Detecting Aβ*56 Oligomers in Brain Tissues (original) (raw)
References
Haass, C., and Selkoe, D. J. (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer’s amyloid beta-peptide. Nat Rev Mol Cell Biol8, 101–12. ArticlePubMedCAS Google Scholar
Walsh, D. M., Minogue, A. M., Sala Frigerio, C., Fadeeva, J. V., Wasco, W., and Selkoe, D. J. (2007) The APP family of proteins: similarities and differences. Biochem Soc Trans35, 416–20. ArticlePubMedCAS Google Scholar
Selkoe, D. J., and Wolfe, M. S. (2007) Presenilin: running with scissors in the membrane. Cell131, 215–21. ArticlePubMedCAS Google Scholar
Lesne, S., Koh, M. T., Kotilinek, L., Kayed, R., Glabe, C. G., Yang, A., Gallagher, M., and Ashe, K. H. (2006) A specific amyloid-beta protein assembly in the brain impairs memory. Nature440, 352–7. ArticlePubMedCAS Google Scholar
Walsh, D. M., and Selkoe, D. J. (2007) A beta oligomers – a decade of discovery. J Neurochem101, 1172–84. ArticlePubMedCAS Google Scholar
Cleary, J. P., Walsh, D. M., Hofmeister, J. J., Shankar, G. M., Kuskowski, M. A., Selkoe, D. J., and Ashe, K. H. (2005) Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function. Nat Neurosci8, 79–84. ArticlePubMedCAS Google Scholar
Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature416, 535–9. ArticlePubMedCAS Google Scholar
Shankar, G. M., Li, S., Mehta, T. H., Garcia-Munoz, A., Shepardson, N. E., Smith, I., Brett, F. M., Farrell, M. A., Rowan, M. J., Lemere, C. A., Regan, C. M., Walsh, D. M., Sabatini, B. L., and Selkoe, D. J. (2008) Amyloid-beta protein dimers isolated directly from Alzheimer’s brains impair synaptic plasticity and memory. Nat Med14, 837–42. ArticlePubMedCAS Google Scholar
Cheng, I. H., Scearce-Levie, K., Legleiter, J., Palop, J. J., Gerstein, H., Bien-Ly, N., Puolivali, J., Lesne, S., Ashe, K. H., Muchowski, P. J., and Mucke, L. (2007) Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. J Biol Chem282, 23818–28. ArticlePubMedCAS Google Scholar
Lesne, S., Kotilinek, L., and Ashe, K. H. (2008) Plaque-bearing mice with reduced levels of oligomeric amyloid-beta assemblies have intact memory function. Neuroscience151, 745–9. ArticlePubMedCAS Google Scholar