Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation (original) (raw)

• Pieper, A.A., Verma, A., Zhang, J. & Snyder, S.H. Poly (ADP-ribose) polymerase, NO and cell death. Trends Pharmacol. Sci. 20, 171–181 (1999).
  Article CAS Google Scholar
• Cell Death: The Role of PARP (ed. Szabó, C.) (CRC Press, Boca Raton, Florida, 2000).
• Eliasson, M.J. et al. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nature Med. 3, 1089–1095 (1997).
  Article CAS Google Scholar
• Zingarelli, B., Salzman, A.L. & Szabó, C. Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. Circ. Res. 83, 85–94 (1998).
  Article CAS Google Scholar
• Burkart, V. et al. Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic β-cell destruction and diabetes development induced by streptozocin. Nature Med. 5, 314–319 (1999).
  Article CAS Google Scholar
• Pieper, A.A. et al. Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. Proc. Natl. Acad. Sci. USA 96, 3059–3064 (1997).
  Article Google Scholar
• Szabó, C., Cuzzocrea, S., Zingarelli, B., O'Connor, M. & Salzman, A.L. Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. J. Clin. Invest. 100, 723–735 (1997).
  Article Google Scholar
• Oliver, F.J. et al. Resistance to endotoxic shock as a consequence of defective NF-κB activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J. 18, 4446–4454 (1999).
  Article CAS Google Scholar
• Tooke, J.E. & Goh, K.L. Vascular function in Type 2 diabetes mellitus and pre-diabetes: the case for intrinsic endotheiopathy. Diabet. Med. 16, 710–715 (1999).
  Article CAS Google Scholar
• Keen, H., Clark, C. & Laakso, M. Reducing the burden of diabetes: managing cardiovascular disease. Diabetes Metab. Res. Rev. 15, 186–196 (1999).
  Article CAS Google Scholar
• Rodriguez-Manas, L. et al. Endothelial dysfunction and metabolic control in streptozotocin-induced diabetic rats. Br. J. Pharmacol. 123, 1495–1502 (1998).
  Article CAS Google Scholar
• Graier, W.F., Posch, K., Fleischhacker, E., Wascher, T.C. & Kostner, G.M. Increased superoxide anion formation in endothelial cells during hyperglycemia: an adaptive response or initial step of vascular dysfunction? Diabetes Res. Clin. Pract. 45, 153–160 (1999).
  Article CAS Google Scholar
• Nishikawa, T. et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404, 787–790 (2000).
  Article CAS Google Scholar
• Ischiropoulos, H. et al. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch. Biochem. Biophys. 298, 431–437 (1992).
  Article CAS Google Scholar
• Halliwell, B. What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo? FEBS Lett. 411, 157–160 (1997).
  Article CAS Google Scholar
• Furchgott, R.F. Studies on endothelium-dependent vasodilation and the endothelium-derived relaxing factor. Acta Physiol. Scand. 139, 257–270 (1990).
  Article CAS Google Scholar
• Pieper, G.M., Jordan, M., Adams, M.B. & Roza, A. Syngeneic pancreatic islet transplantation reverses endothelial dysfunction in experimental diabetes. Diabetes 44, 1106–1113 (1995).
  Article CAS Google Scholar
• Kobayashi, T. & Kamata, K. Effect of insulin treatment on smooth muscle contractility and endothelium-dependent relaxation in rat aortae from established STZ-induced diabetes. Br. J. Pharmacol. 127, 835–842 (1999).
  Article CAS Google Scholar
• Smith, S., Giriat, I., Schmitt, A. & de Lange, T. Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282, 1484–1487 (1998).
  Article CAS Google Scholar
• Sallmann, F.R., Vodenicharov, M.D., Wang, Z.Q. & Poirier, G.G. Characterization of sPARP-1. J. Biol. Chem. 275, 15504–15511 (2000).
  Article CAS Google Scholar
• Szabó, C., Zingarelli, B., O'Connor, M. & Salzman, A.L. DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc. Natl. Acad. Sci. USA 93, 1753–1758 (1996).
  Article Google Scholar
• Pieper, G.M., Langenstroer, P. & Siebeneich, W. Diabetic-induced endothelial dysfunction in rat aorta: role of hydroxyl radicals. Cardiovasc. Res. 34, 145–156 (1997).
  Article CAS Google Scholar
• Du, X., Stocklauser-Farber, K. & Rosen, P. Generation of reactive oxygen intermediates, activation of NF-κB, and induction of apoptosis in human endothelial cells by glucose: role of NO synthase? Free Radic. Biol. Med. 27, 752–763 (1999).
  Article CAS Google Scholar
• Karasu, C. Time course of changes in endothelium-dependent and -independent relaxation of chronically diabetic aorta: role of reactive oxygen species. Eur. J. Pharmacol. 392, 163–173 (2000).
  Article CAS Google Scholar
• Pieper, G.M., Moore-Hilton, G. & Roza, A.M. Evaluation of the mechanism of endothelial dysfunction in the genetically-diabetic BB rat. Life Sci. 58, PL147–512 (1996).
  Article CAS Google Scholar
• Cosentino, F., Hishikawa, K., Katusic, Z.S. & Luscher, T.F. High glucose increases NO synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation 96, 25–28 (1997).
  Article CAS Google Scholar
• Nishigaki, R. et al. Ultrastructural changes and immunohistochemical localization of nitric oxide synthase, advanced glycation end products and NF-κB in aorta of streptozotocin treated Mongolian gerbils. Nippon Ika Daigaku Zasshi 66, 166–175 (1999).
  Article CAS Google Scholar
• Eiserich, J.P. et al. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391, 393–397 (1998).
  Article CAS Google Scholar
• Szabó, C. et al. Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase. Proc. Natl. Acad. Sci. USA 95, 3867–3872 (1998).
  Article Google Scholar
• Pieper, G.M. & Riaz-ul-Haq, G. Activation of nuclear factor-κB in cultured endothelial cells by increased glucose concentration: prevention by calphostin C. J. Cardiovasc. Pharmacol. 30, 528–532 (1997).
  Article CAS Google Scholar
• Morigi, M. et al. Leukocyte-endothelial interaction is augmented by high glucose concentrations and hyperglycemia in a NF-κB-dependent fashion. J. Clin. Invest. 101, 1905–1915 (1998).
  Article CAS Google Scholar
• Barouch, F.C. et al. Integrin-mediated neutrophil adhesion and retinal leukostasis in diabetes. Invest. Ophthalmol. Vis. Sci 41, 1153–1158 (2000).
  CAS PubMed Google Scholar
• Wang, Z.Q. et al. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev. 9, 509–520 (1995).
  Article CAS Google Scholar
• Kaufmann, S.H., Mesner, P.W. Jr., Samejima, K., Tone, S. & Earnshaw, W.C. Detection of DNA cleavage in apoptotic cells. Methods Enzymol. 322, 3–15 (2000).
  Article CAS Google Scholar
• Shen, H. & Ong, C. Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility. Free Radic. Biol. Med. 28, 529–536 (2000).
  Article CAS Google Scholar
• Didier, M. et al. DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures. J. Neurosci. 16, 2238–2250 (1996).
  Article CAS Google Scholar
• Zhang, J. Use of biotinylated NAD to label and purify ADP-ribosylated proteins. Methods Enzymol. 280, 255–265 (1997).
  Article CAS Google Scholar
• Scott, G.S., Jakeman, L.B., Stokes, B.T. & Szabó, C. Peroxynitrite production and activation of poly (adenosine diphosphate-ribose) synthetase in spinal cord injury. Ann. Neurol. 45, 120–124 (1999).
  Article CAS Google Scholar
• Gerritsen, M.E. et al. Activation-dependent isolation and culture of murine pulmonary microvascular endothelium. Microcirculation 2, 151–163 (1995).
  Article CAS Google Scholar
• Klaidman L.K., Leung, A.C. & Adams, J.C. Jr. High-performance liquid chromatography analysis of oxidized and reduced pyridine dinucleotides in specific brain regions. Anal. Biochem. 228, 312–317 (1995).
  Article CAS Google Scholar
• Lamas S., Michel, T., Brenner, B.M, Marsden, P.A. Nitric oxide synthesis in endothelial cells: evidence for a pathway inducible by TNF-α. Am. J. Physiol. 261, C634–641 (1991).
  Article CAS Google Scholar
• Lantin-Hermoso, R.L. et al. Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium. Am. J. Physiol. 273, L119–126 (1997).
  CAS PubMed Google Scholar
• Gilad, E. et al. Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NF-κB activation. FASEB J. 12, 685–693 (1998).
  Article CAS Google Scholar
• Banasik, M., Komura, H., Shimoyama, M. & Ueda, K. Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase. J. Biol. Chem. 267, 1569–1575 (1992).
  CAS PubMed Google Scholar
• Virag, L. et al. Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity. Mol. Pharmacol. 56, 824–833 (1999).
  CAS PubMed Google Scholar