Kissing cousins: immunological and neurological synapses (original) (raw)

Nature Immunology volume 2, pages 575–576 (2001)Cite this article

Immunological synapse formation is essential for T cell activation. A recent paper in Science reports that immunological and neurological synapses utilize a common molecule, agrin.

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Figure 1: Comparison between the NMJ and neuronal versus immune synapses.

References

  1. Paul, W. E. & Seder, R. A. Cell 76, 241–251 (1994).
    Article CAS Google Scholar
  2. Dustin, M. et al. Cell 94, 667–677 (1998).
    Article CAS Google Scholar
  3. Khan, A. A., Bose, C., Yam, L. S., Soloski, M. J. & Rupp, F. Science 10, 565–594 (2001).
    Google Scholar
  4. Viola, A., Schroeder, S., Sakakibara, Y. & Lanzavecchia, A. Science 283, 680–682 (1999).
    Article CAS Google Scholar
  5. Sanes, J. R. & Lichtman, J. W. Annu. Rev. Neurosci. 22, 389–442 (1999).
    Article CAS Google Scholar
  6. Sheng, M. & Sala, C. Annu. Rev. Neurosci. 24, 1–29 (2001).
    Article CAS Google Scholar
  7. Dalva, M. B. et al. Cell 103, 945–956 (2000)
    Article CAS Google Scholar
  8. Bromley, S. K. et al. Annu. Rev. Immunol. 19, 375–396 (2001).
    Article CAS Google Scholar
  9. Valitutti, S. & Lanzavecchia, A. Immunol. Today 18, 299–304 (1997).
    Article CAS Google Scholar
  10. Huh, G. S. et al. Science 290, 2155–2159 (2000).
    Article CAS Google Scholar

Download references

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Authors and Affiliations

  1. Department of Pathology and Immunology, Washington University School of Medicine, 660 South Euclid, Saint Louis, 63110, MO, USA
    Andrey S. Shaw & Paul. M. Allen

Authors

  1. Andrey S. Shaw
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  2. Paul. M. Allen
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Shaw, A., Allen, P. Kissing cousins: immunological and neurological synapses.Nat Immunol 2, 575–576 (2001). https://doi.org/10.1038/89712

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