Another toll road (original) (raw)
- News & Views
- Published: 14 August 2003
Immunology
Nature volume 424, pages 736–737 (2003)Cite this article
- 1145 Accesses
- 26 Citations
- Metrics details
The immune response to microbes involves a well-known signalling cascade — but this doesn't control all aspects of anti-pathogen warfare. A second cascade, involving a new 'adaptor' protein, helps fill the gap.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Additional access options:
Figure 1: Fighting bacteria.

References
- Janeway, C. A. Jr & Medzhitov, R. Annu. Rev. Immunol. 20, 197–216 (2002).
Article CAS Google Scholar - Takeda, K. & Akira, S. Cell. Microbiol. 5, 143–153 (2003).
Article CAS Google Scholar - Hoebe, K. et al. Nature 424, 743–748 (2003).
Article CAS ADS Google Scholar - Yamamoto, M. et al. Science 301, 640–643 (2003).
Article CAS ADS Google Scholar - Alexopoulou, L., Holt, A. C., Medzhitov, R. & Flavell, R. A. Nature 413, 732–738 (2001).
Article CAS ADS Google Scholar - Poltorak, A. et al. Science 282, 2085–2088 (1998).
Article CAS ADS Google Scholar - Yamamoto, M. et al. J. Immunol. 169, 6668–6672 (2002).
Article CAS Google Scholar - Oshiumi, H. et al. Nature Immunol. 4, 161–167 (2003).
Article CAS Google Scholar - Yamamoto, M. et al. Nature 420, 324–329 (2002).
Article CAS ADS Google Scholar - Horng, T., Barton, G. M., Flavell, R. A. & Medzhitov, R. Nature 420, 329–333 (2002).
Article CAS ADS Google Scholar - O'Neill, L. A. J., Fitzgerald, K. A. & Bowie, A. G. Trends Immunol. 24, 286–289 (2003).
Article Google Scholar - Sharma, S. et al. Science 300, 1148–1151 (2003).
Article CAS ADS Google Scholar - Fitzgerald, K. A. et al. Nature Immunol. 4, 491–496 (2003).
Article CAS Google Scholar
Author information
Authors and Affiliations
- the Department of Medical Biophysics, Advanced Medical Discovery Institute, University Health Network, University of Toronto, 620 University Avenue, Toronto, M5G 2C1, Ontario, Canada
Wen-Chen Yeh & Nien-Jung Chen
Authors
- Wen-Chen Yeh
- Nien-Jung Chen
Rights and permissions
About this article
Cite this article
Yeh, WC., Chen, NJ. Another toll road.Nature 424, 736–737 (2003). https://doi.org/10.1038/424736a
- Issue date: 14 August 2003
- DOI: https://doi.org/10.1038/424736a