Bif-1/Endophilin B1: a candidate for crescent driving force in autophagy (original) (raw)

• Yoshimori T . Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 2004; 313: 453–458.
  Article CAS Google Scholar
• Levine B, Klionsky DJ . Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6: 463–477.
  Article CAS Google Scholar
• Karantza-Wadsworth V, Patel S, Kravchuk O, Chen G, Mathew R, Jin S et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev 2007; 21: 1621–1635.
  Article CAS Google Scholar
• Mathew R, Kongara S, Beaudoin B, Karp CM, Bray K, Degenhardt K et al. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev 2007; 21: 1367–1381.
  Article CAS Google Scholar
• Mizushima N, Levine B, Cuervo AM, Klionsky DJ . Autophagy fights disease through cellular self-digestion. Nature 2008; 451: 1069–1075.
  Article CAS Google Scholar
• Levine B, Kroemer G . Autophagy in the pathogenesis of disease. Cell 2008; 132: 27–42.
  Article CAS Google Scholar
• Kundu M, Thompson CB . Autophagy: basic principles and relevance to disease. Annu Rev Pathol 2008; 3: 427–455.
  Article CAS Google Scholar
• Shimizu S, Kanaseki T, Mizushima N, Mizuta T, Arakawa-Kobayashi S, Thompson CB et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004; 6: 1221–1228.
  Article CAS Google Scholar
• Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304: 1500–1502.
  Article CAS Google Scholar
• Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 2007; 9: 1142–1151.
  Article CAS Google Scholar
• Kroemer G, Levine B . Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol 2008; 9: 1004–1010.
  Article CAS Google Scholar
• Yoshimori T, Noda T . Toward unraveling membrane biogenesis in mammalian autophagy. Curr Opin Cell Biol 2008; 20: 401–407.
  Article CAS Google Scholar
• Eskelinen EL . New insights into the mechanisms of macroautophagy in mammalian cells. Int Rev Cell Mol Biol 2008; 266: 207–247.
  Article CAS Google Scholar
• Suzuki K, Ohsumi Y . Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae. FEBS Lett 2007; 581: 2156–2161.
  Article CAS Google Scholar
• Xie Z, Klionsky DJ . Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9: 1102–1109.
  Article CAS Google Scholar
• Mizushima N . Autophagy: process and function. Genes Dev 2007; 21: 2861–2873.
  Article CAS Google Scholar
• Kabeya Y, Kawamata T, Suzuki K, Ohsumi Y . Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae. Biochem Biophys Res Commun 2007; 356: 405–410.
  Article CAS Google Scholar
• Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P, Heim J . SH3GLB, a new endophilin-related protein family featuring an SH3 domain. Genomics 2001; 71: 222–234.
  Article CAS Google Scholar
• Cuddeback SM, Yamaguchi H, Komatsu K, Miyashita T, Yamada M, Wu C et al. Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem 2001; 276: 20559–20565.
  Article CAS Google Scholar
• Karbowski M, Jeong SY, Youle RJ . Endophilin B1 is required for the maintenance of mitochondrial morphology. J Cell Biol 2004; 166: 1027–1039.
  Article CAS Google Scholar
• Yang JS, Zhang L, Lee SY, Gad H, Luini A, Hsu VW . Key components of the fission machinery are interchangeable. Nat Cell Biol 2006; 8: 1376–1382.
  Article CAS Google Scholar
• Mizushima N, Yamamoto A, Hatano M, Kobayashi Y, Kabeya Y, Suzuki K et al. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol 2001; 152: 657–668.
  Article CAS Google Scholar
• Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19: 5720–5728.
  Article CAS Google Scholar
• Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4: 151–175.
  Article CAS Google Scholar
• Takahashi Y, Meyerkord CL, Wang HG . BARgaining membranes for autophagosome formation: Regulation of autophagy and tumorigenesis by Bif-1/Endophilin B1. Autophagy 2008; 4: 121–124.
  Article CAS Google Scholar
• Noda T, Kim J, Huang WP, Baba M, Tokunaga C, Ohsumi Y et al. Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol 2000; 148: 465–480.
  Article CAS Google Scholar
• Yamada T, Carson AR, Caniggia I, Umebayashi K, Yoshimori T, Nakabayashi K et al. Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast. J Biol Chem 2005; 280: 18283–18290.
  Article CAS Google Scholar
• Young AR, Chan EY, Hu XW, Kochl R, Crawshaw SG, High S et al. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 2006; 119 (Pt 18): 3888–3900.
  Article CAS Google Scholar
• Huttner WB, Schmidt A . Lipids, lipid modification and lipid-protein interaction in membrane budding and fission--insights from the roles of endophilin A1 and synaptophysin in synaptic vesicle endocytosis. Curr Opin Neurobiol 2000; 10: 543–551.
  Article CAS Google Scholar
• Farsad K, Ringstad N, Takei K, Floyd SR, Rose K, De Camilli P . Generation of high curvature membranes mediated by direct endophilin bilayer interactions. J Cell Biol 2001; 155: 193–200.
  Article CAS Google Scholar
• Modregger J, Schmidt AA, Ritter B, Huttner WB, Plomann M . Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. J Biol Chem 2003; 278: 4160–4167.
  Article CAS Google Scholar
• Masuda M, Takeda S, Sone M, Ohki T, Mori H, Kamioka Y et al. Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms. EMBO J 2006; 25: 2889–2897.
  Article CAS Google Scholar
• Gallop JL, Jao CC, Kent HM, Butler PJ, Evans PR, Langen R et al. Mechanism of endophilin N-BAR domain-mediated membrane curvature. EMBO J 2006; 25: 2898–2910.
  Article CAS Google Scholar
• Ringstad N, Nemoto Y, De Camilli P . The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. Proc Natl Acad Sci USA 1997; 94: 8569–8574.
  Article CAS Google Scholar
• Micheva KD, Ramjaun AR, Kay BK, McPherson PS . SH3 domain-dependent interactions of endophilin with amphiphysin. FEBS Lett 1997; 414: 308–312.
  Article CAS Google Scholar
• Weissenhorn W . Crystal structure of the endophilin-A1 BAR domain. J Mol Biol 2005; 351: 653–661.
  Article CAS Google Scholar
• Reggiori F, Shintani T, Nair U, Klionsky DJ . Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts. Autophagy 2005; 1: 101–109.
  Article CAS Google Scholar
• Webber JL, Young AR, Tooze SA . Atg9 trafficking in Mammalian cells. Autophagy 2007; 3: 54–56.
  Article CAS Google Scholar
• He C, Klionsky DJ . Atg9 trafficking in autophagy-related pathways. Autophagy 2007; 3: 271–274.
  Article CAS Google Scholar
• Mari M, Reggiori F . Atg9 trafficking in the yeast Saccharomyces cerevisiae. Autophagy 2007; 3: 145–148.
  Article CAS Google Scholar
• Kihara A, Kabeya Y, Ohsumi Y, Yoshimori T . Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep 2001; 2: 330–335.
  Article CAS Google Scholar
• Nakatogawa H, Ichimura Y, Ohsumi Y . Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. Cell 2007; 130: 165–178.
  Article CAS Google Scholar
• Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182: 685–701.
  Article CAS Google Scholar
• Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P . Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 2000; 275: 992–998.
  Article CAS Google Scholar
• Kihara A, Noda T, Ishihara N, Ohsumi Y . Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 2001; 152: 519–530.
  Article CAS Google Scholar
• Backer JM . The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem J 2008; 410: 1–17.
  Article CAS Google Scholar
• Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999; 402: 672–676.
  Article CAS Google Scholar
• Furuya N, Yu J, Byfield M, Pattingre S, Levine B . The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 2005; 1: 46–52.
  Article CAS Google Scholar
• Yan Y, Flinn RJ, Wu H, Schnur RS, Backer JM . hVps15 but not calcium/calmodulin is required for the activity and regulation of hVps34 in mammalian cells. Biochem J 2009; 417: 747–755.
  Article CAS Google Scholar
• Volinia S, Dhand R, Vanhaesebroeck B, MacDougall LK, Stein R, Zvelebil MJ et al. A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. EMBO J 1995; 14: 3339–3348.
  Article CAS Google Scholar
• Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 2006; 8: 688–699.
  Article CAS Google Scholar
• Itakura E, Kishi C, Inoue K, Mizushima N . Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG. Mol Biol Cell 2008; 19: 5360–5372.
  Article CAS Google Scholar
• Sun Q, Fan W, Chen K, Ding X, Chen S, Zhong Q . Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 2008; 105: 19211–19216.
  Article CAS Google Scholar
• Zeng X, Overmeyer JH, Maltese WA . Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. J Cell Sci 2006; 119 (Pt 2): 259–270.
  Article CAS Google Scholar
• Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, Nardacci R et al. Ambra1 regulates autophagy and development of the nervous system. Nature 2007; 447: 1121–1125.
  CAS Google Scholar
• Ropolo A, Grasso D, Pardo R, Sacchetti ML, Archange C, Lo Re A et al. The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells. J Biol Chem 2007; 282: 37124–37133.
  Article CAS Google Scholar
• Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA et al. Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nat Cell Biol 2008; 10: 776–787.
  Article CAS Google Scholar
• Obara K, Sekito T, Ohsumi Y . Assortment of phosphatidylinositol 3-kinase complexes – Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell 2006; 17: 1527–1539.
  Article CAS Google Scholar
• Liang C, Feng P, Ku B, Oh BH, Jung JU . UVRAG: a new player in autophagy and tumor cell growth. Autophagy 2007; 3: 69–71.
  Article CAS Google Scholar
• Mayer BJ . SH3 domains: complexity in moderation. J Cell Sci 2001; 114 (Pt 7): 1253–1263.
  CAS PubMed Google Scholar
• Hubner S, Couvillon AD, Kas JA, Bankaitis VA, Vegners R, Carpenter CL et al. Enhancement of phosphoinositide 3-kinase (PI 3-kinase) activity by membrane curvature and inositol-phospholipid-binding peptides. Eur J Biochem 1998; 258: 846–853.
  Article CAS Google Scholar
• Kuma A, Matsui M, Mizushima N . LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. Autophagy 2007; 3: 323–328.
  Article CAS Google Scholar
• Johnson EE, Overmeyer JH, Gunning WT, Maltese WA . Gene silencing reveals a specific function of hVps34 phosphatidylinositol 3-kinase in late versus early endosomes. J Cell Sci 2006; 119 (Pt 7): 1219–1232.
  Article CAS Google Scholar
• Peterson MR, Emr SD . The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic 2001; 2: 476–486.
  Article CAS Google Scholar
• Klionsky DJ, Emr SD . Autophagy as a regulated pathway of cellular degradation. Science 2000; 290: 1717–1721.
  Article CAS Google Scholar
• Wan J, Cheung AY, Fu WY, Wu C, Zhang M, Mobley WC et al. Endophilin B1 as a novel regulator of nerve growth factor/TrkA trafficking and neurite outgrowth. J Neurosci 2008; 28: 9002–9012.
  Article CAS Google Scholar
• Chipuk JE, Green DR . How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol 2008; 18: 157–164.
  Article CAS Google Scholar
• Reed JC . Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities. Cell Death Differ 2006; 13: 1378–1386.
  Article CAS Google Scholar
• Youle RJ, Strasser A . The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008; 9: 47–59.
  Article CAS Google Scholar
• Takahashi Y, Karbowski M, Yamaguchi H, Kazi A, Wu J, Sebti SM et al. Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. Mol Cell Biol 2005; 25: 9369–9382.
  Article CAS Google Scholar
• Yamaguchi H, Woods NT, Dorsey JF, Takahashi Y, Gjertsen NR, Yeatman T et al. SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis. J Biol Chem 2008; 283: 19112–19118.
  Article CAS Google Scholar
• Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122: 927–939.
  Article CAS Google Scholar
• Hsu YT, Youle RJ . Nonionic detergents induce dimerization among members of the Bcl-2 family. J Biol Chem 1997; 272: 13829–13834.
  Article CAS Google Scholar
• Karbowski M, Lee YJ, Gaume B, Jeong SY, Frank S, Nechushtan A et al. Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J Cell Biol 2002; 159: 931–938.
  Article CAS Google Scholar
• Suen DF, Norris KL, Youle RJ . Mitochondrial dynamics and apoptosis. Genes Dev 2008; 22: 1577–1590.
  Article CAS Google Scholar
• Kissova I, Plamondon LT, Brisson L, Priault M, Renouf V, Schaeffer J et al. Evaluation of the roles of apoptosis, autophagy, and mitophagy in the loss of plating efficiency induced by Bax expression in yeast. J Biol Chem 2006; 281: 36187–36197.
  Article CAS Google Scholar
• Gomes LC, Scorrano L . High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy. Biochim Biophys Acta 2008; 1777: 860–866.
  Article CAS Google Scholar
• Etxebarria A, Terrones O, Yamaguchi H, Landajuela A, Landeta O, Antonsson B et al. Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large-scale membrane morphological rearrangements. J Biol Chem 2009; 284: 4200–4212.
  Article CAS Google Scholar
• Peter BJ, Kent HM, Mills IG, Vallis Y, Butler PJ, Evans PR et al. BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science 2004; 303: 495–499.
  Article CAS Google Scholar
• Yue Z, Jin S, Yang C, Levine AJ, Heintz N . Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 2003; 100: 15077–15082.
  Article CAS Google Scholar
• Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T et al. The role of autophagy during the early neonatal starvation period. Nature 2004; 432: 1032–1036.
  Article CAS Google Scholar
• Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005; 169: 425–434.
  Article CAS Google Scholar