The SLC13 gene family of sodium sulphate/carboxylate cotransporters (original) (raw)
Aruga S, Wehrli S, Kaissling B, Moe OW, Preisig PA, Pajor AM, Alpern RJ (2000) Chronic metabolic acidosis increases NaDC-1 mRNA and protein abundance in rat kidney. Kidney Int 58:206–215 ArticleCASPubMed Google Scholar
Bai L, Pajor AM (1997) Expression cloning of NaDC-2, an intestinal Na+- or Li+-dependent dicarboxylate transporter. Am J Physiol 273:G267–G274 CASPubMed Google Scholar
Beck L, Markovich D (2000) The mouse Na+-sulfate cotransporter gene Nas1. Cloning, tissue distribution, gene structure, chromosomal assignment, and transcriptional regulation by vitamin D. J Biol Chem 275:11880–11890 CASPubMed Google Scholar
Besseghir K, Roch-Ramel F (1987) Renal excretion of drugs and other xenobiotics. Renal Physiol 10:221–241 CASPubMed Google Scholar
Burckhardt BC, Burckhardt G (2003) Transport of organic anions across the basolateral membrane of proximal tubule cells. Rev Physiol Biochem Pharmacol 146:95–158 CASPubMed Google Scholar
Burckhardt BC, Drinkuth B, Menzel C, Konig A, Steffgen J, Wright SH, Burckhardt G (2002) The renal Na+-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification. J Am Soc Nephrol 13:2628–2638 CASPubMed Google Scholar
Busch AE, Waldegger S, Herzer T, Biber J, Markovich D, Murer H, Lang F (1994) Electrogenic cotransport of Na+ and sulfate in Xenopus oocytes expressing the cloned Na+SO4 2− transport protein NaSi-1. J Biol Chem 269:12407–12409 CASPubMed Google Scholar
Chen X, Tsukaguchi H, Chen XZ, Berger UV, Hediger MA (1999) Molecular and functional analysis of SDCT2, a novel rat sodium-dependent dicarboxylate transporter. J Clin Invest 103:1159–1168 CASPubMed Google Scholar
Chen XZ, Shayakul C, Berger UV, Tian W, Hediger MA (1998) Characterization of a rat Na+-dicarboxylate cotransporter. J Biol Chem 273:20972–20981 ArticleCASPubMed Google Scholar
Dawson P, Markovich D (2002) Regulation of the mouse Nas1 gene by Vitamin D and thyroid hormone. Pflugers Arch 444:353–359 ArticleCASPubMed Google Scholar
Dawson PA, Beck L, Markovich D (2003) Hyposulfatemia, growth retardation, reduced fertility and seizures in mice lacking the sodium-sulfate cotransporter, Nas1. Proc Natl Acad Sci USA (In press)
Fei YJ, Inoue K, Ganapathy V (2003) Structural and Functional Characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. J Biol Chem 278:6136–6144 ArticleCASPubMed Google Scholar
Fernandes I, Hampson G, Cahours X, Morin P, Coureau C, Couette S, Prie D, Biber J, Murer H, Friedlander G, Silve C (1997) Abnormal sulfate metabolism in vitamin D-deficient rats. J Clin Invest 100:2196–2203 CASPubMed Google Scholar
Fernandes I, Laouari D, Tutt P, Hampson G, Friedlander G, Silve C (2001) Sulfate homeostasis, NaSi-1 cotransporter, and SAT-1 exchanger expression in chronic renal failure in rats. Kidney Int 59:210–221 CASPubMed Google Scholar
Girard JP, Baekkevold ES, Feliu J, Brandtzaeg P, Amalric F (1999) Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules. Proc Natl Acad Sci USA 96:12772–12777 ArticleCASPubMed Google Scholar
Griffith DA, Pajor AM (1999) Acidic residues involved in cation and substrate interactions in the Na+/dicarboxylate cotransporter, NaDC-1. Biochemistry 38:7524–7531 ArticleCASPubMed Google Scholar
Huang W, Wang H, Kekuda R, Fei YJ, Friedrich A, Wang J, Conway SJ, Cameron RS, Leibach FH, Ganapathy V (2000) Transport of N-acetylaspartate by the Na+-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain. J Pharmacol Exp Ther 295:392–403 Google Scholar
Inoue K, Fei YJ, Huang W, Zhuang L, Chen Z, Ganapathy V (2002) Functional identity of Drosophila melanogaster Indy as a cation-independent, electroneutral transporter for tricarboxylic acid-cycle intermediates. Biochem J 367:313–319 ArticleCASPubMed Google Scholar
Inoue K, Zhuang L, Ganapathy V (2002) Human Na+-coupled citrate transporter: primary structure, genomic organization, and transport function. Biochem Biophys Res Commun 299:465–471 ArticleCASPubMed Google Scholar
Inoue K, Zhuang L, Maddox DM, Smith SB, Ganapathy V (2002) Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain. J Biol Chem 277:39469–39476 ArticleCASPubMed Google Scholar
Kekuda R, Wang H, Huang W, Pajor AM, Leibach FH, Devoe LD, Prasad PD, Ganapathy V (1999) Primary structure and functional characteristics of a mammalian sodium-coupled high affinity dicarboxylate transporter. J Biol Chem 274:3422–3429 ArticleCASPubMed Google Scholar
Khatri IA, Kovacs SV, Forstner JF (1996) Cloning of the cDNA for a rat intestinal Na+/dicarboxylate cotransporter reveals partial sequence homology with a rat intestinal mucin. Biochim Biophys Acta 1309:58–62 ArticleCASPubMed Google Scholar
Lee A, Markovich D (2003) Cloning and characterization of the human renal Na+-sulfate cotransporter gene (NAS1) promoter. Kidney Int (In press)
Lee A, Beck L, Markovich D (2000) The human renal Na+-sulfate cotransporter (SLC13A1; hNaSi-1) cDNA and gene: organization, chromosomal localization and functional characterization. Genomics 70:354–363 Google Scholar
Leustek T, Saito K (1999) Sulfate transport and assimilation in plants. Plant Physiol 120:637–644 CASPubMed Google Scholar
Levi M, McDonald LA, Preisig PA, Alpern RJ (1991) Chronic K depletion stimulates rat renal brush-border membrane Na-citrate cotransporter. Am J Physiol 261:F767–F773 CASPubMed Google Scholar
Markovich D (2000) Molecular regulation and membrane trafficking of mammalian renal phosphate and sulphate transporters. Eur J Cell Biol 79:531–538 CASPubMed Google Scholar
Markovich D (2001) The Physiological roles and regulation of mammalian sulfate transporters. Physiol Rev 81:1499–1534 CASPubMed Google Scholar
Markovich D, Fogelis T (1999) Ontogeny of renal sulfate transporters: postnatal mRNA and protein expression. Pediatr Nephrol 13:806–811 ArticleCASPubMed Google Scholar
Markovich D, Knight D (1998) Renal Na-Si cotransporter NaSi-1 is inhibited by heavy metals. Am J Physiol 274:F283–F289 CASPubMed Google Scholar
Markovich D, Forgo J, Stange G, Biber J, Murer H (1993) Expression cloning of rat renal Na+/SO4 2− cotransport. Proc Natl Acad Sci USA 90:8073–8077 CASPubMed Google Scholar
Markovich D, Murer H, Biber J, Sakhaee K, Pak C, Levi M (1998) Dietary sulfate regulates the expression of the renal brush border Na/Si cotransporter NaSi-1. J Am Soc Nephrol 9:1568–1573 CASPubMed Google Scholar
Markovich D, Wang H, Puttaparthi K, Zajicek H, Rogers T, Murer H, Biber J, Levi M (1999) Chronic K depletion inhibits renal brush border membrane Na/sulfate cotransport. Kidney Int 55:244–251 CASPubMed Google Scholar
Markovich D, Werner A, Murer H (1999) Expression cloning with Xenopus oocytes. In: Hildebrandt F, Igarashi, P (eds) Techniques in molecular medicine. Springer, Berlin Heidelberg New York, pp 310–318
Pajor AM (1995) Sequence and functional characterization of a renal sodium/dicarboxylate cotransporter. J Biol Chem 270:5779–5785 CASPubMed Google Scholar
Pajor AM (1996) Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney. Am J Physiol 270:F642–F648 CAS Google Scholar
Pajor AM (1999) Sodium-coupled transporters for Krebs cycle intermediates. Annu Rev Physiol 61:663–682 ArticleCASPubMed Google Scholar
Pajor AM (2000) Molecular properties of sodium/dicarboxylate cotransporters. J. Membr Biol 175:1–8 ArticleCASPubMed Google Scholar
Pajor AM, Sun N (1999) Protein kinase C-mediated regulation of the renal Na+/dicarboxylate cotransporter, NaDC-1. Biochim Biophys Acta 1420:223–230 CASPubMed Google Scholar
Pajor AM, Sun NN (2000) Molecular cloning, chromosomal organization, and functional characterization of a sodium-dicarboxylate cotransporter from mouse kidney. Am J Physiol 279:F482–F490 CASPubMed Google Scholar
Pajor AM, Sun N, Bai L, Markovich D, Sule P (1998) The substrate recognition domain in the Na+/dicarboxylate and Na+/sulfate cotransporters is located in the carboxy-terminal portion of the protein. Biochim Biophys Acta 1370:98–106 ArticleCASPubMed Google Scholar
Pajor AM, Gangula R, Yao X (2001) Cloning and functional characterization of a high-affinity Na+/dicarboxylate cotransporter from mouse brain. Am J Physiol 280:C1215–C1223 CASPubMed Google Scholar
Puttaparthi K, Markovich D, Halaihel N, Wilson P, Zajicek HK, Wang H, Biber J, Murer H, Rogers T, Levi M (1999) Metabolic acidosis regulates rat renal Na-Si cotransport activity. Am J Physiol 276:C1398–C1404 CASPubMed Google Scholar
Sagawa K, DuBois DC, Almon RR, Murer H, Morris ME (1998) Cellular mechanisms of renal adaptation of sodium-dependent sulfate cotransport to altered dietary sulfate in rats. J Pharmacol Exp Ther 287:1056–1062 CASPubMed Google Scholar
Sagawa K, Murer H, Morris ME (1999) Effect of experimentally induced hypothyroidism on sulfate renal transport in rats. Am J Physiol 276:F164–F171 CASPubMed Google Scholar
Sagawa K, Darling IM, Murer H, Morris ME (2000) Glucocorticoid-Induced Alterations of Renal Sulfate Transport. J Pharmacol Exp Ther 294:658–663 CASPubMed Google Scholar
Saier MHJ, Eng BH, Fard S, Garg J, Haggerty DA, Hutchinson WJ, Jack DL, Lai EC, Liu HJ, Nusinew DP, Omar AM, Pao SS, Paulsen IT, Quan JA, Sliwinski M, Tseng TT, Wachi S, Young GB (1999) Phylogenetic characterization of novel transport protein families revealed by genome analyses. Biochim Biophys Acta 1422:1–56 CASPubMed Google Scholar
Sekine T, Cha SH, Hosoyamada M, Kanai Y, Watanabe N, Furuta Y, Fukuda K, Igarashi T, Endou H (1998) Cloning, functional characterization, and localization of a rat renal Na+-dicarboxylate transporter. Am J Physiol 275:F298–F305 CASPubMed Google Scholar
Steffgen J, Burckhardt BC, Langenberg C, Kuhne L, Muller GA, Burckhardt G, Wolff NA (1999) Expression cloning and characterization of a novel sodium-dicarboxylate cotransporter from winter flounder kidney. J Biol Chem 274:20191–20196 ArticleCASPubMed Google Scholar
Von Heijne G (1992) Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. J Mol Biol 225:487–494 PubMed Google Scholar
Wang H, Fei YJ, Kekuda R, Yang-Feng TL, Devoe LD, Leibach FH, Prasad PD, Ganapathy V (2000) Structure, function, and genomic organization of human Na+-dependent high-affinity dicarboxylate transporter. Am J Physiol 278:C1019–C1030 CASPubMed Google Scholar