The super super-healing MRL mouse strain (original) (raw)

References

• Abdullah I, Lepore J J, Epstein J A, Parmacek M S, Gruber P J (2005). MRL mice fail to heal the heart in response to ischemia-reperfusion injury. Wound Repair and Regeneration, 13: 205–208
  Article PubMed Google Scholar
• Adachi M, Watanabe-Fukunaga R, Nagata S (1993). Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice. Proc Natl Acad Sci USA, 90(5): 1756–1760
  Article PubMed CAS Google Scholar
• Alexakis C, Partridge T, Bou-Gharios G (2007). Implication of the satellite cell in dystrophic muscle fibrosis: a self-perpetuating mechanism of collagen overproduction. Am J Physiol Cell Physiol, 293(2): C661–C669
  Article PubMed CAS Google Scholar
• Alleva D G, Kaser S B, Beller D I (1997). Aberrant cytokine expression and autocrine regulation characterize macrophages from young MRL+/+ and NZB/W F1 lupus-prone mice. J Immunol, 159: 5610–5619
  PubMed CAS Google Scholar
• Anversa P, Rota M, Urbanek K, Hosoda T, Sonnenblick E H, Leri A, Kajstura J, Bolli R (2005). Myocardial aging-a stem cell problem. Basic Res Cardiol, 100(6): 482–493
  Article PubMed CAS Google Scholar
• Arthur L M, Demarest R M, Clark L, Gourevitch D, Bedelbaeva K, Anderson R, Snyder A, Capobianco A J, Lieberman P, Feigenbaum L, Heber-Katz E (2010). Epimorphic regeneration in mice is p53-independent. Cell Cycle, 9(18): 3667–3673
  Article PubMed CAS Google Scholar
• Ashcroft G S, Yang X, Glick A B, Weinstein M, Letterio J L, Mizel D E, Anzano M, Greenwell-Wild T, Wahl S M, Deng C (1999). Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response. Nat Cell Biol, 1(5): 260–266
  Article PubMed CAS Google Scholar
• Baker K L, Daniels S B, Lennington J B, Lardaro T, Czap A, Notti R Q, Cooper O, Isacson O, Frasca S Jr, Conover J C (2006). Neuroblast protuberances in the subventricular zone of the regenerative MRL/ MpJ mouse. J Comp Neurol, 498(6): 747–761
  Article PubMed Google Scholar
• Balomenos D, Martin-Caballero J, Garcia M I, Prieto I, Flores J M, Serrano M, Martinez A C (2000). The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development. Nat Med, 6(2): 171–176
  Article PubMed CAS Google Scholar
• Balu D T, Hodes G E, Anderson B T, Lucki I (2009). Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of chronic antidepressant treatments. Neuropsychopharmacology, 34(7): 1764–1773
  Article PubMed CAS Google Scholar
• Beare A H, Metcalfe A D, Ferguson M W (2006). Location of injury influences the mechanisms of both regeneration and repair within the MRL/MpJ mouse. J Anat, 209(4): 547–559
  Article PubMed Google Scholar
• Bedelbaeva K, Gourevitch D, Clark L, Chen P, Leferovich J M, Heber-Katz E (2004). The MRL mouse heart healing response shows donor dominance in allogeneic fetal liver chimeric mice. Cloning Stem Cells, 6(4): 352–363
  Article PubMed CAS Google Scholar
• Bedelbaeva K, Snyder A, Gourevitch D, Clark L, Zhang X M, Leferovich J, Cheverud J M, Lieberman P, Heber-Katz E (2010). Lack of p21 expression links cell cycle control and appendage regeneration in mice. Proc Natl Acad Sci USA, 107(13): 5845–5850
  Article PubMed CAS Google Scholar
• Blankenhorn E P, Bryan G, Kossenkov A V, Clark L D, Zhang X M, Chang C, Horng W, Pletscher L S, Cheverud JM, Showe L C (2009). Genetic loci that regulate healing and regeneration in LG/J and SM/J mice. Mammalian Genome, 20: 720–733
  Article PubMed CAS Google Scholar
• Blankenhorn E P, Troutman S, Clark L D, Zhang X M, Chen P, Heber-Katz E (2003). Sexually dimorphic genes regulate healing and regeneration in MRL mice. Mamm Genome, 14(4): 250–260
  Article PubMed Google Scholar
• Buckley G, Metcalfe A D, Ferguson M W (2011). Peripheral nerve regeneration in the MRL/MpJ ear wound model. J Anat, 218(2): 163–172
  Article PubMed Google Scholar
• Bulfield G, Siller W G, Wight P A, Moore K J (1984). X chromosome-linked muscular dystrophy (mdx) in the mouse. Proc Natl Acad Sci USA, 81(4): 1189–1192
  Article PubMed CAS Google Scholar
• Chadwick R B, Bu L, Yu H, Hu Y, Wergedal J E, Mohan S, Baylink D J (2007). Digit tip regrowth and differential gene expression in MRL/ Mpj, DBA/2, and C57BL/6 mice. Wound Repair and Regeneration, 15: 275–284
  Article PubMed Google Scholar
• Chaudhuri T, Rehfeldt F, Sweeney H L, Discher D E (2010). Preparation of collagen-coated gels that maximize in vitro myogenesis of stem cells by matching the lateral elasticity of in vivo muscle. Methods Mol Biol, 621: 185–202
  Article PubMed CAS Google Scholar
• Cimini M, Fazel S, Fujii H, Zhou S, Tang G, Weisel R D, Li R K (2008). The MRL mouse heart does not recover ventricular function after a myocardial infarction. Cardiovascular pathology: the official journal of the Society for Cardiovascular Pathology 17, 32–39
  CAS Google Scholar
• Clark L D, Clark R K, Heber-Katz E (1998). A new murine model for mammalian wound repair and regeneration. Clin Immunol Immunopathol, 88(1): 35–45
  Article PubMed CAS Google Scholar
• Colwell A S, Krummel T M, Kong W, Longaker M T, Lorenz H P (2006). Skin wounds in the MRL/MPJ mouse heal with scar. Wound Repair and Regeneration, 14: 81–90
  Article PubMed Google Scholar
• Cowin A J, Brosnan M P, Holmes T M, Ferguson M W (1998). Endogenous inflammatory response to dermal wound healing in the fetal and adult mouse. Developmental Dynamics, 212: 385–393
  Article PubMed CAS Google Scholar
• Cullen MJ, Jaros E (1988). Ultrastructure of the skeletal muscle in the X chromosome-linked dystrophic (mdx) mouse. Comparison with Duchenne muscular dystrophy. Acta Neuropathol, 77(1): 69–81
  Article PubMed CAS Google Scholar
• Darby I A, Bisucci T, Pittet B, Garbin S, Gabbiani G, Desmouliere A (2002). Skin flap-induced regression of granulation tissue correlates with reduced growth factor and increased metalloproteinase expression. J Pathol, 197: 117–127
  Article PubMed CAS Google Scholar
• Davis T A, Amare M, Naik S, Kovalchuk A L, Tadaki D (2007). Differential cutaneous wound healing in thermally injured MRL/MPJ mice. Wound Repair and Regeneration, 15: 577–588
  Article PubMed Google Scholar
• Davis T A, Longcor J D, Hicok K C, Lennon G G (2005). Prior injury accelerates subsequent wound closure in a mouse model of regeneration. Cell Tissue Res, 320(3): 417–426
  Article PubMed Google Scholar
• Desmouliere A, Chaponnier C, Gabbiani G (2005). Tissue repair, contraction, and the myofibroblast. Wound Repair and Regeneration, 13: 7–12
  Article PubMed Google Scholar
• Donnelly R P, Levine J, Hartwell D Q, Frendl G, Fenton M J, Beller D I (1990). Aberrant regulation of IL-1 expression in macrophages from young autoimmune-prone mice. J Immunol, 145: 3231–3239
  PubMed CAS Google Scholar
• Fawcett J W, Asher R A (1999). The glial scar and central nervous system repair. Brain Res Bull, 49(6): 377–391
  Article PubMed CAS Google Scholar
• Ferguson M W, O’Kane S (2004). Scar-free healing: from embryonic mechanisms to adult therapeutic intervention. Philos Trans R Soc Lond B Biol Sci, 359(1445): 839–850
  Article PubMed CAS Google Scholar
• Fitzgerald J, Rich C, Burkhardt D, Allen J, Herzka A S, Little C B (2008). Evidence for articular cartilage regeneration in MRL/MpJ mice. Osteoarthritis and cartilage / OARS. Osteoarthritis Research Society, 16(11): 1319–1326
  Article CAS Google Scholar
• Gawronska-Kozak B (2004). Regeneration in the ears of immunodeficient mice: identification and lineage analysis of mesenchymal stem cells. Tissue Eng, 10: 1251–1265
  PubMed CAS Google Scholar
• Goss R J (1980). Prospects of regeneration in man. Clin Orthop Relat Res: 270–282
• Gourevitch D, Clark L, Chen P, Seitz A, Samulewicz S J, Heber-Katz E (2003). Matrix metalloproteinase activity correlates with blastema formation in the regenerating MRL mouse ear hole model. Developmental Dynamics, 226: 377–387
  Article PubMed CAS Google Scholar
• Gourevitch D L, Clark L, Bedelbaeva K, Leferovich J, Heber-Katz E (2009). Dynamic changes after murine digit amputation: the MRL mouse digit shows waves of tissue remodeling, growth, and apoptosis. Wound Repair and Regeneration, 17: 447–455
  Article PubMed Google Scholar
• Grisel P, Meinhardt A, Lehr H A, Kappenberger L, Barrandon Y, Vassalli G (2008). The MRL mouse repairs both cryogenic and ischemic myocardial infarcts with scar. Cardiovascular Pathology, 17: 14–22
  Article PubMed CAS Google Scholar
• Hampton D W, Seitz A, Chen P, Heber-Katz E, Fawcett J W (2004). Altered CNS response to injury in the MRL/MpJ mouse. Neuroscience, 127(4): 821–832
  Article PubMed CAS Google Scholar
• Han M, Yang X, Taylor G, Burdsal C A, Anderson R A, Muneoka K (2005). Limb regeneration in higher vertebrates: developing a roadmap. Anat Rec B New Anat, 287B(1): 14–24
  Article Google Scholar
• Harty M, Neff AW, King M W, Mescher A L (2003). Regeneration or scarring: an immunologic perspective. Developmental Dynamics, 226: 268–279
  Article PubMed Google Scholar
• Havran WL, Allison J P (1988). Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors. Nature, 335(6189): 443–445
  Article PubMed CAS Google Scholar
• Heber-Katz E (1999). The regenerating mouse ear. Semin Cell Dev Biol, 10(4): 415–419
  Article PubMed CAS Google Scholar
• Heber-Katz E, Chen P, Clark L, Zhang X M, Troutman S, Blankenhorn E P (2004a). Regeneration in MRL mice: further genetic loci controlling the ear hole closure trait using MRL and M.m. Castaneus mice. Wound Repair and Regeneration, 12: 384–392
  Article PubMed Google Scholar
• Heber-Katz E, Leferovich J, Bedelbaeva K, Gourevitch D, Clark L (2004b). The scarless heart and the MRL mouse. Philos Trans R Soc Lond B Biol Sci, 359(1445): 785–793
  Article PubMed CAS Google Scholar
• Heber-Katz E, Leferovich J, Bedelbaeva K, Gourevitch D, Clark L (2006). Conjecture: Can continuous regeneration lead to immortality? Studies in the MRL mouse. Rejuvenation Res, 9(1): 3–9
  Article PubMed Google Scholar
• Heydemann A, Ceco E, Lim J E, Hadhazy M, Ryder P, Moran J L, Beier D R, Palmer A A, McNally E M (2009). Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest, 119(12): 3703–3712
  Article PubMed CAS Google Scholar
• Hong Y, Cervantes R B, Tichy E, Tischfield J A, Stambrook P J (2007). Protecting genomic integrity in somatic cells and embryonic stem cells. Mutat Res, 614(1–2): 48–55
  PubMed CAS Google Scholar
• Hopkinson-Woolley J, Hughes D, Gordon S, Martin P (1994). Macrophage recruitment during limb development and wound healing in the embryonic and foetal mouse. J Cell Sci, 107(Pt 5): 1159–1167
  PubMed Google Scholar
• Ito M R, Ono M, Itoh J, Nose M (2003). Bone marrow cell transfer of autoimmune diseases in a MRL strain of mice with a deficit in functional Fas ligand: dissociation of arteritis from glomerulone-phritis. Pathol Int, 53(8): 518–524
  Article PubMed Google Scholar
• Kench J A, Russell D M, Fadok VA, Young S K, Worthen G S, Jones-Carson J, Henson J E, Henson P M, Nemazee D (1999). Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse. Clin Immunol, 92(3): 300–310
  Article PubMed CAS Google Scholar
• Leader B, Leder P (2000). Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system. Mech Dev, 93(1–2): 221–231
  Article PubMed CAS Google Scholar
• Leferovich J M, Bedelbaeva K, Samulewicz S, Zhang X M, Zwas D, Lankford E B, Heber-Katz E (2001). Heart regeneration in adult MRL mice. Proc Natl Acad Sci USA, 98(17): 9830–9835
  Article PubMed CAS Google Scholar
• Li X, Mohan S, Gu W, Baylink D J (2001). Analysis of gene expression in the wound repair/regeneration process. Mammalian Genome, 12: 52–59
  Article PubMed CAS Google Scholar
• Li X, Mohan S, Gu W, Miyakoshi N, Baylink D J (2000). Differential protein profile in the ear-punched tissue of regeneration and nonregeneration strains of mice: a novel approach to explore the candidate genes for soft-tissue regeneration. Biochim Biophys Acta, 1524(2–3): 102–109
  Article PubMed CAS Google Scholar
• Liu H, Ding Q, Yang K, Zhang T, Li G, Wu G (2011). Meta-analysis of systemic lupus erythematosus and the risk of cervical neoplasia. Rheumatology, 50(2): 343–348
  Article PubMed Google Scholar
• Mann C J, Perdiguero E, Kharraz Y, Aguilar S, Pessina P, Serrano A L, Munoz-Canoves P (2011). Aberrant repair and fibrosis development in skeletal muscle. Skeletal muscle 1, 21
  Article PubMed Google Scholar
• Masinde G, Li X, Baylink D J, Nguyen B, Mohan S (2005). Isolation of wound healing/regeneration genes using restrictive fragment differential display-PCR in MRL/MPJ and C57BL/6 mice. Biochem Biophys Res Commun, 330(1): 117–122
  Article PubMed CAS Google Scholar
• Masinde G L, Li X, Gu W, Davidson H, Mohan S, Baylink D J (2001). Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population. Genome Res, 11(12): 2027–2033
  Article PubMed CAS Google Scholar
• McBrearty B A, Clark L D, Zhang XM, Blankenhorn E P, Heber-Katz E (1998). Genetic analysis of a mammalian wound-healing trait. Proc Natl Acad Sci USA, 95(20): 11792–11797
  Article PubMed CAS Google Scholar
• Metcalfe A D, Willis H, Beare A, Ferguson M W (2006). Characterizing regeneration in the vertebrate ear. J Anat, 209(4): 439–446
  Article PubMed Google Scholar
• Michalopoulos G K, DeFrances M C (1997). Liver regeneration. Science, 276(5309): 60–66
  Article PubMed CAS Google Scholar
• Midwood K S, Williams L V, Schwarzbauer J E (2004). Tissue repair and the dynamics of the extracellular matrix. Int J Biochem Cell Biol, 36(6): 1031–1037
  Article PubMed CAS Google Scholar
• Moseley F L, Faircloth M E, Lockwood W, Marber M S, Bicknell K A, Valasek P, Brooks G (2011). Limitations of the MRL mouse as a model for cardiac regeneration. J Pharm Pharmacol, 63(5): 648–656
  Article PubMed CAS Google Scholar
• Namazi M R, Fallahzadeh M K, Schwartz R A (2011). Strategies for prevention of scars: what can we learn from fetal skin? Int J Dermatol, 50(1): 85–93
  Article PubMed Google Scholar
• Naseem R H, Meeson A P, Michael Dimaio J, White M D, Kallhoff J, Humphries C, Goetsch S C, DeWindt L J,WilliamsMA, Garry MG (2007). Reparative myocardial mechanisms in adult C57BL/6 and MRL mice following injury. Physiol Genomics, 30(1): 44–52
  Article PubMed CAS Google Scholar
• Naviaux R K, Le T P, Bedelbaeva K, Leferovich J, Gourevitch D, Sachadyn P, Zhang X M, Clark L, Heber-Katz E (2009). Retained features of embryonic metabolism in the adult MRL mouse. Mol Genet Metab, 96(3): 133–144
  Article PubMed CAS Google Scholar
• Oh Y S, Thomson L E, Fishbein M C, Berman D S, Sharifi B, Chen P S (2004). Scar formation after ischemic myocardial injury in MRL mice. Cardiovascular Pathology, 13: 203–206
  Article PubMed Google Scholar
• Peled Z M, Phelps E D, Updike D L, Chang J, Krummel T M, Howard E W, Longaker M T (2002). Matrix metalloproteinases and the ontogeny of scarless repair: the other side of the wound healing balance. Plast Reconstr Surg, 110(3): 801–811
  Article PubMed Google Scholar
• Peng S L, Madaio M P, Craft J (1996). Systemic autoimmunity in LG/J mice. Immunol Lett, 53(2–3): 153–155
  Article PubMed CAS Google Scholar
• Potter P K, Cortes-Hernandez J, Quartier P, Botto M, Walport M J (2003). Lupus-prone mice have an abnormal response to thioglycolate and an impaired clearance of apoptotic cells. J Immunol, 170: 3223–3232
  PubMed CAS Google Scholar
• Rajnoch C, Ferguson S, Metcalfe A D, Herrick S E, Willis H S, Ferguson M W (2003). Regeneration of the ear after wounding in different mouse strains is dependent on the severity of wound trauma. Developmental Dynamics, 226: 388–397
  Article PubMed Google Scholar
• Rao N, Jhamb D, Milner D J, Li B, Song F, Wang M, Voss S R, Palakal M, King M W, Saranjami B, Nye H L D, Cameron J, Stocum D L (2009). Proteomic analysis of blastema formation in regenerating axolotl limbs. BMC Biol, 7(1): 83
  Article PubMed Google Scholar
• Robey T E, Murry C E (2008). Absence of regeneration in the MRL/MpJ mouse heart following infarction or cryoinjury. Cardiovascular Pathology, 17: 6–13
  Article PubMed CAS Google Scholar
• Sacco A, Doyonnas R, Kraft P, Vitorovic S, Blau H M (2008). Self-renewal and expansion of single transplanted muscle stem cells. Nature, 456(7221): 502–506
  Article PubMed CAS Google Scholar
• Sachadyn P, Zhang XM, Clark L D, Naviaux R K, Heber-Katz E (2008). Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse. Mitochondrion, 8(5–6): 358–366
  Article PubMed CAS Google Scholar
• Saika S (2007). Yin and yang in cytokine regulation of corneal wound healing: roles of TNF-alpha. Cornea, 26(Supplement 1): S70–S74
  Article PubMed Google Scholar
• Santiago-Raber M L, Lawson B R, Dummer W, Barnhouse M, Koundouris S, Wilson C B, Kono D H, Theofilopoulos A N (2001). Role of cyclin kinase inhibitor p21 in systemic autoimmunity. J Immunol, 167: 4067–4074
  PubMed CAS Google Scholar
• Shah M, Foreman D M, Ferguson M W (1995). Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J Cell Sci, 108(Pt 3): 985–1002
  PubMed CAS Google Scholar
• Stocum D L (1984). The urodele limb regeneration blastema. Determination and organization of the morphogenetic field. Differentiation, 27(1–3): 13–28
  CAS Google Scholar
• Stocum, D.L., and Crawford, K. (1987). Use of retinoids to analyze the cellular basis of positional memory in regenerating amphibian limbs. Biochemistry and Cell Biology, 65: 750–761
  Article PubMed CAS Google Scholar
• Tassava R A (1983). Limb regeneration to digit stages occurs in well-fed adult newts after hypophysectomy. J Exp Zool, 225(3): 433–441
  Article PubMed CAS Google Scholar
• Theofilopoulos A N, Dixon F J (1985). Murine models of systemic lupus erythematosus. Adv Immunol, 37: 269–290
  Article PubMed CAS Google Scholar
• Thuret S, Toni N, Aigner S, Yeo G W, Gage F H (2009). Hippocampus-dependent learning is associated with adult neurogenesis in MRL/MpJ mice. Hippocampus, 19(7): 658–669
  Article PubMed CAS Google Scholar
• Tolba R H, Schildberg F A, Decker D, Abdullah Z, Buttner R, Minor T, von Ruecker A (2010). Mechanisms of improved wound healing in Murphy Roths Large (MRL) mice after skin transplantation. Wound Repair Regen, 18(6): 662–670
  Article PubMed Google Scholar
• Torres V E, Leof E B (2011). Fibrosis, regeneration, and aging: playing chess with evolution. J Am Soc Nephrol, 22(8): 1393–1396
  Article PubMed CAS Google Scholar
• Ueno M, Lyons B L, Burzenski L M, Gott B, Shaffer D J, Roopenian D C, Shultz L D (2005). Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature. Invest Ophthalmol Vis Sci, 46(11): 4097–4106
  Article PubMed Google Scholar
• Vorotnikova E, McIntosh D, Dewilde A, Zhang J, Reing J E, Zhang L, Cordero K, Bedelbaeva K, Gourevitch D, Heber-Katz E (2010). Extracellular matrix-derived products modulate endothelial and progenitor cell migration and proliferation in vitro and stimulate regenerative healing in vivo. Matrix Biology, 29: 690–700
  Article PubMed CAS Google Scholar
• Wandstrat A, Wakeland E (2001). The genetics of complex autoimmune diseases: non-MHC susceptibility genes. Nat Immunol, 2(9): 802–809
  Article PubMed CAS Google Scholar
• Ward B D, Furman B D, Huebner J L, Kraus V B, Guilak F, Olson S A (2008). Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse. Arthritis Rheum, 58(3): 744–753
  Article PubMed Google Scholar
• Watson M L, Rao J K, Gilkeson G S, Ruiz P, Eicher E M, Pisetsky D S, Matsuzawa A, Rochelle J M, Seldin M F (1992). Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med, 176(6): 1645–1656
  Article PubMed CAS Google Scholar
• Whitby D J, Ferguson M W (1991). Immunohistochemical localization of growth factors in fetal wound healing. Dev Biol, 147(1): 207–215
  Article PubMed CAS Google Scholar
• Williams B O, Insogna K L (2009). Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone. Journal of Bone and Mineral Research, 24: 171–178
  Article PubMed CAS Google Scholar
• Xu H, Christmas P, Wu X R, Wewer U M, Engvall E (1994). Defective muscle basement membrane and lack of M-laminin in the dystrophic dy/dy mouse. Proc Natl Acad Sci USA, 91(12): 5572–5576
  Article PubMed CAS Google Scholar
• Yu H, Baylink D J, Masinde G L, Li R, Nguyen B, Davidson HM, Xu S, Mohan S (2007). Mouse chromosome 9 quantitative trait loci for soft tissue regeneration: congenic analysis and fine mapping. Wound Repair and Regeneration, 15: 922–927
  Article PubMed Google Scholar
• Yu H, Mohan S, Masinde GL, Baylink D J (2005). Mapping the dominant wound healing and soft tissue regeneration QTL in MRL x CAST. Mammalian Genome, 16: 918–924
  Article PubMed CAS Google Scholar
• Yuan R, Tsaih S W, Petkova S B, Marin de Evsikova C, Xing S, Marion MA, Bogue MA, Mills K D, Peters L L, Bult C J, et al (2009). Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell, 8(3): 277–287
  Article PubMed CAS Google Scholar
• Ziv E, Hu D (2011). Genetic variation in insulin/IGF-1 signaling pathways and longevity. Ageing Res Rev, 10(2): 201–204
  Article PubMed CAS Google Scholar

Download references