Functional profiling of the Saccharomyces cerevisiae genome (original) (raw)

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Acknowledgements

We thank I. Bastiaens, J. Howard Dees, R. Diaz, F. Dietrich, K. Freidel, N. Liebundguth, C. Rebischong, R. Schiavon, J. Schneider, T. Verhoeven and R. Wysoki for technical assistance. G.G. thanks C. Nislow for critical readings of the manuscript. This work was primarily supported by grants from the European Commission and the National Human Genome Research Institute (USA), the Medical Research Council of Canada, and the Swiss Office for Science.

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Authors and Affiliations

  1. Stanford Genome Technology Center, Stanford University, Palo Alto, California, 94304, USA
    Guri Giaever, Keith Anderson, Karen Davis, Zelek Herman, Daniel F. Jaramillo & Ronald W. Davis
  2. Department of Biochemistry, Stanford University School of Medicine, Stanford, California, 94305-5307, USA
    Angela M. Chu, Anna Astromoff, Adam Deutschbauer, Hong Liang, Daniel D. Shoemaker, Elizabeth A. Winzeler, Grace Yen & Ronald W. Davis
  3. Department of Molecular, Cellular & Developmental Biology, Yale University, New Haven, Connecticut, 06520-8103, USA
    Li Ni, Rhonda Bangham, Darlene LaBonte, Hong Liao, Lucy Liu, Chuanyun Luo, Petra Ross-Macdonald, Yonghong Yang & Michael Snyder
  4. Developmental Biology, Yale University,
    Li Ni, Rhonda Bangham, Darlene LaBonte, Hong Liao, Lucy Liu, Chuanyun Luo, Petra Ross-Macdonald, Yonghong Yang & Michael Snyder
  5. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, 06520-8103, USA
    Mark Gerstein & Ning Lan
  6. Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205-2185, USA
    Carla Connelly, Rong Mao, Siew Loon Ooi, Sharon Sookhai-Mahadeo, Elaine Youngman, Kexin Yu & Jef D. Boeke
  7. Genetics, Johns Hopkins University School of Medicine,
    Carla Connelly, Rong Mao, Siew Loon Ooi, Sharon Sookhai-Mahadeo, Elaine Youngman, Kexin Yu & Jef D. Boeke
  8. Department of Genetics, Washington University Medical School, St Louis, Missouri, 63110, USA
    Linda Riles, Matt Curtiss, Julie Wilhelmy & Mark Johnston
  9. Department of Biology, McGill University, Montreal, Québec, H3A 1B1, Canada
    Steeve Véronneau, Marc Lussier, Patrice Menard & Howard Bussey
  10. Rosetta Inpharmatics Inc., Washington, 98034, Kirkland, USA
    Sally Dow, Christopher J. Roberts, Greg Schimmack & Teresa R. Ward
  11. FYSA, Université catholique de Louvain, Place Croix du Sud, 2/20, 1348, Louvain-la-Neuve, Belgium
    Ankuta Lucau-Danila & Francoise Foury
  12. Université Libre de Bruxelles, Laboratoire de Physiologie Cellulaire, IBMM CP300, Gosselies, Belgium
    Bruno André
  13. Departments of Bioengineering and Chemistry, University of California, Berkeley
    Adam P. Arkin & Patrick Flaherty
  14. Physical Biosciences Division, Lawrence Berkeley National Laboratory, Howard Hughes Medical Institute, California, 94720-1770, Berkeley, USA
    Adam P. Arkin & Patrick Flaherty
  15. IRMW, Université Libre de Bruxelles, Brussels, B-1070, Belgium
    Mohamed El Bakkoury & Bart Scherens
  16. Departamento de Microbiologia y Genetica, Instituto de Microbiologia y Bioquimica, CSIC/Universidad de Salamanca, E-37007, Salamanca, Spain
    Rocio Benito & Jose L. Revuelta
  17. Department of Molecular Microbiology, Biozentrum, University of Basel, CH-4056, Basel, Switzerland
    Sophie Brachat & Peter Philippsen
  18. Department of Biology, University of Padova, I-35121, Padova, Italy
    Stefano Campanaro & Giorgio Valle
  19. EUROSCARF, Johann Wolfgang Goethe-Universität, Institute of Microbiology, Frankfurt/Main, D-60439, Germany
    Karl-Dieter Entian, Svenja Hempel, Peter Kötter & Matthias Rose
  20. Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, California, 94720-1770, USA
    Patrick Flaherty
  21. Gene Regulation and Chromosome Biology Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland, 21702, USA
    David J. Garfinkel, Deanna Gotte, Brenda Shafer, Jeffrey N. Strathern & Ching-yun Wang
  22. Institut fur Mikrobiologie, Heinrich-Heine-Universitat Dusseldorf, Dusseldorf, D-40225, Germany
    Ulrich Güldener & Johannes H. Hegemann
  23. Institute of Biological Sciences, University of Wales, UK, Aberystwyth, Wales, SY23 3DA
    Diane E. Kelly, Steven L. Kelly & David C. Lamb
  24. Department of Biology, Concordia University, Canada, Montreal, Québec, H3G 1M8
    Reginald K. Storms
  25. Katholieke Universiteit Leuven, Laboratory of Gene Technology, Leuven, B-3001, Belgium
    Marleen Voet & Guido Volckaert

Authors

  1. Guri Giaever
  2. Angela M. Chu
  3. Li Ni
  4. Carla Connelly
  5. Linda Riles
  6. Steeve Véronneau
  7. Sally Dow
  8. Ankuta Lucau-Danila
  9. Keith Anderson
  10. Bruno André
  11. Adam P. Arkin
  12. Anna Astromoff
  13. Mohamed El Bakkoury
  14. Rhonda Bangham
  15. Rocio Benito
  16. Sophie Brachat
  17. Stefano Campanaro
  18. Matt Curtiss
  19. Karen Davis
  20. Adam Deutschbauer
  21. Karl-Dieter Entian
  22. Patrick Flaherty
  23. Francoise Foury
  24. David J. Garfinkel
  25. Mark Gerstein
  26. Deanna Gotte
  27. Ulrich Güldener
  28. Johannes H. Hegemann
  29. Svenja Hempel
  30. Zelek Herman
  31. Daniel F. Jaramillo
  32. Diane E. Kelly
  33. Steven L. Kelly
  34. Peter Kötter
  35. Darlene LaBonte
  36. David C. Lamb
  37. Ning Lan
  38. Hong Liang
  39. Hong Liao
  40. Lucy Liu
  41. Chuanyun Luo
  42. Marc Lussier
  43. Rong Mao
  44. Patrice Menard
  45. Siew Loon Ooi
  46. Jose L. Revuelta
  47. Christopher J. Roberts
  48. Matthias Rose
  49. Petra Ross-Macdonald
  50. Bart Scherens
  51. Greg Schimmack
  52. Brenda Shafer
  53. Daniel D. Shoemaker
  54. Sharon Sookhai-Mahadeo
  55. Reginald K. Storms
  56. Jeffrey N. Strathern
  57. Giorgio Valle
  58. Marleen Voet
  59. Guido Volckaert
  60. Ching-yun Wang
  61. Teresa R. Ward
  62. Julie Wilhelmy
  63. Elizabeth A. Winzeler
  64. Yonghong Yang
  65. Grace Yen
  66. Elaine Youngman
  67. Kexin Yu
  68. Howard Bussey
  69. Jef D. Boeke
  70. Michael Snyder
  71. Peter Philippsen
  72. Ronald W. Davis
  73. Mark Johnston

Corresponding author

Correspondence toRonald W. Davis.

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Competing interests

The authors declare that they have no competing financial interests.

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Giaever, G., Chu, A., Ni, L. et al. Functional profiling of the Saccharomyces cerevisiae genome.Nature 418, 387–391 (2002). https://doi.org/10.1038/nature00935

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