A brain-specific microRNA regulates dendritic spine development (original) (raw)

References

  1. West, A. E., Griffith, E. C. & Greenberg, M. E. Regulation of transcription factors by neuronal activity. Nature Rev. Neurosci. 3, 921–931 (2002)
    Article CAS Google Scholar
  2. Kelleher, R. J. III, Govindarajan, A. & Tonegawa, S. Translational regulatory mechanisms in persistent forms of synaptic plasticity. Neuron 44, 59–73 (2004)
    Article CAS Google Scholar
  3. Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281–297 (2004)
    Article CAS Google Scholar
  4. He, L. & Hannon, G. J. MicroRNAs: small RNAs with a big role in gene regulation. Nature Rev. Genet. 5, 522–531 (2004)
    Article CAS Google Scholar
  5. Ambros, V. The functions of animal microRNAs. Nature 431, 350–355 (2004)
    Article CAS ADS Google Scholar
  6. Chen, C. Z., Li, L., Lodish, H. F. & Bartel, D. P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83–86 (2004)
    Article CAS ADS Google Scholar
  7. Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B. & Cohen, S. M. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila . Cell 113, 25–36 (2003)
    Article CAS Google Scholar
  8. Poy, M. N. et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432, 226–230 (2004)
    Article CAS ADS Google Scholar
  9. Chang, S., Johnston, R. J. Jr, Frokjaer-Jensen, C., Lockery, S. & Hobert, O. MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode. Nature 430, 785–789 (2004)
    Article CAS ADS Google Scholar
  10. Johnston, R. J. & Hobert, O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans . Nature 426, 845–849 (2003)
    Article CAS ADS Google Scholar
  11. Kim, J. et al. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc. Natl Acad. Sci. USA 101, 360–365 (2004)
    Article CAS ADS Google Scholar
  12. Krichevsky, A. M., King, K. S., Donahue, C. P., Khrapko, K. & Kosik, K. S. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274–1281 (2003)
    Article CAS Google Scholar
  13. Lagos-Quintana, M. et al. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12, 735–739 (2002)
    Article CAS Google Scholar
  14. Giraldez, A. J. et al. MicroRNAs regulate brain morphogenesis in zebrafish. Science 308, 833–838 (2005)
    Article CAS ADS Google Scholar
  15. Miska, E. A. et al. Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol. 5, R68 (2004)
    Article Google Scholar
  16. Sempere, L. F. et al. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 5, R13 (2004)
    Article Google Scholar
  17. Kiebler, M. A. & DesGroseillers, L. Molecular insights into mRNA transport and local translation in the mammalian nervous system. Neuron 25, 19–28 (2000)
    Article CAS Google Scholar
  18. Steward, O. & Schuman, E. M. Protein synthesis at synaptic sites on dendrites. Annu. Rev. Neurosci. 24, 299–325 (2001)
    Article CAS Google Scholar
  19. Eberwine, J., Miyashiro, K., Kacharmina, J. E. & Job, C. Local translation of classes of mRNAs that are targeted to neuronal dendrites. Proc. Natl Acad. Sci. USA 98, 7080–7085 (2001)
    Article CAS ADS Google Scholar
  20. Campbell, D. S. & Holt, C. E. Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron 32, 1013–1026 (2001)
    Article CAS Google Scholar
  21. Kang, H. & Schuman, E. M. A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science 273, 1402–1406 (1996)
    Article CAS ADS Google Scholar
  22. Zhang, X. & Poo, M. Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon. Neuron 36, 675–688 (2002)
    Article CAS Google Scholar
  23. Rao, A. & Steward, O. Evidence that protein constituents of postsynaptic membrane specializations are locally synthesized: analysis of proteins synthesized within synaptosomes. J. Neurosci. 11, 2881–2895 (1991)
    Article CAS Google Scholar
  24. Bonhoeffer, T. & Yuste, R. Spine motility. Phenomenology, mechanisms, and function. Neuron 35, 1019–1027 (2002)
    Article CAS Google Scholar
  25. Hering, H. & Sheng, M. Dendritic spines: structure, dynamics and regulation. Nature Rev. Neurosci. 2, 880–888 (2001)
    Article CAS Google Scholar
  26. Matsuzaki, M., Honkura, N., Ellis-Davies, G. C. & Kasai, H. Structural basis of long-term potentiation in single dendritic spines. Nature 429, 761–766 (2004)
    Article CAS ADS Google Scholar
  27. Nagerl, U. V., Eberhorn, N., Cambridge, S. B. & Bonhoeffer, T. Bidirectional activity-dependent morphological plasticity in hippocampal neurons. Neuron 44, 759–767 (2004)
    Article Google Scholar
  28. Zito, K., Knott, G., Shepherd, G. M., Shenolikar, S. & Svoboda, K. Induction of spine growth and synapse formation by regulation of the spine actin cytoskeleton. Neuron 44, 321–334 (2004)
    Article CAS Google Scholar
  29. Meister, G., Landthaler, M., Dorsett, Y. & Tuschl, T. Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 10, 544–550 (2004)
    Article CAS Google Scholar
  30. Hutvagner, G., Simard, M. J., Mello, C. C. & Zamore, P. D. Sequence-specific inhibition of small RNA function. PLoS Biol. 2, E98 (2004)
    Article Google Scholar
  31. Mansfield, J. H. et al. MicroRNA-responsive ‘sensor’ transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nature Genet. 36, 1079–1083 (2004)
    Article CAS Google Scholar
  32. Schratt, G. M., Nigh, E. A., Chen, W. G., Hu, L. & Greenberg, M. E. BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin–phosphatidylinositol 3-kinase-dependent pathway during neuronal development. J. Neurosci. 24, 9366–9377 (2004)
    Article Google Scholar
  33. Ji, Y., Pang, P. T., Feng, L. & Lu, B. Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons. Nature Neurosci. 8, 164–172 (2005)
    Article CAS Google Scholar
  34. Bamburg, J. R. Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu. Rev. Cell Dev. Biol. 15, 185–230 (1999)
    Article CAS Google Scholar
  35. Meng, Y. et al. Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice. Neuron 35, 121–133 (2002)
    Article CAS Google Scholar
  36. Aakalu, G., Smith, W. B., Nguyen, N., Jiang, C. & Schuman, E. M. Dynamic visualization of local protein synthesis in hippocampal neurons. Neuron 30, 489–502 (2001)
    Article CAS Google Scholar
  37. Takei, N., Kawamura, M., Hara, K., Yonezawa, K. & Nawa, H. Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulin. J. Biol. Chem. 276, 42818–42825 (2001)
    Article CAS Google Scholar
  38. Rusinov, V., Baev, V., Minkov, I. N. & Tabler, M. MicroInspector: a web tool for detection of miRNA binding sites in an RNA sequence. Nucleic Acids Res. 33, W696–W700 (2005)
    Article CAS Google Scholar
  39. John, B. et al. Human microRNA targets. PLoS Biol. 2, e363 (2004)
    Article Google Scholar
  40. McAllister, A. K., Katz, L. C. & Lo, D. C. Neurotrophins and synaptic plasticity. Annu. Rev. Neurosci. 22, 295–318 (1999)
    Article CAS Google Scholar
  41. Lu, B. BDNF and activity-dependent synaptic modulation. Learn. Mem. 10, 86–98 (2003)
    Article Google Scholar
  42. Martin, K. C. & Kosik, K. S. Synaptic tagging—who's it? Nature Rev. Neurosci. 3, 813–820 (2002)
    Article CAS Google Scholar
  43. Goetze, B., Grunewald, B., Kiebler, M. A. & Macchi, P. Coupling the iron-responsive element to GFP—an inducible system to study translation in a single living cell. Sci. STKE 2003, PL12 (2003)
    PubMed Google Scholar

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