Acute inflammation induced by the biopsy of mouse mammary tumors promotes the development of metastasis (original) (raw)

• Grange JM, Stanford JL, Stanford CA (2002) Campbell De Morgan’s observations on cancer, and their relevance today. J R Soc Med 95:296–299
  Article PubMed Google Scholar
• Comen EA (2012) Tracking the seed and tending the soil: evolving concepts in metastatic breast cancer. Discov Med 14:97–104
  PubMed Google Scholar
• Psaila B, Kaplan RN, Port ER, Lyden D (2006) Priming the soil for breast cancer metastasis: the pre-metastatic niche. Breast Dis 26:65–74
  PubMed CAS Google Scholar
• Paget S (1889) The distribution of secondary growths in cancer of the breast. Cancer Metastasis Rev 8:98–101
  Google Scholar
• Terzic J, Grivennikov S, Karin E, Karin M (2010) Inflammation and colon cancer. Gastroenterology 138:2101–2114 e2105
  Article PubMed CAS Google Scholar
• Ullman TA, Itzkowitz SH (2011) Intestinal inflammation and cancer. Gastroenterology 140:1807–1816
  Article PubMed CAS Google Scholar
• Roy LD, Ghosh S, Pathangey LB, Tinder TL, Gruber HE, Mukherjee P (2011) Collagen induced arthritis increases secondary metastasis in MMTV–PyV MT mouse model of mammary cancer. BMC Cancer 11:365
  Article PubMed Google Scholar
• Roy LD, Pathangey LB, Tinder TL, Schettini JL, Gruber HE, Mukherjee P (2009) Breast-cancer-associated metastasis is significantly increased in a model of autoimmune arthritis. Breast Cancer Res 11:R56
  Article PubMed Google Scholar
• Ruffell B, Affara NI, Coussens LM (2012) Differential macrophage programming in the tumor microenvironment. Trends Immunol 33:119–126
  Article PubMed CAS Google Scholar
• Jensen HK, Donskov F, Marcussen N, Nordsmark M, Lundbeck F, von der Maase H (2009) Presence of intratumoral neutrophils is an independent prognostic factor in localized renal cell carcinoma. J Clin Oncol 27:4709–4717
  Article PubMed Google Scholar
• Bellocq A, Antoine M, Flahault A, Philippe C, Crestani B, Bernaudin JF, Mayaud C, Milleron B, Baud L, Cadranel J (1998) Neutrophil alveolitis in bronchioloalveolar carcinoma: induction by tumor-derived interleukin-8 and relation to clinical outcome. Am J Pathol 152:83–92
  PubMed CAS Google Scholar
• Azab B, Bhatt VR, Phookan J, Murukutla S, Kohn N, Terjanian T, Widmann WD (2012) Usefulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients. Ann Surg Oncol 19:217–224
  Article PubMed Google Scholar
• Aspord C, Pedroza-Gonzalez A, Gallegos M, Tindle S, Burton EC, Su D, Marches F, Banchereau J, Palucka AK (2007) Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development. J Exp Med 204:1037–1047
  Article PubMed CAS Google Scholar
• Pedroza-Gonzalez A, Xu K, Wu TC, Aspord C, Tindle S, Marches F, Gallegos M, Burton EC, Savino D, Hori T et al (2011) Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J Exp Med 208:479–490
  Article PubMed CAS Google Scholar
• Ammirante M, Luo JL, Grivennikov S, Nedospasov S, Karin M (2010) B-cell-derived lymphotoxin promotes castration-resistant prostate cancer. Nature 464:302–305
  Article PubMed CAS Google Scholar
• de Visser KE, Korets LV, Coussens LM (2005) De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent. Cancer Cell 7:411–423
  Article PubMed Google Scholar
• Schioppa T, Moore R, Thompson RG, Rosser EC, Kulbe H, Nedospasov S, Mauri C, Coussens LM, Balkwill FR (2011) B regulatory cells and the tumor-promoting actions of TNF-alpha during squamous carcinogenesis. Proc Natl Acad Sci USA 108:10662–10667
  Article PubMed CAS Google Scholar
• Guy CT, Cardiff RD, Muller WJ (1992) Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 12:954–961
  PubMed CAS Google Scholar
• Poli V, Balena R, Fattori E, Markatos A, Yamamoto M, Tanaka H, Ciliberto G, Rodan GA, Constantini F (1994) Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion. EMBO J 13:1189–1196
  PubMed CAS Google Scholar
• Neveu W, Allard JB, Dienz O, Wargo MJ, Ciliberto G, Whittaker LA, Rincon M (2009) IL-6 is required for airway mucus production induced by inhaled fungal allergens. J Immunol 183:1732–1738
  Article PubMed CAS Google Scholar
• Allard JB, Poynter ME, Marr KA, Cohn L, Rincon M, Whittaker LA (2006) Aspergillus fumigatus generates an enhanced Th2-biased immune response in mice with defective cystic fibrosis transmembrane conductance regulator. J Immunol 177:5186–5194
  PubMed CAS Google Scholar
• Rincon M, Broadwater G, Harris L, Crocker A, Weaver D, Dressler H, Berry D, Sutton L, Michaelson R, Messino M et al (2006) Interleukin-6 and multidrug resistance protein 1 (PGP-1) expression and response to paclitaxel in women with metastatic breast cancer: results of cancer and leukemia group B trial 159806. Breast Cancer Res Treat 100:301–308
  Article PubMed CAS Google Scholar
• Baribault H, Wilson-Heiner M, Muller W, Penner J, Bakhiet N (1997) Functional analysis of mouse keratin 8 in polyoma middle T-induced mammary gland tumours. Transgenic Res 6:359–367
  Article PubMed CAS Google Scholar
• Waldner MJ, Foersch S, Neurath MF (2012) Interleukin-6–a key regulator of colorectal cancer development. Int J Biol Sci 8:1248–1253
  Article PubMed CAS Google Scholar
• He G, Karin M (2011) NF-kappaB and STAT3—key players in liver inflammation and cancer. Cell Res 21:159–168
  Article PubMed CAS Google Scholar
• Tawara K, Oxford JT, Jorcyk CL (2011) Clinical significance of interleukin (IL)-6 in cancer metastasis to bone: potential of anti-IL-6 therapies. Cancer Manag Res 3:177–189
  PubMed CAS Google Scholar
• Shakhar G, Ben-Eliyahu S (2003) Potential prophylactic measures against postoperative immunosuppression: could they reduce recurrence rates in oncological patients? Ann Surg Oncol 10:972–992
  Article PubMed Google Scholar
• Coussens LM, Zitvogel L, Palucka AK (2013) Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science 339:286–291
  Article PubMed CAS Google Scholar
• Foekens JA, Ries C, Look MP, Gippner-Steppert C, Klijn JG, Jochum M (2003) The prognostic value of polymorphonuclear leukocyte elastase in patients with primary breast cancer. Cancer Res 63:337–341
  PubMed CAS Google Scholar
• Foekens JA, Ries C, Look MP, Gippner-Steppert C, Klijn JG, Jochum M (2003) Elevated expression of polymorphonuclear leukocyte elastase in breast cancer tissue is associated with tamoxifen failure in patients with advanced disease. Br J Cancer 88:1084–1090
  Article PubMed CAS Google Scholar
• Houghton AM (2010) The paradox of tumor-associated neutrophils: fueling tumor growth with cytotoxic substances. Cell Cycle 9:1732–1737
  Article PubMed CAS Google Scholar
• Rincon M (2012) Interleukin-6: from an inflammatory marker to a target for inflammatory diseases. Trends Immunol 33:571–577
  Article PubMed CAS Google Scholar
• Grivennikov SI, Karin M (2011) Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann Rheum Dis 70(Suppl 1):i104–i108
  Article PubMed CAS Google Scholar
• Sansone P, Bromberg J (2012) Targeting the interleukin-6/Jak/stat pathway in human malignancies. J Clin Oncol 30:1005–1014
  Article PubMed CAS Google Scholar
• Rokavec M, Wu W, Luo JL (2012) IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis. Mol Cell 45:777–789
  Article PubMed CAS Google Scholar
• Rose-John S (2012) IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6. Int J Biol Sci 8:1237–1247
  Article PubMed CAS Google Scholar