DETA/NONOate, a nitric oxide donor, produces antidepressant effects by promoting hippocampal neurogenesis (original) (raw)

• Abel EL, Bilitzke PJ (1990) A possible alarm substance in the forced swimming test. Physiol Behav 48:233–239
  Article PubMed CAS Google Scholar
• Alonso R, Griebel G, Pavone G, Stemmelin J, Fur GL, Soubrie P (2004) Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression. Mol Psychiatry 9:278–286
  Article PubMed CAS Google Scholar
• Bjornebekk A, Mathe AA, Brene S (2005) The antidepressant effect of running is associated with increased hippocampal cell proliferation. Int J Neuropsychopharmacol 8:357–368
  Article PubMed CAS Google Scholar
• Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, Manji HK (2000) Enhancement of hippocampal neurogenesis by lithium. J Neurochem 75:1729–1734
  Article PubMed CAS Google Scholar
• Chen JL, Li Y, Zhang RL, Katakowski M, Gautam SC, Xu YX, Lu M, Zhang ZG, Chopp M (2004) Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis. Brain Res 1005:21–28
  Article PubMed CAS Google Scholar
• Chen J, Zacharek A, Li Y, Li A, Wang L, Katakowski M, Roberts C, Lu M, Chopp M (2006) N-cadherin mediates nitric oxide-induced neurogenesis in young and retired breeder neuronspheres. Neuroscience 140:377–388
  Article PubMed CAS Google Scholar
• Czeh B, Michaelis T, Watanabe T, Frahm J, de Biurrun G, van Kampen M, Bartolomucci A, Fuchs E (2001) Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci USA 98:12796–12801
  Article PubMed CAS Google Scholar
• Dayer AG, Ford AA, Cleaver KM, Yassaee M, Cameron HA (2003) Short-term and long-term survival of new neurons in the rat dentate gyrus. J Comp Neurol 460:563–572
  Article PubMed Google Scholar
• Ducottet C, Griebel G, Belzung C (2003) Effects of the selective nonpeptide corticotropin-releasing factor receptor 1 antagonist antalarmin in the chronic mild stress model of depression in mice. Prog Neuropsychopharmacol Biol Psychiatry 27:625–631
  Article PubMed CAS Google Scholar
• Encinas JM, Vaahtokari A, Enikolopov G (2006) Fluoxetine targets early progenitor cells in the adult brain. Proc Natl Acad Sci USA 103:8233–8238
  Article PubMed CAS Google Scholar
• Ernst C, Olson AK, Pinel JP, Lam RW, Christie BR (2006) Antidepressant effects of exercise: evidence for an adult-neurogenesis hypothesis? J Psychiatry Neurosci 31:84–92
  PubMed Google Scholar
• Fabel K, Fabel K, Tam B, Kaufer D, Baiker A, Simmons N, Kuo CJ, Palmer TD (2003) VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur J Neurosci 18:2803–2812
  Article PubMed Google Scholar
• Fu W, Lu C, Mattson MP (2002) Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons. J Neuorsci 22:10710–10719
  CAS Google Scholar
• Gerdes W, Brysch W, Schlingensiepen KH, Seifert W (1992) Antisense bFGF oligodeoxynucleotides inhibit DNA synthesis of rat astrocytes. Neuroreport 3:43–46
  Article PubMed CAS Google Scholar
• Gould E, McEwen BS, Tanapat P, Galea LA, Fuchs E (1997) Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci 17:2492–2498
  PubMed CAS Google Scholar
• Griffith OW, Stuehr DJ (1995) Nitric oxide synthases: properties and catalytic mechanism. Ann Rev Physiol 57:707–736
  Article CAS Google Scholar
• Gulyaeva NV, Stepanichev MYu (1997) Biochemical correlates of individual behavior. Neurosci Behav Physiol 27:462–469
  Article PubMed CAS Google Scholar
• Harkin AJ, Bruce KH, Craft B, Paul IA (1999) Nitric oxide synthase inhibitors have antidepressant-like properties in mice. 1. Acute treatments are active in the forced swim test. Eur J Pharmacol 372:207–213
  Article PubMed CAS Google Scholar
• Harkin A, Connor TJ, Walsh M, St John N, Kelly JP (2003) Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors. Neuropharmacology 44:616–623
  Article PubMed CAS Google Scholar
• Hrabie JA, Klose JR, Wink DA (1993) New nitric oxide-releasing zwitterions derived from polyamines. J Org Chem 58:1472–1476
  Article CAS Google Scholar
• Jacobs BL, van Praag H, Gage FH (2000) Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol Psychiatry 5:262–269
  Article PubMed CAS Google Scholar
• Jefferys D, Funder J (1996) Nitric oxide modulates retention of immobility in the forced swimming test in rats. Eur J Pharmacol 295:131–135
  Article PubMed CAS Google Scholar
• Jiang W, Zhang Y, Xiao L, Van Cleemput J, Ji SP, Bai G, Zhang X (2005) Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. J Clin Invest 115:3104–3116
  Article PubMed CAS Google Scholar
• Jin K, Zhu Y, Sun Y, Mao XO, Xie L, Greenberg DA (2002) Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc Natl Acad Sci USA 99:11946–11950
  Article PubMed CAS Google Scholar
• Jin K, Sun Y, Xie L, Batteur S, Mao XO, Smelick C, Logvinova A, Greenberg DA (2003) Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice. Aging Cell 2:175–183
  Article PubMed CAS Google Scholar
• Joca SR, Guimaraes FS (2006) Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects. Psychopharmacology 185:298–305
  Article PubMed CAS Google Scholar
• Kaster MP, Ferreira PK, Santos AR, Rodrigues AL (2005) Effects of potassium channel inhibitors in the forced swimming test: possible involvement of l-arginine-nitric oxide-soluble guanylate cyclase pathway. Behav Brain Res 165:204–209
  Article PubMed CAS Google Scholar
• Lechman JF, Herman AE (2002) Maternal behavior and developmental psychopathology. Biol Psychiatry 51:27–43
  Article Google Scholar
• Lu D, Mahmood A, Zhang R, Copp M (2003) Upregulation of neurogenesis and reduction in functional deficits following administration of DEtA/NONOate, a nitric oxide donor, after traumatic brain injury in rats. J Neurosurg 99:351–361
  Article PubMed CAS Google Scholar
• Luo CX, Zhu XJ, Zhang AX, Wang W, Yang XM, Liu SH, Han X, Sun J, Zhang SG, Lu Y, Zhu DY (2005) Blockade of L-type voltage-gated Ca2+ channel inhibits ischemia-induced neurogenesis by down-regulating iNOS expression in adult mouse. J Neurochem 94:1077–1086
  Article PubMed CAS Google Scholar
• Luo CX, Zhu XJ, Zhou QG, Wang B, Wang W, Cai HH, Sun YJ, Hu M, Jiang J, Hua Y, Han X, Zhu DY (2007) Reduced neuronal nitric oxide synthase is involved in ischemia-induced hippocampal neurogenesis by up-regulating inducible nitric oxide synthase expression. J Neurochem 103:1872–1882
  Article PubMed CAS Google Scholar
• Malberg JE (2004) Implications of adult hippocampal neurogenesis in antidepressant action. J Psychiatry Neurosci 29:196–205
  PubMed Google Scholar
• Malberg JE, Eisch AJ, Nestler EJ, Duman RS (2000) Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20:9104–9110
  PubMed CAS Google Scholar
• Mallei A, Shi B, Mocchetti I (2002) Antidepressant treatments induce the expression of basic fibroblast growth factor in cortical and hippocampal neurons. Mol Pharmacol 61:1017–1024
  Article PubMed CAS Google Scholar
• Maragnoli ME, Fumagalli F, Gennarelli M, Racagni G, Riva MA (2004) Fluoxetine and olanzapine have synergistic effects in the modulation of fibroblast growth factor 2 expression within the rat brain. Biol Psychiatry 55:1095–1102
  Article PubMed CAS Google Scholar
• Moreno-López B, Romero-Grimaldi C, Noval JA, Murillo-Carretero M, Matarredona ER, Estrada C (2004) Nitric oxide is a physiological inhibitor of neurogenesis in the adult mouse subventricular zone and olfactory bulb. J Neurosci 24:85–95
  Article PubMed CAS Google Scholar
• Munoz JR, Stoutenger BR, Robinson AP, Spees JL, Prockop DJ (2005) Human stem progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice. Proc Natl Acad Sci USA 102:18171–18176
  Article PubMed CAS Google Scholar
• Nathan C (1997) Inducible nitric oxide synthase: what difference does it make? J Clin Invest 100:2417–2423
  Article PubMed CAS Google Scholar
• Packer MA, Stasiv Y, Benraiss A, Chmielnicki E, Grinberg A, Westphal H, Goldman SA, Enikolopov G (2003) Nitric oxide negatively regulates mammalian adult neurogenesis. Proc Natl Acad Sci USA 100:9566–9571
  Article PubMed CAS Google Scholar
• Palmer T, Willhoite AR, Gage FH (2000) Vascular niche for adult hippocampal neurogenesis. J Comp Neurol 425:479–494
  Article PubMed CAS Google Scholar
• Pervin S, Singh R, Gau CL, Edamatsu H, Tamanoi F, Chaudhuri G (2001) Potentiation of nitric oxide-induced apoptosis of MDA-MB-468 cells by farnesyltransferase inhibitor: implications in breast cancer. Cancer Res 61:4701–4706
  PubMed CAS Google Scholar
• Roy NS, Nakano T, Keyoung HM, Windrem M, Rashbaum WK, Alonso ML, Kang J, Peng W, Carpenter MK, Lin J, Nedergaard M, Goldman SA (2004) Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord. Nat Biotechnol 22:297–305
  Article PubMed CAS Google Scholar
• Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S, Weisstaub N, Lee J, Duman R, Arancio O, Belzung C, Hen R (2003) Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301:805–809
  Article PubMed CAS Google Scholar
• Steru L, Chermat R, Thierry B, Simon P (1985) The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 85:367–370
  Article PubMed CAS Google Scholar
• Sun Y, Jin K, Childs JT, Xie L, Mao XO, Greenberg DA (2005) Neuronal nitric oxide synthase and ischemia-induced neurogenesis. J Cereb Blood Flow Metab 25:485–492
  Article PubMed CAS Google Scholar
• Suzuki E, Yagi G, Nakaki T, Kanba S, Asai M (2001) Elevated plasma nitrate levels in depressive states. J Affect Disord 63:221–224
  Article PubMed CAS Google Scholar
• Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ (2006) Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 9:519–525
  Article PubMed CAS Google Scholar
• Tureyen K, Vemuganti R, Bowen KK, Sailor KA, Dempsey RJ (2005) EGF and FGF-2 infusion increases post-ischemic neural progenitor cell proliferation in the adult rat brain. Neurosurgery 57:1254–1263
  Article PubMed Google Scholar
• van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, Gage FH (2002) Functional neurogenesis in the adult hippocampus. Nature 415:1030–1034
  Article PubMed CAS Google Scholar
• Wainwright MS, Grundhoefer D, Sharma S, Black SM (2007) A nitric oxide donor reduces brain injury and enhances recovery of cerebral blood flow after hypoxia–ischemia in the newborn rat. Neurosci Lett 415:124–129
  Article PubMed CAS Google Scholar
• Wang SH, Zhang ZJ, Guo YJ, Teng GJ, Chen BA (2008) Hippocampal neurogenesis and behavioural studies on adult ischemic rat response to chronic mild stress. Behav Brain Res 189:9–16
  Article PubMed Google Scholar
• Warner-Schmidt JL, Duman RS (2007) VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci USA 104:4647–4752
  Article PubMed CAS Google Scholar
• Wass C, Svensson L, Fejgin K, Pålsson E, Archer T, Engel JA, Klamer D (2008) Nitric oxide synthase inhibition attenuates phencyclidine-induced disruption of cognitive flexibility. Pharmacol Biochem Behav 89:352–359
  Article PubMed CAS Google Scholar
• Wong ML, Licinio J (2001) Research and treatment approaches to depression. Nat Rev Neurosci 2:343–351
  Article PubMed CAS Google Scholar
• Workman JL, Trainor BC, Finy MS, Nelson RJ (2008) Inhibition of neuronal nitric oxide reduces anxiety-like responses to pair housing. Behav Brain Res 187:109–115
  Article PubMed CAS Google Scholar
• Yildiz F, Erden BF, Ulak G, Utkan T, Gacar N (2000) Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats. Psychopharmacology 149:41–44
  Article PubMed CAS Google Scholar
• Zacharek A, Chen J, Zhang C, Cui X, Roberts C, Jiang H, Tang H, Chopp M (2006) Nitric oxide regulates angiopoietin1/Tie2 expression after stroke. Neurosci Lett 404:28–32
  Article PubMed CAS Google Scholar
• Zhang R, Zhang L, Zhang Z, Wang Y, Lu M, Lapointe M, Chopp M (2001) A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats. Ann Neurol 50:602–611
  Article PubMed CAS Google Scholar
• Zhang RL, Wang L, Zhang L, Chen JL, Zhu ZP, Zhang ZG, Chopp M (2003) Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat. Circ Res 92:308–313
  Article PubMed CAS Google Scholar
• Zhao M, Li D, Shimazu K, Zhou YX, Lu B, Deng CX (2007) Fibroblast growth factor receptor-1 is required for long-term potentiation, memory consolidation, and neurogenesis. Biol Psychiatry 62:381–390
  Article PubMed CAS Google Scholar
• Zhou QG, Hu Y, Hua Y, Hu M, Luo CX, Han X, Zhu XJ, Wang B, Xu JS, Zhu DY (2007) Neuronal nitric oxide synthase contributes to chronic stress-induced depression in mice. J Neurochem 103:1843–1854
  Article PubMed CAS Google Scholar
• Zhu DY, Liu SH, Sun SH, Lu YM (2003) Expression of inducible nitric oxide synthase after focal cerebral ischemia stimulates neurogenesis in the adult animal dentate gyrus. J Neurosci 23:223–229
  PubMed CAS Google Scholar
• Zhu DY, Lau L, Wei JS, Liu SH, Lu YM (2004) Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci USA 101:9453–9457
  Article PubMed CAS Google Scholar
• Zhu XJ, Hua Y, Jiang J, Zhou QG, Luo CX, Han X, Lu YM, Zhu DY (2006) Neuronal nitric oxide synthase-derived nitric oxide inhibits neurogenesis in the adult dentate gyrus by down-regulating cyclic AMP response element binding protein phosphorylation. Neuroscience 141:827–835
  Article PubMed CAS Google Scholar