scholar
Kanai Y, Dohmae N, Hirokawa N (2004) Kinesin transports RNA: isolation and characterization of an RNA-transporting granule. Neuron 43:513–525 ArticlePubMedCAS Google Scholar
Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G (2004) Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc Natl Acad Sci USA 101:360–365 ArticlePubMedCAS Google Scholar
Kindler S, Wang H, Richter D, Tiedge H (2005) RNA transport and local control of translation. Annu Rev Cell Dev Biol 21:223–245 ArticlePubMedCAS Google Scholar
Kislauskis EH, Zhu X, Singer RH (1994) Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype. J Cell Biol 127:441–451 ArticlePubMedCAS Google Scholar
Knowles RB, Sabry JH, Martone ME, Deerinck TJ, Ellisman MH, Bassell GJ, Kosik KS (1996) Translocation of RNA granules in living neurons. J Neurosci 16:7812–7820 PubMedCAS Google Scholar
Koenig E (1967) Synthetic mechanisms in the axon. IV. In vitro incorporation of [3H]precursors into axonal protein and RNA. J Neurochem 14:437–446 ArticlePubMedCAS Google Scholar
Koenig E, Adams P (1982) Local protein synthesizing activity in axonal fields regenerating in vitro. J Neurochem 39:386–400 ArticlePubMedCAS Google Scholar
Koenig E, Giuditta A (1999) Protein-synthesizing machinery in the axon compartment. Neuroscience 89:5–15 ArticlePubMedCAS Google Scholar
Koenig E, Koelle GB (1960) Acetylcholinesterase regeneration in peripheral nerve after irreversible inactivation. Science 132:1249–1250 ArticlePubMedCAS Google Scholar
Koenig E, Martin R (1996) Cortical plaque-like structures identify ribosome-containing domains in the Mauthner cell axon. J Neurosci 16:1400–1411 PubMedCAS Google Scholar
Koenig E, Martin R, Titmus M, Sotelo-Silveira JR (2000) Cryptic peripheral ribosomal domains distributed intermittently along mammalian myelinated axons. J Neurosci 20:8390–8400 PubMedCAS Google Scholar
Krichevsky AM, Kosik KS (2001) Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation. Neuron 32:683–696 ArticlePubMedCAS Google Scholar
Kye MJ, Liu T, Levy SF, Xu NL, Groves BB, Bonneau R, Lao K, Kosik KS (2007) Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR. Rna 13:1224–1234 ArticlePubMedCAS Google Scholar
Lee SK, Hollenbeck PJ (2003) Organization and translation of mRNA in sympathetic axons. J Cell Sci 116:4467–4478 ArticlePubMedCAS Google Scholar
Leung KM, Holt CE (2008) Live visualization of protein synthesis in axonal growth cones by microinjection of photoconvertible Kaede into Xenopus embryos. Nat Protoc 3:1318–1327 ArticlePubMedCAS Google Scholar
Leung KM, van Horck FP, Lin AC, Allison R, Standart N, Holt CE (2006) Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1. Nat Neurosci 9:1247–1256 ArticlePubMedCAS Google Scholar
Lin AC, Holt CE (2008) Function and regulation of local axonal translation. Curr Opin Neurobiol 18:60–68 ArticlePubMedCAS Google Scholar
Litman P, Barg J, Rindzoonski L, Ginzburg I (1993) Subcellular localization of tau mRNA in differentiating neuronal cell culture: implications for neuronal polarity. Neuron 10:627–638 ArticlePubMedCAS Google Scholar
Mann F, Miranda E, Weinl C, Harmer E, Holt CE (2003) B-type Eph receptors and ephrins induce growth cone collapse through distinct intracellular pathways. J. Neurobiology 57:323–336. ArticleCAS Google Scholar
Merianda TT, Lin A, Lam J, Vuppalanchi D, Willis DE, Karin N, Holt CE, Twiss JL (2009) A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci 40:128–142 ArticlePubMedCAS Google Scholar
Min H, Turck CW, Nikolic JM, Black DL (1997) A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev 11:1023–1036 ArticlePubMedCAS Google Scholar
Ming GL, Wong ST, Henley J, Yuan XB, Song HJ, Spitzer NC, Poo MM (2002) Adaptation in the chemotactic guidance of nerve growth cones. Nature 417:411–418 ArticlePubMedCAS Google Scholar
Olink-Coux M, Hollenbeck PJ (1996) Localization and active transport of mRNA in axons of sympathetic neurons in culture. J Neurosci 16:1346–1358 PubMedCAS Google Scholar
Palacios IM, St. Johnston D (2001) Getting the message across: the intracellular localization of mRNAs in higher eukaryotes. Annu Rev Cell Dev Biol 17:569–614 ArticlePubMedCAS Google Scholar
Piper M, Anderson R, Dwivedy A, Weinl C, van Horck F, Leung KM, Cogill E, Holt C (2006) Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones. Neuron 49:215–228 ArticlePubMedCAS Google Scholar
Piper M, Salih S, Weinl C, Holt CE, Harris WA (2005) Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation. Nat Neurosci 8:179–186 ArticlePubMedCAS Google Scholar
Rehbein M, Wege K, Buck F, Schweizer M, Richter D, Kindler S (2002) Molecular characterization of MARTA1, a protein interacting with the dendritic targeting element of MAP2 mRNAs. J Neurochem 82:1039–1046 ArticlePubMedCAS Google Scholar
Richter JD (1999) Cytoplasmic polyadenylation in development and beyond. Microbiol Mol Biol Rev 63:446–456 PubMedCAS Google Scholar
Rosoff WJ, Urbach JS, Esrick MA, McAllister RG, Richards LJ, Goodhill GJ (2004) A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nat Neurosci 7:678–682 ArticlePubMedCAS Google Scholar
Ross AF, Oleynikov Y, Kislauskis EH, Taneja KL, Singer RH (1997) Characterization of a beta-actin mRNA zipcode-binding protein. Mol Cell Biol 17:2158–2165 PubMedCAS Google Scholar
Schratt GM, Tuebing F, Nigh EA, Kane CG, Sabatini ME, Kiebler M, Greenberg ME (2006) A brain-specific microRNA regulates dendritic spine development. Nature 439:283–289 ArticlePubMedCAS Google Scholar
Sossin WS, DesGroseillers L (2006) Intracellular trafficking of RNA in neurons. Traffic 7:1581–1589 ArticlePubMedCAS Google Scholar
Sotelo-Silveira JR, Calliari A, Kun A, Benech JC, Sanguinetti C, Chalar C, Sotelo JR (2000) Neurofilament mRNAs are present and translated in the normal and severed sciatic nerve. J Neurosci Res 62:65–74 ArticlePubMedCAS Google Scholar
Stein E, Tessier-Lavigne M (2001) Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex. Science 291:1928–1938 ArticlePubMedCAS Google Scholar
Steward O, Levy WB (1982) Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus. J Neurosci 2:284–291 PubMedCAS Google Scholar
Tennyson VM (1970) The fine structure of the axon and growth cone of the dorsal root neuroblast of the rabbit embryo. J Cell Biol 44:62–79 ArticlePubMedCAS Google Scholar
Tessier-Lavigne M, Goodman CS (1996) The molecular biology of axon guidance. Science 274:1123–1133 ArticlePubMedCAS Google Scholar
Tohda C, Sasaki M, Konemura T, Sasamura T, Itoh M, Kuraishi Y (2001) Axonal transport of VR1 capsaicin receptor mRNA in primary afferents and its participation in inflammation-induced increase in capsaicin sensitivity. J Neurochem 76:1628–1635 ArticlePubMedCAS Google Scholar
Trembleau A, Morales M, Bloom FE (1996) Differential compartmentalization of vasopressin messenger RNA and neuropeptide within the rat hypothalamo-neurohypophysial axonal tracts: light and electron microscopic evidence. Neuroscience 70:113–125 ArticlePubMedCAS Google Scholar
van Kesteren RE, Carter C, Dissel HM, van Minnen J, Gouwenberg Y, Syed NI, Spencer GE, Smit AB (2006) Local synthesis of actin-binding protein beta-thymosin regulates neurite outgrowth. J Neurosci 26:152–157 ArticlePubMedCAS Google Scholar
Weiner OD, Zorn AM, Krieg PA, Bittner GD (1996) Medium weight neurofilament mRNA in goldfish Mauthner axoplasm. Neurosci Lett 213:83–86 ArticlePubMedCAS Google Scholar
Wensley CH, Stone DM, Baker H, Kauer JS, Margolis FL, Chikaraishi DM (1995) Olfactory marker protein mRNA is found in axons of olfactory receptor neurons. J Neurosci 15:4827–4837 PubMedCAS Google Scholar
Willis D, Li KW, Zheng JQ, Chang JH, Smit A, Kelly T, Merianda TT, Sylvester J, van Minnen J, Twiss JL (2005) Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons. J Neurosci 25:778–791 ArticlePubMedCAS Google Scholar
Willis DE, van Niekerk EA, Sasaki Y, Mesngon M, Merianda TT, Williams GG, Kendall M, Smith DS, Bassell GJ, Twiss JL (2007) Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J Cell Biol 178:965–980 ArticlePubMedCAS Google Scholar
Wu KY, Hengst U, Cox LJ, Macosko EZ, Jeromin A, Urquhart ER, Jaffrey SR (2005) Local translation of RhoA regulates growth cone collapse. Nature 436:1020–1024 ArticlePubMedCAS Google Scholar
Yamada KM, Spooner BS, Wessells NK (1971) Ultrastructure and function of growth cones and axons of cultured nerve cells. J Cell Biol 49:614–635 ArticlePubMedCAS Google Scholar
Yao J, Sasaki Y, Wen Z, Bassell GJ, Zheng JQ (2006) An essential role for beta-actin mRNA localization and translation in Ca2+-dependent growth cone guidance. Nat Neurosci 9:1265–1273 ArticlePubMedCAS Google Scholar
Zalfa F, Achsel T, Bagni C (2006) mRNPs, polysomes or granules: FMRP in neuronal protein synthesis. Curr Opin Neurobiol 16:265–269 ArticlePubMedCAS Google Scholar
Zelenà J (1970) Ribosome-like particles in myelinated axons of the rat. Brain Res 24:359–363 ArticlePubMed Google Scholar
Zhang HL, Eom T, Oleynikov Y, Shenoy SM, Liebelt DA, Dictenberg JB, Singer RH, Bassell GJ (2001) Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility. Neuron 31:261–275 ArticlePubMedCAS Google Scholar
Zhang HL, Singer RH, Bassell GJ (1999) Neurotrophin regulation of beta-actin mRNA and protein localization within growth cones. J Cell Biol 147:59–70 ArticlePubMedCAS Google Scholar