Role of Aquaporin-4 in Cerebral Edema and Stroke (original) (raw)
Amiry-Moghaddam M, Otsuka T, Hurn PD, et al. (2003a) An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proc Natl Acad Sci U S A 100:2106–2111 ArticleCAS Google Scholar
Amiry-Moghaddam M, Williamson A, Palomba M, et al. (2003b) Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of alpha-syntrophin-null mice. Proc Natl Acad Sci U S A 100:13615–13620 ArticleCAS Google Scholar
Amiry-Moghaddam M, Frydenlund DS, Ottersen OP (2004a) Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport. Neuroscience 129:999–1010 CAS Google Scholar
Amiry-Moghaddam M, Xue R, Haug FM, et al. (2004b) Alpha-syntrophin deletion removes the perivascular but not endothelial pool of aquaporin-4 at the blood—brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia. FASEB J 18:542–544 CAS Google Scholar
Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, Fini ME, Lo EH. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci. 2001 Oct 1;21(19):7724–32 PubMedCAS Google Scholar
Bereczki D, Liu M, Prado GF, Fekete I (2000) Cochrane report: a systematic review of mannitol therapy for acute ischemic stroke and cerebral parenchymal hemorrhage. Stroke 31:2719–2722 PubMedCAS Google Scholar
Binder DK, Yao X, Zador Z, Sick TJ, Verkman AS, Manley GT (2006) Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia 53:631–636 ArticlePubMed Google Scholar
Brown RC, Davis TP (2002) Calcium modulation of adherens and tight junction function: a potential mechanism for blood—brain barrier disruption after stroke. Stroke 33:1706–1711 ArticlePubMedCAS Google Scholar
Castejon OJ (1984) Formation of transendothelial channels in traumatic human brain edema. Pathol Res Pract 179:7–12 PubMedCAS Google Scholar
Connors NC, Kofuji P (2002) Dystrophin Dp71 is critical for the clustered localization of potassium channels in retinal glial cells. J Neurosci 22:4321–4327 PubMedCAS Google Scholar
Figueroa BE, Keep RF, Betz AL, Hoff JT (1998) Plasminogen activators potentiate thrombin-induced brain injury. Stroke 29:1202–1207; discussion 1208 PubMedCAS Google Scholar
Fort PE, Sene A, Pannicke T, et al. (2008) Kir4.1 and AQP4 associate with Dp71- and utrophin-DAPs complexes in specific and defined microdomains of Muller retinal glial cell membrane. Glia 56:597–610 ArticlePubMed Google Scholar
Goldstein L, Teng ZP, Zeserson E, Patel M, Regan RF (2003) Hemin induces an iron-dependent, oxidative injury to human neuron-like cells. J Neurosci Res 73:113–121 ArticlePubMedCAS Google Scholar
Hacke W, Schwab S, Horn M, Spranger M, De Georgia M, von Kummer R (1996) ‘Malignant’ middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol 53:309–315 PubMedCAS Google Scholar
Hara-Chikuma M, Verkman AS (2006) Physiological roles of glycerol-transporting aquaporins: the aquaglyceroporins. Cell Mol Life Sci 63:1386–1392 ArticlePubMedCAS Google Scholar
Hua Y, Xi G, Keep RF, Hoff JT (2000) Complement activation in the brain after experimental intracerebral hemorrhage. J Neurosurg 92:1016–1022 ArticlePubMedCAS Google Scholar
Klatzo I (1967) Presidental address. Neuropathological aspects of brain edema. J Neuropathol Exp Neurol 26:1–14 ArticlePubMedCAS Google Scholar
Lee KR, Betz AL, Keep RF, Chenevert TL, Kim S, Hoff JT (1995) Intracerebral infusion of throm-bin as a cause of brain edema. J Neurosurg 83:1045–1050 PubMedCAS Google Scholar
Manley GT, Fujimura M, Ma T, et al. (2000) Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med 6:159–163 ArticlePubMedCAS Google Scholar
Manley GT, Binder DK, Papadopoulos MC, Verkman AS (2004) New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience 129:983–991 ArticlePubMedCAS Google Scholar
Matsuoka H, Hamada R (2002) Role of thrombin in CNS damage associated with intracerebral haemorrhage: opportunity for pharmacological intervention? CNS Drugs 16:509–516 ArticlePubMedCAS Google Scholar
Nagelhus EA, Mathiisen TM, Ottersen OP (2004) Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1. Neuroscience 129:905–913 ArticlePubMedCAS Google Scholar
Neely JD, Amiry-Moghaddam M, Ottersen OP, Froehner SC, Agre P, Adams ME (2001) Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein. Proc Natl Acad Sci U S A 98:14108–14113 ArticlePubMedCAS Google Scholar
Nielsen S, Nagelhus EA, Amiry-Moghaddam M, Bourque C, Agre P, Ottersen OP (1997) Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci 17:171–180 PubMedCAS Google Scholar
Oshio K, Watanabe H, Song Y, Verkman AS, Manley GT (2005) Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1. FASEB J 19:76–78 PubMedCAS Google Scholar
Oshio K, Watanabe H, Yan D, Verkman AS, Manley GT (2006) Impaired pain sensation in mice lacking aquaporin-1 water channels. Biochem Biophys Res Commun 341:1022–1028 ArticlePubMedCAS Google Scholar
Padmawar P, Yao X, Bloch O, Manley GT, Verkman AS (2005) K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods 2:825–827 ArticlePubMedCAS Google Scholar
Papadopoulos MC, Verkman AS (2005) Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J Biol Chem 280:13906–13912 ArticlePubMedCAS Google Scholar
Papadopoulos M, Saadoun S, Krishna S, Bell B, Davies D (2002) The aquaporin-1 water channel protein is abnormally expressed in oedematous human brain tumours. J Anat 200:531–532 ArticlePubMed Google Scholar
Papadopoulos MC, Manley GT, Krishna S, Verkman AS (2004) Aquaporin-4 facilitates reabsorp-tion of excess fluid in vasogenic brain edema. FASEB J 18:1291–3 PubMedCAS Google Scholar
Peters MF, O'Brien KF, Sadoulet-Puccio HM, Kunkel LM, Adams ME, Froehner SC (1997) beta-dystrobrevin, a new member of the dystrophin family. Identification, cloning, and protein associations. J Biol Chem 272:31561–31569 ArticlePubMedCAS Google Scholar
Rash JE, Yasumura T, Hudson CS, Agre P, Nielsen S (1998) Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord. Proc Natl Acad Sci U S A 95:11981–11986 ArticlePubMedCAS Google Scholar
Ribeiro Mde C, Hirt L, Bogousslavsky J, Regli L, Badaut J (2006) Time course of aquaporin expression after transient focal cerebral ischemia in mice. J Neurosci Res 83:1231–1240 ArticlePubMedCAS Google Scholar
Rincon F, Mayer SA (2004) Novel therapies for intracerebral hemorrhage. Curr Opin Crit Care 10:94–100 ArticlePubMed Google Scholar
Saadoun S, Papadopoulos MC, Davies DC, Krishna S, Bell BA (2002) Aquaporin-4 expression is increased in oedematous human brain tumours. J Neurol Neurosurg Psychiatry 72:262–265 ArticlePubMedCAS Google Scholar
Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman AS (2005a) Impairment of angiogen-esis and cell migration by targeted aquaporin-1 gene disruption. Nature 434:786–792 ArticleCAS Google Scholar
Saadoun S, Papadopoulos MC, Watanabe H, Yan D, Manley GT, Verkman AS (2005b) Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci 118:591–598 ArticleCAS Google Scholar
Satpathy M, Gallagher P, Lizotte-Waniewski M, Srinivas SP (2004) Thrombin-induced phospho-rylation of the regulatory light chain of myosin II in cultured bovine corneal endothelial cells. Exp Eye Res 79:477–486 ArticlePubMedCAS Google Scholar
Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V (2007) Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol 6:258–268 ArticlePubMedCAS Google Scholar
Vajda Z, Pedersen M, Fuchtbauer EM, et al. (2002) Delayed onset of brain edema and mislocaliza-tion of aquaporin-4 in dystrophin-null transgenic mice. Proc Natl Acad Sci U S A 99:13131– 13136 ArticlePubMedCAS Google Scholar
Verkman AS (2005) More than just water channels: unexpected cellular roles of aquaporins. J Cell Sci 118:3225–3232 ArticlePubMedCAS Google Scholar
Wang X, Mori T, Sumii T, Lo EH (2002) Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress. Stroke 33:1882–1888 ArticlePubMedCAS Google Scholar
Weis SM, Cheresh DA (2005) Pathophysiological consequences of VEGF-induced vascular permeability. Nature 437:497–504 ArticlePubMedCAS Google Scholar
Worton R (1995) Muscular dystrophies: diseases of the dystrophin-glycoprotein complex. Science (New York, NY) 270:755–756 CAS Google Scholar
Xi G, Keep RF, Hoff JT (2006) Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol 5:53–63 ArticlePubMed Google Scholar
Yang B, Zador Z, Verkman AS (2008) Glial cell aquaporin-4 overexpression in transgenic mice accelerates cytotoxic brain swelling. J Biol Chem 283:15280–15286 ArticlePubMedCAS Google Scholar
Zador Z, Bloch O, Yao X, Manley GT (2007) Aquaporins: role in cerebral edema and brain water balance. Prog Brain Res 161:185–194 ArticlePubMedCAS Google Scholar
Zsolt Zador MD, Xiaoming Yao MD, Ph.D., and Geoffrey T Manley MD, Ph.D. Role of Aqua-porins in Non-synaptic Mechanisms of Epilepsy_Encyclopedia of Basic Epilepsy Research_Ed. Schwartzkroin, P., Elsevier, Amsterdam (In Press) Google Scholar