Phagocytosis promotes programmed cell death in C. elegans (original) (raw)
References
Ellis, H. M. & Horvitz, H. R. Genetic control of programmed cell death in the nematode C. elegans. Cell44, 817–829 (1986). ArticleCAS Google Scholar
Conradt, B. & Horvitz, H. R. The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell93, 519–529 (1998). ArticleCAS Google Scholar
Hedgecock, E. M., Sulston, J. E. & Thomson, J. N. Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans. Science220, 1277–1279 (1983). ArticleADSCAS Google Scholar
Ellis, R. E., Jacobson, D. M. & Horvitz, H. R. Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics129, 79–94 (1991). CAS Google Scholar
Chung, S., Gumienny, T. L., Hengartner, M. O. & Driscoll, M. A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans. Nature Cell Biol.2, 931–937 (2000). ArticleCAS Google Scholar
Zhou, Z., Hartwieg, E. & Horvitz, H. R. CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans. Cell104, 43–56 (2001). ArticleCAS Google Scholar
Yuan, J., Shaham, S., Ledoux, S., Ellis, H. M. & Horvitz, H. R. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell75, 641–652 (1993). ArticleCAS Google Scholar
Vaux, D. L. & Korsmeyer, S. J. Cell death in development. Cell96, 245–254 (1999). ArticleCAS Google Scholar
Sulston, J. E. & Horvitz, H. R. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev. Biol.56, 110–156 (1977). ArticleCAS Google Scholar
Robertson, A. M. G. & Thomson, J. N. Morphology of programmed cell death in the ventral nerve cord of C. elegans larvae. J. Embryol. Exp. Morphol.67, 89–100 (1982). Google Scholar
Metzstein, M. M., Stanfield, G. M. & Horvitz, H. R. Genetics of programmed cell death in C. elegans: Past, present and future. Trends Genet.14, 410–416 (1998). ArticleCAS Google Scholar
Albert, M. L., Kim, J. I. & Birge, R. B. alpha Vβ5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nature Cell Biol.2, 899–905 (2000). ArticleCAS Google Scholar
Wu, Y. C. & Horvitz, H. R. The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters. Cell93, 951–960 (1998). ArticleCAS Google Scholar
Liu, Q. A. & Hengartner, M. O. Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans. Cell93, 961–972 (1998). ArticleCAS Google Scholar
Wu, Y. C. & Horvitz, H. R. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature392, 501–504 (1998). ArticleADSCAS Google Scholar
Reddien, P. W. & Horvitz, H. R. CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans. Nature Cell Biol.2, 131–136 (2000). ArticleCAS Google Scholar
Shaham, S., Reddien, P. W., Davies, B. & Horvitz, H. R. Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3. Genetics153, 1655–1671 (1999). CAS Google Scholar
Freyd, G., Kim, S. K. & Horvitz, H. R. Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11. Nature344, 876–879 (1990). ArticleADSCAS Google Scholar
Conradt, B. & Horvitz, H. R. The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-I cell death activator gene. Cell98, 317–327 (1999). ArticleCAS Google Scholar
Hengartner, M. O. & Horvitz, H. R. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell76, 665–676 (1994). ArticleCAS Google Scholar
Hengartner, M. O. & Horvitz, H. R. Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2. Nature369, 318–320 (1994). ArticleADSCAS Google Scholar
Stanfield, G. M. & Horvitz, H. R. The ced-8 gene controls the timing of programmed cell deaths in C. elegans. Mol. Cell5, 423–433 (2000). ArticleCAS Google Scholar
Sulston, J. E., Albertson, D. G. & Thomson, J. N. The Caenorhabditis elegans male: postembryonic development of nongonadal structures. Dev. Biol.78, 542–576 (1980). ArticleCAS Google Scholar
Wu, Y. C., Stanfield, G. M. & Horvitz, H. R. NUC-1, a Caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis. Genes Dev.14, 536–548 (2000). CAS Google Scholar
Wyllie, A. H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature284, 555–556 (1980). ArticleADSCAS Google Scholar
Lang, R. A. & Bishop, J. M. Macrophages are required for cell death and tissue remodeling in the developing mouse eye. Cell74, 453–462 (1993). ArticleCAS Google Scholar
Little, G. H. & Flores, A. Inhibition of programmed cell death by catalase and phenylalanine methyl ester. Comp. Biochem. Physiol. Physiol.105, 79–83 (1993). ArticleCAS Google Scholar
Diez-Roux, G. & Lang, R. A. Macrophages induce apoptosis in normal cells in vivo. Development124, 3633–3638 (1997). CAS Google Scholar
Clark, S. G., Lu, X. & Horvitz, H. R. The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins. Genetics137, 987–997 (1994). CAS Google Scholar
Hobert, O. et al. Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene. Neuron19, 345–357 (1997). ArticleCAS Google Scholar