Verkerk, A.J. et al. Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell65, 905–914 (1991) ArticleCASPubMed Google Scholar
Turner, G., Webb, T., Wake, S. & Robinson, H. Prevalence of fragile X syndrome. Am. J. Med. Genet.64, 196–197 (1996) ArticleCASPubMed Google Scholar
Gedeon, A.K., Donnelly, A.J., Mulley, J.C., Kerr, B. & Turner, G. How many X-linked genes for non-specific mental retardation (MRX) are there? Am. J. Med. Genet.64, 158–162 (1996) ArticleCASPubMed Google Scholar
Gecz, J., Gedeon, A.K., Sutherland, G.R. & Mulley, J.C. Identification of the gene FMR2, associated with FRAXE mental retardation. Nature Genet.13, 105–108 (1996) ArticleCASPubMed Google Scholar
Bione, S. et al. Transcriptional organization of a 450-Kb region of the human X chromosome, in Xq28. Proc. Natl. Acad. Sci. USA90, 10977–10981 (1993) ArticleCASPubMed Google Scholar
Wu, S.K., Zeng, K., Wilson, I.A. & Balch, W.E. Structural insights into the function of Rab GDI superfamily. Trends Biochem. Sci.21, 472–476 (1996) ArticleCASPubMed Google Scholar
Pfeffer, S.R., Dirac-Svejstrup, A.B. & Soldati, T. Rab GDP dissociation inhibitor: putting rab GTPases in the right place. J. Biol. Chem.270, 17057–17059 (1995) ArticleCASPubMed Google Scholar
Sasaki, T. et al. Purification and characterization from bovine brain cytosol of a protein that inhibits the dissociation of GDP from and the subsequent binding of GTP to smg p25A, a ras p21-like GTP-binding protein. J. Biol. Chem.265, 2333–2337 (1990) CASPubMed Google Scholar
Fisher von Mollard, G., Stahl, B., Khokhlatchev, A., Suedhof, T.C. & Jahn, R. Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicle after stimulation of exocytosis. J. Biol. Chem.269, 10971–10974 (1994) Google Scholar
Fischer von Mollard, G., Stahl, B., Li, C., Suedhof, T.C. & Jahn, R. Rab proteins in regulated exocytosis. Trends Biochem. Sci.19, 164–168 (1994) ArticleCASPubMed Google Scholar
Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K. & Suedhof, T.C. Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Nature388, 593–598 (1997) ArticleCASPubMed Google Scholar
Takai, Y., Sasaki, T., Shirataki, H. & Nakanishi, H. Rab3A small GTP-binding protein in Ca(2+)-dependent exocytosis. Genes Cells1, 615–632 (1996) ArticleCASPubMed Google Scholar
Bean, A.J. & Scheller, R.H. Better late than never: a role for rabs late in exocytosis. Neuron19, 751–754 (1997) ArticleCASPubMed Google Scholar
Suedhof, T.C. Function of Rab3 GDP-GTP exchange. Neuron18, 519–522 (1997) Article Google Scholar
Sedlacek, Z., Koneki, B., Korn, B., Klauck, S.M. & Poustka, A. Evolutionary conservation and genomic organization of XA P-4, an Xq28 gene coding for a human rab GDP-dissociation inhibitor (GDI) . Mamm. Genome5, 633–639 (1994) ArticleCASPubMed Google Scholar
Chen, E.Y. et al. Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci . Hum. Mol. Genet.5, 659–668 (1996) ArticleCASPubMed Google Scholar
des Portes, V. et al. A gene for dominant nonspecific X-linked mental retardation is located in Xq28. Am. J. Hum. Genet.60, 903–909 (1997) CASPubMedPubMed Central Google Scholar
Hamel, B.C.J. et al. A gene for non specific X-linked mental retardation (MRX41) is located in the distal segment of Xq28. Am. J. Med. Genet.64, 131–133 (1996) ArticleCASPubMed Google Scholar
Ullrich, O. et al. Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. J. Biol. Chem.268, 18143 –18150 (1993) CASPubMed Google Scholar
Claes, S. et al. X-linked severe mental retardation and a progressive neurological disorder in a Belgian family: clinical and genetic studies. Clin. Genet.52, 155–161 ( 1997) ArticleCASPubMed Google Scholar
Schalk, I. et al. Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature381, 42–48 ( 1996) ArticleCASPubMed Google Scholar
Garrett, M.G., Zahner, J.E., Cheney, C.M. & Novick, P.J. Gdi1p encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway. EMBO J.13, 1718–1728 (1994) ArticleCASPubMedPubMed Central Google Scholar
Novick, P. & Zerial, M. The diversity of Rab proteins in vesicle transport. Curr. Opin. Cell Biol.9, 496 –504 (1997) ArticleCASPubMed Google Scholar
Bachner, D., Sedlacek, Z., Korn, B., Hameister, H. & Poustka, A. Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport. Hum. Mol. Genet.4, 701–708 (1995) ArticleCASPubMed Google Scholar
Banker, G.A. & Cowan, W.M. Rat hippocampal neurons in dispersed cell culture. Brain Res.126, 397–352 (1977) ArticleCASPubMed Google Scholar
Bartlett, W.P. & Banker, G.A. An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. II. Synaptic relationships. J. Neurosci.4, 1954–1965 (1984) ArticleCASPubMedPubMed Central Google Scholar
Geppert, M., Goda, Y., Stevens, C.F. & Suedhof, T.C. The small GTP-binding protein Rab3A regulates a late step in synaptic vescicles fusion. Nature387, 810–814 ( 1997) ArticleCASPubMed Google Scholar
Castillo, P.E. et al. Rab3A is essential for mossy fibre long-term potentiation in the hippocampus . Nature388, 590–593 (1997) ArticleCASPubMed Google Scholar
Cremers, F.P.M., van de Pol, T.J.R., van Kerkhoff, L.P.M., Wieringa, B. & Ropers, H.H. Cloning of a gene that is rearranged in patients with choroideremia. Nature357, 674–677 (1990). Article Google Scholar
Seabra M.C. Brown, M.S. & Goldstein, J.L. Retinal degeneration in choroideremia: deficiency of rab geranylgeranyl transferase . Science259, 377–381 (1993) ArticleCASPubMed Google Scholar
Bione, S. et al. Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy. Nature Genet.8, 323–327 (1994) ArticleCASPubMed Google Scholar
Spinardi, L., Mazars, R. & Theillet, C. Protocols for an improved detection of point mutations by SSCP. Nucleic Acids Res.19, 4009 ( 1991) ArticleCASPubMedPubMed Central Google Scholar
Gulisano, M., Broccoli, V., Pardini, C. & Boncinelli, E. Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex in the mouse. Eur. J. Neurosci.8, 1037–1050 (1996) ArticleCASPubMed Google Scholar
Burgaya, F., Menegon, A., Menegoz, M., Valtorta, F. & Girault, J.A. Focal adhesion kinase in rat central nervous system . Eur. J. Neurosci.7, 1810–1821 (1995) ArticleCASPubMed Google Scholar
Dascher, C. & Balch, W.E. Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus. J. Biol. Chem.269, 1437–1448 (1994) CASPubMed Google Scholar
Nuoffer, C., Peter, F. & Balch, W.E. Purification of His6-tagged Rab1 proteins using bacterial and insect cell expression systems. Methods Enzymol.257, 3–8 (1995) ArticleCASPubMed Google Scholar
Fisher von Mollard, G., Suedhof, T.C. & Jahn R. Nature349, 79–81 (1991). Article Google Scholar
Dekker, L.V., De Graan, P.N.E., Pijnappel, P., Oestreicher, A.B. & Gispen, W.H. Noradrenaline release from streptolysin O-permeated rat cortical synaptosomes: effects of calcium, phorbol esters, protein kinase inhibitors, and antibodies to the neuron-specific protein kinase C substrate B-50 (GAP-43). J. Neurochem.56, 1146–1153 (1991) ArticleCASPubMed Google Scholar
Billuart, P. et al. Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation. Nature392, 923–926 (1998) ArticleCASPubMed Google Scholar